Direkt zur Hauptnavigation springen Direkt zum Inhalt springen
info(at)avldigital.remove-this.de
Deutsch English
Filtern nach
Aktive Filter
Letzte Suchanfragen

Ergebnisse für *

Zeige Ergebnisse 1 bis 20 von 20.

  1. Can integrated care help in meeting the challenges posed on our health care systems by COVID-19? Some preliminary lessons learned from the european VIGOUR project
    Autor*in: Lindner S.; Kubitschke L.; Lionis C.; Anastasaki M.; Kirchmayer U.; Giacomini S.; De Luca V.; Iaccarino G.; Illario M.; Maddalena A.; Maritati A.; Conforti D.; Roba I.; Musian D.; Cano A.; Granell M.; Carriazo A. M.; Lama C. M.; Rodriguez S.; Guligowska A.; Kostka T.; Konijnendijk A.; Vitullo M.; Garcia-Rudolph A.; Sanchez J. S.; Maggio M.; Liotta G.; Tziraki C.; Roller-Wirnsberger R.
    Erschienen: 2020

    The COVID-19 pandemic puts health and care systems under pressure globally. This current paper highlights challenges arising in the care for older and vulnerable populations in this context and reflects upon possible perspectives for different... mehr

     

    The COVID-19 pandemic puts health and care systems under pressure globally. This current paper highlights challenges arising in the care for older and vulnerable populations in this context and reflects upon possible perspectives for different systems making use of nested integrated care approaches adapted during the work of the EU-funded project VIGOUR (“Evidence based Guidance to Scale-up Integrated Care in Europe”, funded by the European Union’s Health Programme 2014–2020 under Grant Agreement Number 826640).

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Schlagworte: Health care; Integrated care; Pandemic management; Social care; Vulnerable patients
    Lizenz:

    info:eu-repo/semantics/openAccess
  2. Next-generation care pathways for allergic rhinitis and asthma multimorbidity: A model for multimorbid non-communicable diseases—Meeting Report (Part 2)
    Autor*in: Bousquet J.; Pham-Thi N.; Bedbrook A.; Agache I.; Annesi-Maesano I.; Ansotegui I.; Anto J. M.; Bachert C.; Benveniste S.; Bewick M.; Billo N.; Bosnic-Anticevich S.; Bosse I.; Brusselle G.; Calderon M. A.; Canonica G. W.; Caraballo L.; Cardona V.; Carriazo A. M.; Cash E.; Cecchi L.; Chu D. K.; Colgan E.; Costa E.; Cruz A. A.; Czarlewski W.; Durham S.; Ebisawa M.; Erhola M.; Fauquert J. -L.; Fokkens W. J.; Fonseca J. A.; Guldemond N.; Iinuma T.; Illario M.; Klimek L.; Kuna P.; Kvedariene V.; Larenas-Linneman D.; Laune D.; Le L. T. T.; Lourenco O.; Malva J. O.; Marien G.; Menditto E.; Mullol J.; Munter L.; Okamoto Y.; Onorato G. L.; Papadopoulos N. G.; Perala M.; Pfaar O.; Phillips A.; Phillips J.; Pinnock H.; Portejoie F.; Quinones-Delgado P.; Rolland C.; Rodts U.; Samolinski B.; Sanchez-Borges M.; Schunemann H. J.; Shamji M.; Somekh D.; Togias A.; Toppila-Salmi S.; Tsiligianni I.; Usmani O.; Walker S.; Wallace D.; Valiulis A.; Van der Kleij R.; Ventura M. T.; Williams S.; Yorgancioglu A.; Zuberbier T.
    Erschienen: 2019

    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
  3. Rethinking palliative care in a public health context: addressing the needs of persons with non-communicable chronic diseases
    Autor*in: Tziraki C.; Grimes C.; Ventura F.; O'caoimh R.; Santana S.; Zavagli V.; Varani S.; Tramontano D.; Apostolo J.; Geurden B.; De Luca V.; Tramontano G.; Romano M. R.; Anastasaki M.; Lionis C.; Rodriguez-Acuna R.; Capelas M. L.; Dos Santos Afonso T.; Molloy D. W.; Liotta G.; Iaccarino G.; Triassi M.; Eklund P.; Roller-Wirnsberger R.; Illario M.
    Erschienen: 2020

    Non-communicable chronic diseases (NCCDs) are the main cause of morbidity and mortality globally. Demographic aging has resulted in older populations with more complex healthcare needs. This necessitates a multilevel rethinking of healthcare... mehr

     

    Non-communicable chronic diseases (NCCDs) are the main cause of morbidity and mortality globally. Demographic aging has resulted in older populations with more complex healthcare needs. This necessitates a multilevel rethinking of healthcare policies, health education and community support systems with digitalization of technologies playing a central role. The European Innovation Partnership on Active and Healthy Aging (A3) working group focuses on well-being for older adults, with an emphasis on quality of life and healthy aging. A subgroup of A3, including multidisciplinary stakeholders in health care across Europe, focuses on the palliative care (PC) model as a paradigm to be modified to meet the needs of older persons with NCCDs. This development paper delineates the key parameters we identified as critical in creating a public health model of PC directed to the needs of persons with NCCDs. This paradigm shift should affect horizontal components of public health models. Furthermore, our model includes vertical components often neglected, such as nutrition, resilience, well-being and leisure activities. The main enablers identified are information and communication technologies, education and training programs, communities of compassion, twinning activities, promoting research and increasing awareness amongst policymakers. We also identified key 'bottlenecks': inequity of access, insufficient research, inadequate development of advance care planning and a lack of co-creation of relevant technologies and shared decision-making. Rethinking PC within a public health context must focus on developing policies, training and technologies to enhance person-centered quality life for those with NCCD, while ensuring that they and those important to them experience death with dignity.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Schlagworte: integrated; multimorbidity; non-communicable chronic diseases (NCCDs); palliative care; public health
    Lizenz:

    info:eu-repo/semantics/openAccess
  4. Transitional palliative care interventions for older adults with advanced non-malignant diseases and frailty: a systematic review
    Autor*in: Sezgin D.; Hendry A.; Liew A.; O'Donovan M.; Salem M.; Carriazo A. M.; Lopez-Samaniego L.; Rodriguez-Acuna R.; Kennelly S.; Illario M.; Arnal Carda C.; Inzitari M.; Hammar T.; O'Caoimh R.
    Erschienen: 2020

    Purpose: To identify transitional palliative care (TPC) interventions for older adults with non-malignant chronic diseases and complex conditions. Design/methodology/approach: A systematic review of the literature was conducted. CINAHL, Cochrane... mehr

     

    Purpose: To identify transitional palliative care (TPC) interventions for older adults with non-malignant chronic diseases and complex conditions. Design/methodology/approach: A systematic review of the literature was conducted. CINAHL, Cochrane Library, Embase and Pubmed databases were searched for studies reporting TPC interventions for older adults, published between 2002 and 2019. The Crowe Critical Appraisal Tool was used for quality appraisal. Findings: A total of six studies were included. Outcomes related to TPC interventions were grouped into three categories: healthcare system-related outcomes (rehospitalisation, length of stay [LOS] and emergency department [ED] visits), patient-related outcomes and family/carer important outcomes. Overall, TPC interventions were associated with lower readmission rates and LOS, improved quality of life and better decision-making concerning hospice care among families. Outcomes for ED visits were unclear. Research limitations/implications: Positive outcomes related to healthcare services (including readmissions and LOS), patients (quality of life) and families (decision-making) were reported. However, the number of studies supporting the evidence were limited. Originality/value: Studies examining the effectiveness of existing care models to support transitions for those in need of palliative care are limited. This systematic literature review identified and appraised interventions aimed at improving transitions to palliative care in older adults with advanced non-malignant diseases or frailty.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Schlagworte: Advanced disease; Care model; Chronic disease; End-of-life care; Frailty; Non-malignant; Older adult; Palliative care; Transitional care
    Lizenz:

    info:eu-repo/semantics/openAccess
  5. European Summit on the Prevention and Self-Management of Chronic Respiratory Diseases: Report of the European Union Parliament Summit (29 March 2017)
    Autor*in: Hellings P. W.; Borrelli D.; Pietikainen S.; Agache I.; Akdis C.; Bachert C.; Bewick M.; Botjes E.; Constantinidis J.; Fokkens W.; Haahtela T.; Hopkins C.; Illario M.; Joos G.; Lund V.; Muraro A.; Pugin B.; Seys S.; Somekh D.; Stjarne P.; Valiulis A.; Valovirta E.; Bousquet J.
    Erschienen: 2017

    On March 29, 2017, a European Summit on the Prevention and Self-Management of Chronic Respiratory Diseases (CRD) was organized by the European Forum for Research and Education in Allergy and Airway Diseases. The event took place in the European... mehr

     

    On March 29, 2017, a European Summit on the Prevention and Self-Management of Chronic Respiratory Diseases (CRD) was organized by the European Forum for Research and Education in Allergy and Airway Diseases. The event took place in the European Parliament of Brussels and was hosted by MEP David Borrelli and MEP Sirpa Pietikainen. The aim of the Summit was to correspond to the needs of the European Commission and of patients suffering from CRD to join forces in Europe for the prevention and self-management. Delegates of the European Rhinologic Society, European Respiratory Society, European Academy of Allergy and Clinical Immunology, European Academy of Paediatrics, and European Patients Organization EFA all lectured on their vision and action plan to join forces in achieving adequate prevention and self-management of CRD in the context of Precision Medicine. Recent data highlight the preventive capacity of education on optimal care pathways for CRD. Self-management and patient empowerment can be achieved by novel educational on-line materials and by novel mobile health tools enabling patients and doctors to monitor and optimally treat CRDs based on the level of control. This report summarizes the contributions of the representatives of different European academic stakeholders in the field of CRD.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Schlagworte: Advocacy; Allergy; Asthma; EUFOREA; Mobile health technology
  6. Correlation between work impairment, scores of rhinitis severity and asthma using the MASK-air® App
    Autor*in: Bedard A.; Anto J. M.; Fonseca J. A.; Arnavielhe S.; Bachert C.; Bedbrook A.; Bindslev-Jensen C.; Bosnic-Anticevich S.; Cardona V.; Cruz A. A.; Fokkens W. J.; Garcia-Aymerich J.; Hellings P. W.; Ivancevich J. C.; Klimek L.; Kuna P.; Kvedariene V.; Larenas-Linnemann D.; Melen E.; Monti R.; Mosges R.; Mullol J.; Papadopoulos N. G.; Pham-Thi N.; Samolinski B.; Tomazic P. V.; Toppila-Salmi S.; Ventura M. T.; Yorgancioglu A.; Bousquet J.; Pfaar O.; Basagana X.; Aberer W.; Agache I.; Akdis C. A.; Akdis M.; Aliberti M. R.; Almeida R.; Amat F.; Angles R.; Annesi-Maesano I.; Ansotegui I. J.; Arnavielle S.; Asayag E.; Asarnoj A.; Arshad H.; Avolio F.; Bacci E.; Baiardini I.; Barbara C.; Barbagallo M.; Baroni I.; Barreto B. A.; Bateman E. D.; Bedolla-Barajas M.; Bewick M.; Beghe B.; Bel E. H.; Bergmann K. C.; Bennoor K. S.; Benson M.; Bertorello L.; Bialoszewski A. Z.; Bieber T.; Bialek S.; Bjermer L.; Blain H.; Blasi F.; Blua A.; Bochenska Marciniak M.; Bogus-Buczynska I.; Boner A. L.; Bonini M.; Bonini S.; Bosse I.; Bouchard J.; Boulet L. P.; Bourret R.; Bousquet P. J.; Braido F.; Briedis V.; Brightling C. E.; Brozek J.; Bucca C.; Buhl R.; Buonaiuto R.; Panaitescu C.; Burguete Cabanas M. T.; Burte E.; Bush A.; Caballero-Fonseca F.; Caillaud D.; Caimmi D.; Calderon M. A.; Camargos P. A. M.; Camuzat T.; Canfora G.; Canonica G. W.; Carlsen K. H.; Carreiro-Martins P.; Carriazo A. M.; Carr W.; Cartier C.; Casale T.; Castellano G.; Cecchi L.; Cepeda A. M.; Chavannes N. H.; Chen Y.; Chiron R.; Chivato T.; Chkhartishvili E.; Chuchalin A. G.; Chung K. F.; Ciaravolo M. M.; Ciceran A.; Cingi C.; Ciprandi G.; Carvalho Coehlo A. C.; Colas L.; Colgan E.; Coll J.; Conforti D.; Constantinidis J.; Correia de Sousa J.; Cortes-Grimaldo R. M.; Corti F.; Costa E.; Costa-Dominguez M. C.; Courbis A. L.; Cox L.; Crescenzo M.; Custovic A.; Czarlewski W.; Dahlen S. E.; D'Amato G.; Dario C.; da Silva J.; Dauvilliers Y.; Darsow U.; De Blay F.; De Carlo G.; Dedeu T.; de Fatima Emerson M.; De Feo G.; De Vries G.; De Martino B.; Motta Rubini N. P.; Deleanu D.; Denburg J. A.; Devillier P.; Di Capua Ercolano S.; Di Carluccio N.; Didier A.; Dokic D.; Dominguez-Silva M. G.; Douagui H.; Dray G.; Dubakiene R.; Durham S. R.; Du Toit G.; Dykewicz M. S.; El-Gamal Y.; Eklund P.; Eller E.; Emuzyte R.; Farrell J.; Farsi A.; Ferreira de Mello J.; Ferrero J.; Fink-Wagner A.; Fiocchi A.; Fontaine J. F.; Forti S.; Fuentes-Perez J. M.; Galvez-Romero J. L.; Gamkrelidze A.; Garcia-Cobas C. Y.; Garcia-Cruz M. H.; Gemicioglu B.; Genova S.; Christoff G.; Gereda J. E.; Gerth van Wijk R.; Gomez R. M.; Gomez-Vera J.; Gonzalez Diaz S.; Gotua M.; Grisle I.; Guidacci M.; Guldemond N. A.; Gutter Z.; Guzman M. A.; Haahtela T.; Hajjam J.; Hernandez L.; Hourihane J. O. '. B.; Huerta-Villalobos Y. R.; Humbert M.; Iaccarino G.; Illario M.; Ispayeva Z.; Jares E. J.; Jassem E.; Johnston S. L.; Joos G.; Jung K. S.; Just J.; Jutel M.; Kaidashev I.; Kalayci O.; Kalyoncu A. F.; Karjalainen J.; Kardas P.; Keil T.; Keith P. K.; Khaitov M.; Khaltaev N.; Kleine-Tebbe J.; Kowalski M. L.; Kuitunen M.; Kull I.; Kupczyk M.; Krzych-Falta E.; Lacwik P.; Laune D.; Lauri D.; Lavrut J.; Le L. T. T.; Lessa M.; Levato G.; Li J.; Lieberman P.; Lipiec A.; Lipworth B.; Lodrup Carlsen K. C.; Louis R.; Lourenco O.; Luna-Pech J. A.; Magnan A.; Mahboub B.; Maier D.; Mair A.; Majer I.; Malva J.; Mandajieva E.; Manning P.; De Manuel Keenoy E.; Marshall G. D.; Masjedi M. R.; Maspero J. F.; Mathieu-Dupas E.; Matta Campos J. J.; Matos A. L.; Maurer M.; Mavale-Manuel S.; Mayora O.; Meco C.; Medina-Avalos M. A.; Melo-Gomes E.; Meltzer E. O.; Menditto E.; Mercier J.; Miculinic N.; Mihaltan F.; Milenkovic B.; Moda G.; Mogica-Martinez M. D.; Mohammad Y.; Momas I.; Montefort S.; Mora Bogado D.; Morais-Almeida M.; Morato-Castro F. F.; Mota-Pinto A.; Moura Santo P.; Munter L.; Muraro A.; Murray R.; Naclerio R.; Nadif R.; Nalin M.; Napoli L.; Namazova-Baranova L.; Neffen H.; Niedeberger V.; Nekam K.; Neou A.; Nieto A.; Nogueira-Silva L.; Nogues M.; Novellino E.; Nyembue T. D.; O'Hehir R. E.; Odzhakova C.; Ohta K.; Okamoto Y.; Okubo K.; Onorato G. L.; Ortega Cisneros M.; Ouedraogo S.; Pali-Scholl I.; Palkonen S.; Panzner P.; Park H. S.; Papi A.; Passalacqua G.; Paulino E.; Pawankar R.; Pedersen S.; Pepin J. L.; Pereira A. M.; Persico M.; Phillips J.; Picard R.; Pigearias B.; Pin I.; Pitsios C.; Plavec D.; Pohl W.; Popov T. A.; Portejoie F.; Potter P.; Pozzi A. C.; Price D.; Prokopakis E. P.; Puy R.; Pugin B.; Pulido Ross R. E.; Przemecka M.; Rabe K. F.; Raciborski F.; Rajabian-Soderlund R.; Reitsma S.; Ribeirinho I.; Rimmer J.; Rivero-Yeverino D.; Rizzo J. A.; Rizzo M. C.; Robalo-Cordeiro C.; Rodenas F.; Rodo X.; Rodriguez Gonzalez M.; Rodriguez-Manas L.; Rolland C.; Rodrigues Valle S.; Roman Rodriguez M.; Romano A.; Rodriguez-Zagal E.; Rolla G.; Roller-Wirnsberger R. E.; Romano M.; Rosado-Pinto J.; Rosario N.; Rottem M.; Ryan D.; Sagara H.; Salimaki J.; Sanchez-Borges M.; Sastre-Dominguez J.; Scadding G. K.; Schunemann H. J.; Scichilone N.; Schmid-Grendelmeier P.; Sarquis Serpa F.; Shamai S.; Sheikh A.; Sierra M.; Simons F. E. R.; Siroux V.; Sisul J. C.; Skrindo I.; Sole D.; Somekh D.; Sondermann M.; Sooronbaev T.; Sova M.; Sorensen M.; Sorlini M.; Spranger O.; Stellato C.; Stelmach R.; Stukas R.; Sunyer J.; Strozek J.; Szylling A.; Tebyrica J. N.; Thibaudon M.; To T.; Todo-Bom A.; Trama U.; Triggiani M.; Suppli Ulrik C.; Urrutia-Pereira M.; Valenta R.; Valero A.; Valiulis A.; Valovirta E.; van Eerd M.; van Ganse E.; van Hage M.; Vandenplas O.; Vezzani G.; Vasankari T.; Vatrella A.; Verissimo M. T.; Viart F.; Viegi G.; Vicheva D.; Vontetsianos T.; Wagenmann M.; Walker S.; Wallace D.; Wang D. Y.; Waserman S.; Werfel T.; Westman M.; Wickman M.; Williams D. M.; Williams S.; Wilson N.; Wright J.; Wroczynski P.; Yakovliev P.; Yawn B. P.; Yiallouros P. K.; Yusuf O. M.; Zar H. J.; Zhang L.; Zhong N.; Zernotti M. E.; Zhanat I.; Zidarn M.; Zuberbier T.; Zubrinich C.; Zurkuhlen A.
    Erschienen: 2020

    Background: In allergic rhinitis, a relevant outcome providing information on the effectiveness of interventions is needed. In MASK-air (Mobile Airways Sentinel Network), a visual analogue scale (VAS) for work is used as a relevant outcome. This... mehr

     

    Background: In allergic rhinitis, a relevant outcome providing information on the effectiveness of interventions is needed. In MASK-air (Mobile Airways Sentinel Network), a visual analogue scale (VAS) for work is used as a relevant outcome. This study aimed to assess the performance of the work VAS work by comparing VAS work with other VAS measurements and symptom-medication scores obtained concurrently. Methods: All consecutive MASK-air users in 23 countries from 1 June 2016 to 31 October 2018 were included (14 189 users; 205 904 days). Geolocalized users self-assessed daily symptom control using the touchscreen functionality on their smart phone to click on VAS scores (ranging from 0 to 100) for overall symptoms (global), nose, eyes, asthma and work. Two symptom-medication scores were used: the modified EAACI CSMS score and the MASK control score for rhinitis. To assess data quality, the intra-individual response variability (IRV) index was calculated. Results: A strong correlation was observed between VAS work and other VAS. The highest levels for correlation with VAS work and variance explained in VAS work were found with VAS global, followed by VAS nose, eye and asthma. In comparison with VAS global, the mCSMS and MASK control score showed a lower correlation with VAS work. Results are unlikely to be explained by a low quality of data arising from repeated VAS measures. Conclusions: VAS work correlates with other outcomes (VAS global, nose, eye and asthma) but less well with a symptom-medication score. VAS work should be considered as a potentially useful AR outcome in intervention studies.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Schlagworte: asthma; MASK; rhiniti; score; visual analogue scale
    Lizenz:

    info:eu-repo/semantics/openAccess
  7. Next-generation care pathways for allergic rhinitis and asthma multimorbidity: A model for multimorbid non-communicable diseases—Meeting Report (Part 1)
    Autor*in: Bousquet J.; Pham-Thi N.; Bedbrook A.; Agache I.; Annesi-Maesano I.; Ansotegui I.; Anto J. M.; Bachert C.; Benveniste S.; Bewick M.; Billo N.; Bosnic-Anticevich S.; Bosse I.; Brusselle G.; Calderon M. A.; Canonica G. W.; Caraballo L.; Cardona V.; Carriazo A. M.; Cash E.; Cecchi L.; Chu D. K.; Colgan E.; Costa E.; Cruz A. A.; Czarlewski W.; Durham S.; Ebisawa M.; Erhola M.; Fauquert J. -L.; Fokkens W. J.; Fonseca J. A.; Guldemond N.; Iinuma T.; Illario M.; Klimek L.; Kuna P.; Kvedariene V.; Larenas-Linneman D.; Laune D.; Le L. T. T.; Lourenco O.; Malva J. O.; Marien G.; Menditto E.; Mullol J.; Munter L.; Okamoto Y.; Onorato G. L.; Papadopoulos N. G.; Perala M.; Pfaar O.; Phillips A.; Phillips J.; Pinnock H.; Portejoie F.; Quinones-Delgado P.; Rolland C.; Rodts U.; Samolinski B.; Sanchez-Borges M.; Schunemann H. J.; Shamji M.; Somekh D.; Togias A.; Toppila-Salmi S.; Tsiligianni I.; Usmani O.; Walker S.; Wallace D.; Valiulis A.; Van Der Kleij R.; Ventura M. T.; Williams S.; Yorgancioglu A.; Zuberbier T.
    Erschienen: 2019

    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
  8. ICT-supported interventions targeting pre-frailty: Healthcare recommendations from the personalised ICT supported service for independent living and active ageing (PERSSILAA) study
    Autor*in: O'Caoimh R.; Molloy D. W.; Fitzgerald C.; Van Velsen L.; Cabrita M.; Nassabi M. H.; de Vette F.; van Weering M. D.; Jansen-Kosterink S.; Kenter W.; Frazer S.; Rauter A. P.; Turkman A.; Antunes M.; Turkman F.; Silva M. S.; Martins A.; Costa H. S.; Albuquerque T. G.; Ferreira A.; Scherillo M.; De Luca V.; Abete P.; Colao A.; Garcia-Rudolph A.; Sanchez-Carrion R.; Sanchez J. S.; Gomez Aguilera E. J.; Illario M.; Hermens H.; Vollenbroek-Hutten M.
    Erschienen: 2018

    As society ages, healthcare systems are preparing for an increasing prevalence of frail, co-morbid and older community-dwellers at risk of adverse outcomes including falls, malnutrition, hospitalisation, institutionalisation and death. Early... mehr

     

    As society ages, healthcare systems are preparing for an increasing prevalence of frail, co-morbid and older community-dwellers at risk of adverse outcomes including falls, malnutrition, hospitalisation, institutionalisation and death. Early intervention is desirable and pre-frailty, before onset of functional decline, may represent a suitable transition stage to target, albeit evidence for reversibility and appropriate interventions are limited. No consensus on the definition, diagnosis or management of pre-frailty exists. This work describes 25 healthcare related findings from the recently completed PERsonalised ICT Supported Service for Independent Living and Active Ageing (PERSSILAA) project, funded under the 2013–2016 European Union Framework Programme 7 (grant #610359). PERSSILAA developed a comprehensive Information and Communication Technologies (ICT)-supported platform to screen, assess, intervene and then monitor community-dwellers in two regions (Enschede in the Netherlands and Campania in Italy) in order to address pre-frailty and promote active and healthy ageing, targeting three important pre-frailty subdomains: nutrition, cognition and physical function. Proposed definitions of pre-frailty, ICT-based approaches to screen and monitor for the onset of frailty and targeted management strategies employing technology across these domains are described. The potential of these 25 healthcare recommendations in the development of future European guidelines on the screening and prevention of frailty is explored.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einem Sammelband
    Format: Online
    Schlagworte: Frailty; Guideline; Healthcare recommendation; Information and communication technology; Pre-frailty
  9. Erratum to: Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5)(Clin Transl Allergy (2016) 6 (29) DOI:10.1186/s13601-016-0116-9)
    Autor*in: Bousquet J.; Farrell J.; Crooks G.; Hellings P.; Bel E. H.; Bewick M.; Chavannes N. H.; De Sousa J. C.; Cruz A. A.; Haahtela T.; Joos G.; Khaltaev N.; Malva J.; Muraro A.; Nogues M.; Palkonen S.; Pedersen S.; Robalo-Cordeiro C.; Samolinski B.; Strandberg T.; Valiulis A.; Yorgancioglu A.; Zuberbier T.; Bedbrook A.; Aberer W.; Adachi M.; Agusti A.; Akdis C. A.; Akdis M.; Ankri J.; Alonso A.; Annesi-Maesano I.; Ansotegui I. J.; Anto J. M.; Arnavielhe S.; Arshad H.; Bai C.; Baiardini I.; Bachert C.; Baigenzhin A. K.; Barbara C.; Bateman E. D.; Beghe B.; Kheder A. B.; Bennoor K. S.; Benson M.; Bergmann K. C.; Bieber T.; Bindslev-Jensen C.; Bjermer L.; Blain H.; Blasi F.; Boner A. L.; Bonini M.; Bonini S.; Bosnic-Anticevitch S.; Boulet L. P.; Bourret R.; Bousquet P. J.; Braido F.; Briggs A. H.; Brightling C. E.; Brozek J.; Buhl R.; Burney P. G.; Bush A.; Caballero-Fonseca F.; Caimmi D.; Calderon M. A.; Calverley P. M.; Camargos P. A. M.; Canonica G. W.; Camuzat T.; Carlsen K. H.; Carr W.; Carriazo A.; Casale T.; Cepeda Sarabia A. M.; Chatzi L.; Chen Y. Z.; Chiron R.; Chkhartishvili E.; Chuchalin A. G.; Chung K. F.; Ciprandi G.; Cirule I.; Cox L.; Costa D. J.; Custovic A.; Dahl R.; Dahlen S. E.; Darsow U.; De Carlo G.; De Blay F.; Dedeu T.; Deleanu D.; De Manuel Keenoy E.; Demoly P.; Denburg J. A.; Devillier P.; Didier A.; Dinh-Xuan A. T.; Djukanovic R.; Dokic D.; Douagui H.; Dray G.; Dubakiene R.; Durham S. R.; Dykewicz M. S.; El-Gamal Y.; Emuzyte R.; Fabbri L. M.; Fletcher M.; Fiocchi A.; Fink Wagner A.; Fonseca J.; Fokkens W. J.; Forastiere F.; Frith P.; Gaga M.; Gamkrelidze A.; Garces J.; Garcia-Aymerich J.; Gemicioglu B.; Gereda J. E.; Gonzalez Diaz S.; Gotua M.; Grisle I.; Grouse L.; Gutter Z.; Guzman M. A.; Heaney L. G.; Hellquist-Dahl B.; Henderson D.; Hendry A.; Heinrich J.; Heve D.; Horak F.; Hourihane J. O. B.; Howarth P.; Humbert M.; Hyland M. E.; Illario M.; Ivancevich J. C.; Jardim J. R.; Jares E. J.; Jeandel C.; Jenkins C.; Johnston S. L.; Jonquet O.; Julge K.; Jung K. S.; Just J.; Kaidashev I. P.; Khaitov M. R.; Kalayci O.; Kalyoncu A. F.; Keil T.; Keith P. K.; Klimek L.; Koffi N'Goran B.; Kolek V.; Koppelman G. H.; Kowalski M. L.; Kull I.; Kuna P.; Kvedariene V.; Lambrecht B.; Lau S.; Larenas-Linnemann D.; Laune D.; Le L. T. T.; Lieberman P.; Lipworth B.; Li J.; Lodrup Carlsen K.; Louis R.; MacNee W.; Magard Y.; Magnan A.; Mahboub B.; Mair A.; Majer I.; Makela M. J.; Manning P.; Mara S.; Marshall G. D.; Masjedi M. R.; Matignon P.; Maurer M.; Mavale-Manuel S.; Melen E.; Melo-Gomes E.; Meltzer E. O.; Menzies-Gow A.; Merk H.; Michel J. P.; Miculinic N.; Mihaltan F.; Milenkovic B.; Mohammad G. M. Y.; Molimard M.; Momas I.; Montilla-Santana A.; Morais-Almeida M.; Morgan M.; Mosges R.; Mullol J.; Nafti S.; Namazova-Baranova L.; Naclerio R.; Neou A.; Neffen H.; Nekam K.; Niggemann B.; Ninot G.; Nyembue T. D.; O'Hehir R. E.; Ohta K.; Okamoto Y.; Okubo K.; Ouedraogo S.; Paggiaro P.; Pali-Scholl I.; Panzner P.; Papadopoulos N.; Papi A.; Park H. S.; Passalacqua G.; Pavord I.; Pawankar R.; Pengelly R.; Pfaar O.; Picard R.; Pigearias B.; Pin I.; Plavec D.; Poethig D.; Pohl W.; Popov T. A.; Portejoie F.; Potter P.; Postma D.; Price D.; Rabe K. F.; Raciborski F.; Radier Pontal F.; Repka-Ramirez S.; Reitamo S.; Rennard S.; Rodenas F.; Roberts J.; Roca J.; Rodriguez Manas L.; Rolland C.; Roman Rodriguez M.; Romano A.; Rosado-Pinto J.; Rosario N.; Rosenwasser L.; Rottem M.; Ryan D.; Sanchez-Borges M.; Scadding G. K.; Schunemann H. J.; Serrano E.; Schmid-Grendelmeier P.; Schulz H.; Sheikh A.; Shields M.; Siafakas N.; Sibille Y.; Similowski T.; Simons F. E. R.; Sisul J. C.; Skrindo I.; Smit H. A.; Sole D.; Sooronbaev T.; Spranger O.; Stelmach R.; Sterk P. J.; Sunyer J.; Thijs C.; To T.; Todo-Bom A.; Triggiani M.; Valenta R.; Valero A. L.; Valia E.; Valovirta E.; Van Ganse E.; Van Hage M.; Vandenplas O.; Vasankari T.; Vellas B.; Vestbo J.; Vezzani G.; Vichyanond P.; Viegi G.; Vogelmeier C.; Vontetsianos T.; Wagenmann M.; Wallaert B.; Walker S.; Wang D. Y.; Wahn U.; Wickman M.; Williams D. M.; Williams S.; Wright J.; Yawn B. P.; Yiallouros P. K.; Yusuf O. M.; Zaidi A.; Zar H. J.; Zernotti M. E.; Zhang L.; Zhong N.; Zidarn M.; Mercier J.
    Erschienen: 2017

    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
  10. Frailty as the future core business of public health: Report of the activities of the A3 action group of the european innovation partnership on active and healthy ageing (EIP on AHA)
    Autor*in: Liotta G.; Ussai S.; Illario M.; O'caoimh R.; Cano A.; Holland C.; Roller-Winsberger R.; Capanna A.; Grecuccio C.; Ferraro M.; Paradiso F.; Ambrosone C.; Morucci L.; Scarcella P.; De Luca V.; Palombi L.
    Erschienen: 2018

    Background: The prevalence of frailty at population-level is expected to increase in Europe, changing the focus of Public Health. Here, we report on the activities of the A3 Action Group, focusing on managing frailty and supporting healthy ageing at... mehr

     

    Background: The prevalence of frailty at population-level is expected to increase in Europe, changing the focus of Public Health. Here, we report on the activities of the A3 Action Group, focusing on managing frailty and supporting healthy ageing at community level. Methods: A three-phased search strategy was used to select papers published between January 2016 and May 2018. In the third phase, the first manuscript draft was sent to all A3-Action Group members who were invited to suggest additional contributions to be included in the narrative review process. Results: A total of 56 papers were included in this report. The A3 Action Group developed three multidimensional tools predicting short–medium term adverse outcomes. Multiple factors were highlighted by the group as useful for healthcare planning: malnutrition, polypharmacy, impairment of physical function and social isolation were targeted to mitigate frailty and its consequences. Studies focused on the management of frailty highlighted that tailored interventions can improve physical performance and reduce adverse outcomes. Conclusions: This review shows the importance of taking a multifaceted approach when addressing frailty at community level. From a Public Health perspective, it is vital to identify factors that contribute to successful health and social care interventions and to the health systems sustainability.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Schlagworte: Community care; Frailty; Healthcare planning; Narrative review; Older adult; Public health
  11. Exploiting grk2 inhibition as a therapeutic option in experimental cancer treatment: Role of p53-induced mitochondrial apoptosis
    Autor*in: Gambardella J.; Fiordelisi A.; Santulli G.; Ciccarelli M.; Cerasuolo F. A.; Sala M.; Sommella E.; Campiglia P.; Illario M.; Iaccarino G.; Sorriento D.
    Erschienen: 2020

    The involvement of GRK2 in cancer cell proliferation and its counter-regulation of p53 have been suggested in breast cancer even if the underlying mechanism has not yet been elucidated. Furthermore, the possibility to pharmacologically inhibit GRK2... mehr

     

    The involvement of GRK2 in cancer cell proliferation and its counter-regulation of p53 have been suggested in breast cancer even if the underlying mechanism has not yet been elucidated. Furthermore, the possibility to pharmacologically inhibit GRK2 to delay cancer cell proliferation has never been explored. We investigated this possibility by setting up a study that combined in vitro and in vivo models to underpin the crosstalk between GRK2 and p53. To reach this aim, we took advantage of the different expression of p53 in cell lines of thyroid cancer (BHT 101 expressing p53 and FRO cells, which are p53-null) in which we overexpressed or silenced GRK2. The pharmacological inhibition of GRK2 was achieved using the specific inhibitor KRX-C7. The in vivo study was performed in Balb/c nude mice, where we treated BHT-101 or FRO-derived tumors with KRX-C7. In our in vitro model, FRO cells were unaffected by GRK2 expression levels, whereas BHT-101 cells were sensitive, thus suggesting a role for p53. The regulation of p53 by GRK2 is due to phosphorylative events in Thr-55, which induce the degradation of p53. In BHT-101 cells, the pharmacologic inhibition of GRK2 by KRX-C7 increased p53 levels and activated apoptosis through the mitochondrial release of cytochrome c. These KRX-C7-mediated events were also confirmed in cancer allograft models in nude mice. In conclusion, our data showed that GRK2 counter-regulates p53 expression in cancer cells through a kinase-dependent activity. Our results further corroborate the anti-proliferative role of GRK2 inhibitors in p53-sensitive tumors and propose GRK2 as a therapeutic target in selected cancers.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Schlagworte: Mitochondrial apoptosi; Thyroid cancer
    Lizenz:

    info:eu-repo/semantics/openAccess
  12. Mobile Technology in Allergic Rhinitis: Evolution in Management or Revolution in Health and Care?
    Autor*in: Bousquet J.; Ansotegui I. J.; Anto J. M.; Arnavielhe S.; Bachert C.; Basagana X.; Bedard A.; Bedbrook A.; Bonini M.; Bosnic-Anticevich S.; Braido F.; Cardona V.; Czarlewski W.; Cruz A. A.; Demoly P.; De Vries G.; Dramburg S.; Mathieu-Dupas E.; Erhola M.; Fokkens W. J.; Fonseca J. A.; Haahtela T.; Hellings P. W.; Illario M.; Ivancevich J. C.; Jormanainen V.; Klimek L.; Kuna P.; Kvedariene V.; Laune D.; Larenas-Linnemann D.; Lourenco O.; Onorato G. L.; Matricardi P. M.; Melen E.; Mullol J.; Papadopoulos N. G.; Pfaar O.; Pham-Thi N.; Sheikh A.; Tan R.; To T.; Tomazic P. V.; Toppila-Salmi S.; Tripodi S.; Wallace D.; Valiulis A.; van Eerd M.; Ventura M. T.; Yorgancioglu A.; Zuberbier T.
    Erschienen: 2019

    Smart devices and Internet-based applications (apps) are largely used in allergic rhinitis and may help to address some unmet needs. However, these new tools need to first of all be tested for privacy rules, acceptability, usability, and... mehr

     

    Smart devices and Internet-based applications (apps) are largely used in allergic rhinitis and may help to address some unmet needs. However, these new tools need to first of all be tested for privacy rules, acceptability, usability, and cost-effectiveness. Second, they should be evaluated in the frame of the digital transformation of health, their impact on health care delivery, and health outcomes. This review (1) summarizes some existing mobile health apps for allergic rhinitis and reviews those in which testing has been published, (2) discusses apps that include risk factors of allergic rhinitis, (3) examines the impact of mobile health apps in phenotype discovery, (4) provides real-world evidence for care pathways, and finally (5) discusses mobile health tools enabling the digital transformation of health and care, empowering citizens, and building a healthier society.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Schlagworte: App; Digital transformation of health; MASK; mHealth; Mobile technology; Rhiniti; Delivery of Health Care; Europe; Human; Mobile Application; Phenotype; Rhinitis; Allergic; Risk Factor; Telemedicine; Smartphone
  13. Monitoring biochemical and structural changes in human periodontal ligaments during orthodontic treatment by means of micro-raman spectroscopy
    Autor*in: Perillo L.; D'apuzzo F.; Illario M.; Laino L.; Spigna G. D.; Lepore M.; Camerlingo C.
    Erschienen: 2020

    The aim of the study was to examine the biochemical and structural changes occurring in the periodontal ligament (PDL) during orthodontic-force application using micro-Raman spectroscopy (µ-RS). Adolescent and young patients who needed orthodontic... mehr

     

    The aim of the study was to examine the biochemical and structural changes occurring in the periodontal ligament (PDL) during orthodontic-force application using micro-Raman spectroscopy (µ-RS). Adolescent and young patients who needed orthodontic treatment with first premolar extractions were recruited. Before extractions, orthodontic forces were applied using a closed-coil spring that was positioned between the molar and premolar. Patients were randomly divided into three groups, whose extractions were performed after 2, 7, and 14 days of force application. From the extracted premolars, PDL samples were obtained, and a fixation procedure with paraformaldehyde was adopted. Raman spectra were acquired for each PDL sample in the range of 1000–3200 cm−1 and the more relevant vibrational modes of proteins (Amide I and Amide III bands) and CH2 and CH3 modes were shown. Analysis indicated that the protein structure in the PDL samples after different time points of orthodontic-force application was modified. In addition, changes were observed in the CH2 and CH3 high wavenumber region due to local hypoxia and mechanical force transduction. The reported results indicated that µ-RS provides a valuable tool for investigating molecular interchain interactions and conformational modifications in periodontal fibers after orthodontic tooth movement, providing quantitative insight of time occurring for PDL molecular readjustment.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Schlagworte: CH; and CH; mode; Orthodontic tooth movement; Periodontal ligament; Protein; Raman spectroscopy; Adolescent; Adult; Female; Human; Male; Spectrum Analysis; Raman; Young Adult; Tooth Movement Techniques
    Lizenz:

    info:eu-repo/semantics/openAccess
  14. Operative definition of active and healthy ageing (AHA): Meeting report. Montpellier October 20-21, 2014
    Autor*in: Bousquet J.; Kuh D.; Bewick M.; Strandberg T.; Farrell J.; Pengelly R.; Joel M. E.; Rodriguez Manas L.; Mercier J.; Bringer J.; Camuzat T.; Bourret R.; Bedbrook A.; Kowalski M. L.; Samolinski B.; Bonini S.; Brayne C.; Michel J. P.; Venne J.; Viriot-Durandal P.; Alonso J.; Avignon A.; Bousquet P. J.; Combe B.; Cooper R.; Hardy R.; Iaccarino G.; Keil T.; Kesse-Guyot E.; Momas I.; Ritchie K.; Robine J. M.; Thijs C.; Tischer C.; Vellas B.; Zaidi A.; Alonso F.; Andersen Ranberg K.; Andreeva V.; Ankri J.; Arnavielhe S.; Arshad S. H.; Auge P.; Berr C.; Bertone P.; Blain H.; Blasimme A.; Buijs G. J.; Caimmi D.; Carriazo A.; Cesario A.; Coletta J.; Cosco T.; Criton M.; Cuisinier F.; Demoly P.; Fernandez-Nocelo S.; Fougere B.; Garcia-Aymerich J.; Goldberg M.; Guldemond N.; Gutter Z.; Harman D.; Hendry A.; Heve D.; Illario M.; Jeandel C.; Krauss-Etschmann S.; Krys O.; Kula D.; Laune D.; Lehmann S.; Maier D.; Malva J.; Matignon P.; Melen E.; Mercier G.; Moda G.; Nizinkska A.; Nogues M.; Ogneill M.; Pelissier J. Y.; Poethig D.; Porta D.; Postma D.; Puisieux F.; Richards M.; Robalo-Cordeiro C.; Romano V.; Roubille F.; Schulz H.; Scott A.; Senesse P.; Slagter S.; Smit H. A.; Somekh D.; Stafford M.; Suanzes J.; Todo-Bom A.; Touchon J.; Traver-Salcedo V.; Van Beurden M.; Varraso R.; Vergara I.; Villalba-Mora E.; Wilson N.; Wouters E.; Zins M.
    Erschienen: 2015

    The broad concept of Active and Healthy Ageing was proposed by WHO as the process of optimizing opportunities for health to enhance quality of life as people age. It applies to both individuals and population groups. A universal active and healthy... mehr

     

    The broad concept of Active and Healthy Ageing was proposed by WHO as the process of optimizing opportunities for health to enhance quality of life as people age. It applies to both individuals and population groups. A universal active and healthy ageing definition is not available and may differ depending on the purpose of the definition and/or the questions raised. The European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) has had a major impact but a definition of Active and Healthy Ageing is urgently needed. A meeting was organised in Montpellier October 20-21, 2014 as the annual conference of the EIP on AHA Reference Site MACVIA-LR (contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc Roussillon). The goal of the meeting was to propose an operational definition of Active and Healthy Ageing as well as tools that may be used for this definition. The current paper provides a summary of the plenary presentations that were given during the meeting.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Schlagworte: Active and Healthy Ageing; and Healthy Ageing; Definition; European Innovation Partnership on Active; MACVIA-LR
  15. Cabbage and fermented vegetables: From death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID-19
    Autor*in: Bousquet J.; Anto J. M.; Czarlewski W.; Haahtela T.; Fonseca S. C.; Iaccarino G.; Blain H.; Vidal A.; Sheikh A.; Akdis C. A.; Zuberbier T.; Hamzah Abdul Latiff A.; Abdullah B.; Aberer W.; Abusada N.; Adcock I.; Afani A.; Agache I.; Aggelidis X.; Agustin J.; Akdis M.; Al-Ahmad M.; Al-Zahab Bassam A.; Alburdan H.; Aldrey-Palacios O.; Alvarez Cuesta E.; Alwan Salman H.; Alzaabi A.; Amade S.; Ambrocio G.; Angles R.; Annesi-Maesano I.; Ansotegui I. J.; Anto J.; Ara Bardajo P.; Arasi S.; Arshad H.; Cristina Artesani M.; Asayag E.; Avolio F.; Azhari K.; Bachert C.; Bagnasco D.; Baiardini I.; Bajrovic N.; Bakakos P.; Bakeyala Mongono S.; Balotro-Torres C.; Barba S.; Barbara C.; Barbosa E.; Barreto B.; Bartra J.; Bateman E. D.; Battur L.; Bedbrook A.; Bedolla Barajas M.; Beghe B.; Bekere A.; Bel E.; Ben Kheder A.; Benson M.; Berghea E. C.; Bergmann K. -C.; Bernardini R.; Bernstein D.; Bewick M.; Bialek S.; Bialoszewski A.; Bieber T.; Billo N. E.; Bilo M. B.; Bindslev-Jensen C.; Bjermer L.; Bobolea I.; Bochenska Marciniak M.; Bond C.; Boner A.; Bonini M.; Bonini S.; Bosnic-Anticevich S.; Bosse I.; Botskariova S.; Bouchard J.; Boulet L. -P.; Bourret R.; Bousquet P.; Braido F.; Briggs A.; Brightling C. E.; Brozek J.; Brussino L.; Buhl R.; Bumbacea R.; Buquicchio R.; Burguete Cabanas M. -T.; Bush A.; Busse W. W.; Buters J.; Caballero-Fonseca F.; Calderon M. A.; Calvo M.; Camargos P.; Camuzat T.; Canevari F. R.; Cano A.; Canonica G. W.; Capriles-Hulett A.; Caraballo L.; Cardona V.; Carlsen K. -H.; Carmon Pirez J.; Caro J.; Carr W.; Carreiro-Martins P.; Carreon-Asuncion F.; Carriazo A. -M.; Casale T.; Castor M. -A.; Castro E.; Caviglia A. G.; Cecchi L.; Cepeda Sarabia A.; Chandrasekharan R.; Chang Y. -S.; Chato-Andeza V.; Chatzi L.; Chatzidaki C.; Chavannes N. H.; Chaves Loureiro C.; Chelninska M.; Chen Y.; Cheng L.; Chinthrajah S.; Chivato T.; Chkhartishvili E.; Christoff G.; Chrystyn H.; Chu D. K.; Chua A.; Chuchalin A.; Chung K. F.; Ciceran A.; Cingi C.; Ciprandi G.; Cirule I.; Coelho A. C.; Compalati E.; Constantinidis J.; Correia de Sousa J.; Costa E. M.; Costa D.; Costa Dominguez M. D. C.; Coste A.; Cottini M.; Cox L.; Crisci C.; Crivellaro M. A.; Cruz A. A.; Cullen J.; Custovic A.; Cvetkovski B.; D'Amato G.; da Silva J.; Dahl R.; Dahlen S. -E.; Daniilidis V.; DarjaziniNahhas L.; Darsow U.; Davies J.; de Blay F.; De Feo G.; De Guia E.; de los Santos C.; De Manuel Keenoy E.; De Vries G.; Deleanu D.; Demoly P.; Denburg J.; Devillier P.; Didier A.; Dimic Janjic S.; Dimou M.; Dinh-Xuan A. T.; Djukanovic R.; Do Ceu Texeira M.; Dokic D.; Dominguez Silva M. G.; Douagui H.; Douladiris N.; Doulaptsi M.; Dray G.; Dubakiene R.; Dupas E.; Durham S.; Duse M.; Dykewicz M.; Ebo D.; Edelbaher N.; Eiwegger T.; Eklund P.; El-Gamal Y.; El-Sayed Z. A.; El-Sayed S. S.; El-Seify M.; Emuzyte R.; Enecilla L.; Erhola M.; Espinoza H.; Espinoza Contreras J. G.; Farrell J.; Fernandez L.; Fink Wagner A.; Fiocchi A.; Fokkens W. J.; Lenia F.; Fonseca J. A.; Fontaine J. -F.; Forastiere F.; Fuentes Perez J. M.; Gaerlan-Resureccion E.; Gaga M.; Galvez Romero J. L.; Gamkrelidze A.; Garcia A.; Garcia Cobas C. Y.; Garcia Cruz M. D. L. L. H.; Gayraud J.; Gelardi M.; Gemicioglu B.; Gennimata D.; Genova S.; Gereda J.; Gerth van Wijk R.; Giuliano A.; Gomez M.; Gonzalez Diaz S.; Gotua M.; Grigoreas C.; Grisle I.; Gualteiro L.; Guidacci M.; Guldemond N.; Gutter Z.; Guzman A.; Halloum R.; Halpin D.; Hamelmann E.; Hammadi S.; Harvey R.; Heffler E.; Heinrich J.; Hejjaoui A.; Hellquist-Dahl B.; Hernandez Velazquez L.; Hew M.; Hossny E.; Howarth P.; Hrubisko M.; Huerta Villalobos Y. R.; Humbert M.; Salina H.; Hyland M.; Ibrahim M.; Ilina N.; Illario M.; Incorvaia C.; Infantino A.; Irani C.; Ispayeva Z.; Ivancevich J. -C.; E. J. Jares E.; Jarvis D.; Jassem E.; Jenko K.; Jimeneracruz Uscanga R. D.; Johnston S. L.; Joos G.; Jost M.; Julge K.; Jung K. -S.; Just J.; Jutel M.; Kaidashev I.; Kalayci O.; Kalyoncu F.; Kapsali J.; Kardas P.; Karjalainen J.; Kasala C. A.; Katotomichelakis M.; Kavaliukaite L.; Kazi B. S.; Keil T.; Keith P.; Khaitov M.; Khaltaev N.; Kim Y. -Y.; Kirenga B.; Kleine-Tebbe J.; Klimek L.; Koffi N'Goran B.; Kompoti E.; Kopac P.; Koppelman G.; KorenJeverica A.; Koskinen S.; Kosnik M.; Kostov K. V.; Kowalski M. L.; Kralimarkova T.; Kramer Vrscaj K.; Kraxner H.; Kreft S.; Kritikos V.; Kudlay D.; Kuitunen M.; Kull I.; Kuna P.; Kupczyk M.; Kvedariene V.; Kyriakakou M.; Lalek N.; Landi M.; Lane S.; Larenas-Linnemann D.; Lau S.; Laune D.; Lavrut J.; Le L.; Lenzenhuber M.; Lessa M.; Levin M.; Li J.; Lieberman P.; Liotta G.; Lipworth B.; Liu X.; Lobo R.; Lodrup Carlsen K. C.; Lombardi C.; Louis R.; Loukidis S.; Lourenco O.; Luna Pech J. A.; Madjar B.; Maggi E.; Magnan A.; Mahboub B.; Mair A.; Mais Y.; Maitland van der Zee A. -H.; Makela M.; Makris M.; Malling H. -J.; Mandajieva M.; Manning P.; Manousakis M.; Maragoudakis P.; Marseglia G.; Marshall G.; Reza Masjedi M.; Maspero J. F.; Matta Campos J. J.; Maurer M.; Mavale-Manuel S.; Meco C.; Melen E.; Melioli G.; Melo-Gomes E.; Meltzer E. O.; Menditto E.; Menzies-Gow A.; Merk H.; Michel J. -P.; Micheli Y.; Miculinic N.; Midao L.; Mihaltan F.; Mikos N.; Milanese M.; Milenkovic B.; Mitsias D.; Moalla B.; Moda G.; Mogica Martinez M. D.; Mohammad Y.; Moin M.; Molimard M.; Momas I.; Mommers M.; Monaco A.; Montefort S.; Mora D.; Morais-Almeida M.; Mosges R.; Mostafa B.; Mullol J.; Munter L.; Muraro A.; Murray R.; Musarra A.; Mustakov T.; Naclerio R.; Nadeau K. C.; Nadif R.; Nakonechna A.; Namazova-Baranova L.; Navarro-Locsin G.; Neffen H.; Nekam K.; Neou A.; Nettis E.; Neuberger D.; Nicod L.; Nicola S.; Niederberger-Leppin V.; Niedoszytko M.; Nieto A.; Novellino E.; Nunes E.; Nyembue D.; O'Hehir R.; Odjakova C.; Ohta K.; Okamoto Y.; Okubo K.; Oliver B.; Onorato G. L.; Pia Orru M.; Ouedraogo S.; Ouoba K.; Paggiaro P. L.; Pagkalos A.; Pajno G.; Pala G.; Palaniappan S. P.; Pali-Scholl I.; Palkonen S.; Palmer S.; Panaitescu Bunu C.; Panzner P.; Papadopoulos N. G.; Papanikolaou V.; Papi A.; Paralchev B.; Paraskevopoulos G.; Park H. -S.; Passalacqua G.; Patella V.; Pavord I.; Pawankar R.; Pedersen S.; Peleve S.; Pellegino S.; Pereira A.; Perez T.; Perna A.; Peroni D.; Pfaar O.; Pham-Thi N.; Pigearias B.; Pin I.; Piskou K.; Pitsios C.; Plavec D.; Poethig D.; Pohl W.; Poplas Susic A.; Popov T. A.; Portejoie F.; Potter P.; Poulsen L.; Prados-Torres A.; Prarros F.; Price D.; Prokopakis E.; Puggioni F.; Puig-Domenech E.; Puy R.; Rabe K.; Raciborski F.; Ramos J.; Recto M. T.; Reda S. M.; Regateiro F. S.; Reider N.; Reitsma S.; Repka-Ramirez S.; Ridolo E.; Rimmer J.; Rivero Yeverino D.; Angelo Rizzo J.; Robalo-Cordeiro C.; Roberts G.; Roche N.; Rodriguez Gonzalez M.; Rodriguez Zagal E.; Rolla G.; Rolland C.
    Erschienen: 2021

    Large differences in COVID-19 death rates exist between countries and between regions of the same country. Some very low death rate countries such as Eastern Asia, Central Europe, or the Balkans have a common feature of eating large quantities of... mehr

     

    Large differences in COVID-19 death rates exist between countries and between regions of the same country. Some very low death rate countries such as Eastern Asia, Central Europe, or the Balkans have a common feature of eating large quantities of fermented foods. Although biases exist when examining ecological studies, fermented vegetables or cabbage have been associated with low death rates in European countries. SARS-CoV-2 binds to its receptor, the angiotensin-converting enzyme 2 (ACE2). As a result of SARS-CoV-2 binding, ACE2 downregulation enhances the angiotensin II receptor type 1 (AT1R) axis associated with oxidative stress. This leads to insulin resistance as well as lung and endothelial damage, two severe outcomes of COVID-19. The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is the most potent antioxidant in humans and can block in particular the AT1R axis. Cabbage contains precursors of sulforaphane, the most active natural activator of Nrf2. Fermented vegetables contain many lactobacilli, which are also potent Nrf2 activators. Three examples are: kimchi in Korea, westernized foods, and the slum paradox. It is proposed that fermented cabbage is a proof-of-concept of dietary manipulations that may enhance Nrf2-associated antioxidant effects, helpful in mitigating COVID-19 severity.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Schlagworte: cabbage; diet; fermented vegetable; kimchi; Lactobacillu; sulforaphane
    Lizenz:

    info:eu-repo/semantics/openAccess
  16. Positioning the principles of precision medicine in care pathways for allergic rhinitis and chronic rhinosinusitis – A EUFOREA-ARIA-EPOS-AIRWAYS ICP statement
    Autor*in: Hellings P. W.; Fokkens W. J.; Bachert C.; Akdis C. A.; Bieber T.; Agache I.; Bernal-Sprekelsen M.; Canonica G. W.; Gevaert P.; Joos G.; Lund V.; Muraro A.; Onerci M.; Zuberbier T.; Pugin B.; Seys S. F.; Bousquet J.; Aberer W.; Akdis M.; Alobid I.; Ankri J.; Annesi-Maesano I.; Ansotegui I. J.; Anto J. M.; Arnavielhe S.; Arshad H.; Asarnoj A.; Avolio F.; Baiardini I.; Barbagallo M.; Barbara C.; Baroody F.; Bateman E. D.; Bedbrook A.; Beghe B.; Bel E. H.; Bennoor K. S.; Benson M.; Bergmann K. C.; Bewick M.; Bialoszewski A. Z.; Bindslev-Jensen C.; Bjermer L.; Blain H.; Blasi F.; Boner A. L.; Bonini M.; Bonini S.; Bosnic-Anticevich S.; Bosse I.; Bouchard J.; Boulet L. P.; Bourret R.; Bousquet P. J.; Braido F.; Briggs A. H.; Brightling C. E.; Brozek J.; Bucca C.; Buhl R.; Bunu C.; Burte E.; Bush A.; Caballero-Fonseca F.; Caimmi D. P.; Calderon M. A.; Camargos P. A.; Camuzat T.; Cardona V.; Carlsen K. H.; Carr W.; Carreiro-Martins P.; Carriazo A. M.; Casale T.; Cepeda Sarabia A. M.; Cervin A.; Cesari M.; Chatzi L.; Chavannes N. H.; Chiron R.; Chivato T.; Chkhartishvili E.; Chuchalin A. G.; Chung K. F.; Ciprandi G.; Cohen N.; Conzalez Diaz S.; Cox L.; Crooks G.; Cruz A. A.; Custovic A.; Dahl R.; Dahlen S. E.; Darsow U.; De Carlo G.; De Manuel Keenoy E.; de Sousa J. C.; De Vries G.; Dedeu T.; Deleanu D.; Demoly P.; Denburg J. A.; Devillier P.; Didier A.; Dinh-Xuan A. T.; Dokic D.; Douagui H.; Douglas R.; Dray G.; Du Toit G.; Dubakiene R.; Durham S. R.; Dykewicz M. S.; Eklund P.; El-Gamal Y.; Ellers E.; Emuzyte R.; Farrell J.; Fink Wagner A.; Fiocchi A.; Fletcher M.; Fonseca J.; Forastiere F.; Gaga M.; Gamkrelidze A.; Gemicioglu B.; Georgalas C.; Gereda J. E.; Goossens H.; Grisle I.; Guldemond N. A.; Gutter Z.; Guzman M. A.; Haahtela T.; Harvey R.; Heinrich J.; Hellquist-Dahl B.; Hopkins C.; Horak F.; Hourihane J. O.; Humbert M.; Hyland M.; Iaccarino G.; Illario M.; Jares E. J.; Jeandel C.; Johnston S. L.; Jonquet O.; Jung K. S.; Just J.; Jutel M.; Kaidashev I. P.; Kalayci O.; Kalogjera L.; Kalyoncu A. F.; Kardas P.; Keil T.; Keith P. K.; Kerkhof M.; Kern B.; Kerstjens H. A.; Khaitov M.; Khaltaev N.; Klimek L.; Kogevinas M.; Kolek V.; Koppelman G. H.; Kowalski M.; Kowalski M. L.; Kuitunen M.; Kull I.; Kuna P.; Kvedariene V.; Lambrecht B.; Larenas-Linnemann D.; Lau S.; Laune D.; Le L. T.; Li J.; Lieberman P.; Lipworth B.; Lodrup Carlsen K. C.; Louis R.; Lund V. J.; Lupinek C.; MacNee W.; Magar Y.; Magnan A.; Mahboub B.; Maier D.; Majer I.; Malva J.; Manning P.; Marshall G. D.; Masjedi M. R.; Mathieu-Dupas E.; Maurer M.; Mavale-Manuel S.; Melen E.; Melo-Gomes E.; Meltzer E. O.; Mercier J.; Merk H.; Miculinic N.; Mihaltan F.; Milenkovic B.; Millot-Keurinck J.; Mohammad Y.; Momas I.; Morais-Almeida M.; Mosges R.; Mullol J.; Murray R.; Naclerio R.; Nadif R.; Namazova-Baranova L.; Neffen H.; Nekam K.; Nieto A.; Nogues M.; Nyembue T. D.; O'Hehir R. E.; Ohta K.; Okamoto Y.; Okubo K.; Olive-Elias M.; Ouedraogo S.; Paggiaro P.; Pali-Scholl I.; Palkonen S.; Panzner P.; Papadopoulos N. G.; Papi A.; Park H. S.; Passalacqua G.; Niggemann B.; Nogueira-Silva L.; Pereira A. M.; Pfaar O.; Picard R.; Pigearias B.; Pin I.; Plavec D.; Pohl W.; Popov T. A.; Portejoie F.; Postma D.; Potter P.; Poulsen L. K.; Price D.; Rabe K. F.; Raciborski F.; Riechelmann H.; Robalo-Cordeiro C.; Roberts G.; Rodenas F.; Rodriguez-Manas L.; Rolland C.; Roman Rodriguez M.; Romano A.; Rosado-Pinto J.; Rosario N.; Rottem M.; Ryan D.; Samolinski B.; Sanchez-Borges M.; Sastre-Dominguez J.; Scadding G. K.; Schlosser R.; Schmid-Grendelmeier P.; Schunemann H. J.; Scichilone N.; Senior B.; Serrano E.; Sheikh A.; Shields M.; Simons F. E. R.; Siroux V.; Sisul J. C.; Skrindo I.; Smit H. A.; Sole D.; Sooronbaev T.; Spranger O.; Stellato C.; Stelmach R.; Sterk P. J.; Strandberg T.; Sunyer J.; Thijs C.; Thomas M.; Todo-Bom A.; Tomazic P. V.; Toskala E.; Triggiani M.; Valenta R.; Valero A.; Valiulis A.; Valovirta E.; van Eerd M.; van Ganse E.; van Hage M.; van Wick R. G.; Vandenplas O.; Varona L. L.; Vazankari T.; Vellas B.; Ventura M. T.; Vezzani G.; Viegi G.; Voegels R.; Vontetsianos T.; Wagenmann M.; Wahn U.; Walker S.; Wang D. Y.; Wang Y.; Werfel T.; Whalley B.; Wickman M.; Williams D. M.; Williams S.; Wilson N.; Wormald P. J.; Wright J.; Yawn B. P.; Yiallouros P. K.; Yorgancioglu A.; Young I.; Yusuf O. M.; Zaidi A.; Zar H. J.; Zernotti M. E.; Zhang L.; Zhong N.; Zidarn M.
    Erschienen: 2017

    Precision medicine (PM) is increasingly recognized as the way forward for optimizing patient care. Introduced in the field of oncology, it is now considered of major interest in other medical domains like allergy and chronic airway diseases, which... mehr

     

    Precision medicine (PM) is increasingly recognized as the way forward for optimizing patient care. Introduced in the field of oncology, it is now considered of major interest in other medical domains like allergy and chronic airway diseases, which face an urgent need to improve the level of disease control, enhance patient satisfaction and increase effectiveness of preventive interventions. The combination of personalized care, prediction of treatment success, prevention of disease and patient participation in the elaboration of the treatment plan is expected to substantially improve the therapeutic approach for individuals suffering from chronic disabling conditions. Given the emerging data on the impact of patient stratification on treatment outcomes, European and American regulatory bodies support the principles of PM and its potential advantage over current treatment strategies. The aim of the current document was to propose a consensus on the position and gradual implementation of the principles of PM within existing adult treatment algorithms for allergic rhinitis (AR) and chronic rhinosinusitis (CRS). At the time of diagnosis, prediction of success of the initiated treatment and patient participation in the decision of the treatment plan can be implemented. The second-level approach ideally involves strategies to prevent progression of disease, in addition to prediction of success of therapy, and patient participation in the long-term therapeutic strategy. Endotype-driven treatment is part of a personalized approach and should be positioned at the tertiary level of care, given the efforts needed for its implementation and the high cost of molecular diagnosis and biological treatment.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Schlagworte: allergic rhiniti; integrated care pathway; precision medicine; rhinosinusitis
  17. European Specifications for Value-based Pre-Commercial Procurement of Innovative ICT for Empowerment and Self-management of Diabetes Mellitus Patients
    Autor*in: De Luca V.; Birov S.; Beyhan O.; Robinson S.; Sanchez-Nanclares G.; Del Pilar L�pez Acu�a M.; Fernandes A.; Hammerschmidt R.; Annuzzi G.; Iaccarino G.; Illario M.
    Erschienen: 2019

    Current demographic changes require a paradigm shift in the delivery of health and social services. Wide-scale implementation of validated ICT support to clinicians and patients is essential to ensure the quality of services to future generations of... mehr

     

    Current demographic changes require a paradigm shift in the delivery of health and social services. Wide-scale implementation of validated ICT support to clinicians and patients is essential to ensure the quality of services to future generations of citizens. Healthcare providers from four European regions - Turkey, Portugal, Campania and Murcia- have joined forces to procure an innovative ICT solution for patient empowerment and self-management for patients with diabetes mellitus. The procurement is in the form of a joint pre-commercial procurement (PCP) of Research & Development, with participation by EU industry in competitive phases of development. The PCP is part of the EU-funded project ProEmpower, which is currently in the prototype testing phase. The challenge faced by the procurers was to jointly define specifications for the envisioned solution that reflect the needs of all four regions. After an intensive year of consultations with procurers' experts - clinicians, IT staff, procurement specialists - ProEmpower launched a call for tender with the defined specifications, which reflect the unmet needs across the procuring regions with regards to improving management of diabetes mellitus supported by ICT. This paper presents the ProEmpower specifications, which can be easily adapted to the local conditions of any procuring region in Europe and beyond. The specifications thus represent a valuable source for any new development of ICT-supported diabetes management.

     
    Export in Literaturverwaltung
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Konferenzveröffentlichung
    Format: Online
    Schlagworte: Diabetes Mellitu; ICT; Management; Pre-Commercial Procurement; Technical Specifications
  18. The Italian reference sites of the European innovation partnership on active and healthy ageing: Progetto Mattone Internazionale as an enabling factor
    Autor*in: Illario M.; De Luca V.; Tramontano G.; Menditto E.; Iaccarino G.; Bertorello L.; Palummeri E.; Romano V.; Moda G.; Maggio M.; Barbolini M.; Leonardini L.; Addis A.
    Erschienen: 2017

  19. Aging and metabolic syndrome: Common molecular pathways
    Autor*in: Illario M.
    Erschienen: 2016

    Zitierfähiger Link:
    http://hdl.handle.net/11588/826710
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
  20. Healthcare recommendations from the personalised ict supported service for independent living and active ageing (PERSSILAA) study
    Autor*in: O'Caoimh R.; Molloy D. W.; Fitzgerald C.; Van Velsen L.; Cabrita M.; Nassabi M. H.; De Vette F.; Weering M. D. -V.; Jansen-Kosterink S.; Kenter W.; Frazer S.; Rauter A. P.; Turkman A.; Antunes M.; Turkman F.; Silva M. S.; Martins A.; Costa H. S.; Albuquerque T. G.; Ferreira A.; Scherillo M.; De Luca V.; Illario M.; Garcia-Rudolph A.; Sanchez-Carrion R.; Sanchez J. S.; Aguilera E. J. G.; Hermens H.; Vollenbroek-Hutten M.
    Erschienen: 2017

    In the face of demographic ageing European healthcare providers and policy makers are recognising an increasing prevalence of frail, community-dwelling older adults, prone to adverse healthcare outcomes. Prefrailty, before onset of functional... mehr

     

    In the face of demographic ageing European healthcare providers and policy makers are recognising an increasing prevalence of frail, community-dwelling older adults, prone to adverse healthcare outcomes. Prefrailty, before onset of functional decline, is suggested to be reversible but interventions targeting this risk syndrome are limited. No consensus on the definition, diagnosis or management of pre-frailty exists. The PERsonalised ICT Supported Service for Independent Living and Active Ageing (PERSSILAA) project (2013-2016 under Framework Programme 7, grant #610359) developed a comprehensive Information and Communication Technologies (ICT) supported platform to screen, assess, manage and monitor pre-frail community-dwelling older adults in order to address pre-frailty and promote active and healthy ageing. PERSSILAA, a multi-domain ICT service, targets three pre-frailty: nutrition, cognition and physical function. The project produced 42 recommendations across clinical (screening, monitoring and managing of pre-frail older adults) technical (ICT-based innovations) and societal (health literacy in older adults, guidance to healthcare professional, patients, caregivers and policy makers) areas. This paper describes the 25 healthcare related recommendations of PERSSILAA, exploring how they could be used in the development of future European guidelines on the screening and prevention of frailty.

     
    Export in Literaturverwaltung
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Konferenzveröffentlichung
    Format: Online
    Schlagworte: Clinical; Frailty; Guideline; Healthcare recommendation; Information and communication technology; Pre-frailty