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  1. Can integrated care help in meeting the challenges posed on our health care systems by COVID-19? Some preliminary lessons learned from the european VIGOUR project
    Autor*in: Lindner S.; Kubitschke L.; Lionis C.; Anastasaki M.; Kirchmayer U.; Giacomini S.; De Luca V.; Iaccarino G.; Illario M.; Maddalena A.; Maritati A.; Conforti D.; Roba I.; Musian D.; Cano A.; Granell M.; Carriazo A. M.; Lama C. M.; Rodriguez S.; Guligowska A.; Kostka T.; Konijnendijk A.; Vitullo M.; Garcia-Rudolph A.; Sanchez J. S.; Maggio M.; Liotta G.; Tziraki C.; Roller-Wirnsberger R.
    Erschienen: 2020

    The COVID-19 pandemic puts health and care systems under pressure globally. This current paper highlights challenges arising in the care for older and vulnerable populations in this context and reflects upon possible perspectives for different... mehr

     

    The COVID-19 pandemic puts health and care systems under pressure globally. This current paper highlights challenges arising in the care for older and vulnerable populations in this context and reflects upon possible perspectives for different systems making use of nested integrated care approaches adapted during the work of the EU-funded project VIGOUR (“Evidence based Guidance to Scale-up Integrated Care in Europe”, funded by the European Union’s Health Programme 2014–2020 under Grant Agreement Number 826640).

     
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    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Schlagworte: Health care; Integrated care; Pandemic management; Social care; Vulnerable patients
    Lizenz:

    info:eu-repo/semantics/openAccess
  2. Next-generation care pathways for allergic rhinitis and asthma multimorbidity: A model for multimorbid non-communicable diseases—Meeting Report (Part 2)
    Autor*in: Bousquet J.; Pham-Thi N.; Bedbrook A.; Agache I.; Annesi-Maesano I.; Ansotegui I.; Anto J. M.; Bachert C.; Benveniste S.; Bewick M.; Billo N.; Bosnic-Anticevich S.; Bosse I.; Brusselle G.; Calderon M. A.; Canonica G. W.; Caraballo L.; Cardona V.; Carriazo A. M.; Cash E.; Cecchi L.; Chu D. K.; Colgan E.; Costa E.; Cruz A. A.; Czarlewski W.; Durham S.; Ebisawa M.; Erhola M.; Fauquert J. -L.; Fokkens W. J.; Fonseca J. A.; Guldemond N.; Iinuma T.; Illario M.; Klimek L.; Kuna P.; Kvedariene V.; Larenas-Linneman D.; Laune D.; Le L. T. T.; Lourenco O.; Malva J. O.; Marien G.; Menditto E.; Mullol J.; Munter L.; Okamoto Y.; Onorato G. L.; Papadopoulos N. G.; Perala M.; Pfaar O.; Phillips A.; Phillips J.; Pinnock H.; Portejoie F.; Quinones-Delgado P.; Rolland C.; Rodts U.; Samolinski B.; Sanchez-Borges M.; Schunemann H. J.; Shamji M.; Somekh D.; Togias A.; Toppila-Salmi S.; Tsiligianni I.; Usmani O.; Walker S.; Wallace D.; Valiulis A.; Van der Kleij R.; Ventura M. T.; Williams S.; Yorgancioglu A.; Zuberbier T.
    Erschienen: 2019

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    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
  3. Transitional palliative care interventions for older adults with advanced non-malignant diseases and frailty: a systematic review
    Autor*in: Sezgin D.; Hendry A.; Liew A.; O'Donovan M.; Salem M.; Carriazo A. M.; Lopez-Samaniego L.; Rodriguez-Acuna R.; Kennelly S.; Illario M.; Arnal Carda C.; Inzitari M.; Hammar T.; O'Caoimh R.
    Erschienen: 2020

    Purpose: To identify transitional palliative care (TPC) interventions for older adults with non-malignant chronic diseases and complex conditions. Design/methodology/approach: A systematic review of the literature was conducted. CINAHL, Cochrane... mehr

     

    Purpose: To identify transitional palliative care (TPC) interventions for older adults with non-malignant chronic diseases and complex conditions. Design/methodology/approach: A systematic review of the literature was conducted. CINAHL, Cochrane Library, Embase and Pubmed databases were searched for studies reporting TPC interventions for older adults, published between 2002 and 2019. The Crowe Critical Appraisal Tool was used for quality appraisal. Findings: A total of six studies were included. Outcomes related to TPC interventions were grouped into three categories: healthcare system-related outcomes (rehospitalisation, length of stay [LOS] and emergency department [ED] visits), patient-related outcomes and family/carer important outcomes. Overall, TPC interventions were associated with lower readmission rates and LOS, improved quality of life and better decision-making concerning hospice care among families. Outcomes for ED visits were unclear. Research limitations/implications: Positive outcomes related to healthcare services (including readmissions and LOS), patients (quality of life) and families (decision-making) were reported. However, the number of studies supporting the evidence were limited. Originality/value: Studies examining the effectiveness of existing care models to support transitions for those in need of palliative care are limited. This systematic literature review identified and appraised interventions aimed at improving transitions to palliative care in older adults with advanced non-malignant diseases or frailty.

     
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    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Schlagworte: Advanced disease; Care model; Chronic disease; End-of-life care; Frailty; Non-malignant; Older adult; Palliative care; Transitional care
    Lizenz:

    info:eu-repo/semantics/openAccess
  4. European Summit on the Prevention and Self-Management of Chronic Respiratory Diseases: Report of the European Union Parliament Summit (29 March 2017)
    Autor*in: Hellings P. W.; Borrelli D.; Pietikainen S.; Agache I.; Akdis C.; Bachert C.; Bewick M.; Botjes E.; Constantinidis J.; Fokkens W.; Haahtela T.; Hopkins C.; Illario M.; Joos G.; Lund V.; Muraro A.; Pugin B.; Seys S.; Somekh D.; Stjarne P.; Valiulis A.; Valovirta E.; Bousquet J.
    Erschienen: 2017

    On March 29, 2017, a European Summit on the Prevention and Self-Management of Chronic Respiratory Diseases (CRD) was organized by the European Forum for Research and Education in Allergy and Airway Diseases. The event took place in the European... mehr

     

    On March 29, 2017, a European Summit on the Prevention and Self-Management of Chronic Respiratory Diseases (CRD) was organized by the European Forum for Research and Education in Allergy and Airway Diseases. The event took place in the European Parliament of Brussels and was hosted by MEP David Borrelli and MEP Sirpa Pietikainen. The aim of the Summit was to correspond to the needs of the European Commission and of patients suffering from CRD to join forces in Europe for the prevention and self-management. Delegates of the European Rhinologic Society, European Respiratory Society, European Academy of Allergy and Clinical Immunology, European Academy of Paediatrics, and European Patients Organization EFA all lectured on their vision and action plan to join forces in achieving adequate prevention and self-management of CRD in the context of Precision Medicine. Recent data highlight the preventive capacity of education on optimal care pathways for CRD. Self-management and patient empowerment can be achieved by novel educational on-line materials and by novel mobile health tools enabling patients and doctors to monitor and optimally treat CRDs based on the level of control. This report summarizes the contributions of the representatives of different European academic stakeholders in the field of CRD.

     
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    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Schlagworte: Advocacy; Allergy; Asthma; EUFOREA; Mobile health technology
  5. Correlation between work impairment, scores of rhinitis severity and asthma using the MASK-air® App
    Autor*in: Bedard A.; Anto J. M.; Fonseca J. A.; Arnavielhe S.; Bachert C.; Bedbrook A.; Bindslev-Jensen C.; Bosnic-Anticevich S.; Cardona V.; Cruz A. A.; Fokkens W. J.; Garcia-Aymerich J.; Hellings P. W.; Ivancevich J. C.; Klimek L.; Kuna P.; Kvedariene V.; Larenas-Linnemann D.; Melen E.; Monti R.; Mosges R.; Mullol J.; Papadopoulos N. G.; Pham-Thi N.; Samolinski B.; Tomazic P. V.; Toppila-Salmi S.; Ventura M. T.; Yorgancioglu A.; Bousquet J.; Pfaar O.; Basagana X.; Aberer W.; Agache I.; Akdis C. A.; Akdis M.; Aliberti M. R.; Almeida R.; Amat F.; Angles R.; Annesi-Maesano I.; Ansotegui I. J.; Arnavielle S.; Asayag E.; Asarnoj A.; Arshad H.; Avolio F.; Bacci E.; Baiardini I.; Barbara C.; Barbagallo M.; Baroni I.; Barreto B. A.; Bateman E. D.; Bedolla-Barajas M.; Bewick M.; Beghe B.; Bel E. H.; Bergmann K. C.; Bennoor K. S.; Benson M.; Bertorello L.; Bialoszewski A. Z.; Bieber T.; Bialek S.; Bjermer L.; Blain H.; Blasi F.; Blua A.; Bochenska Marciniak M.; Bogus-Buczynska I.; Boner A. L.; Bonini M.; Bonini S.; Bosse I.; Bouchard J.; Boulet L. P.; Bourret R.; Bousquet P. J.; Braido F.; Briedis V.; Brightling C. E.; Brozek J.; Bucca C.; Buhl R.; Buonaiuto R.; Panaitescu C.; Burguete Cabanas M. T.; Burte E.; Bush A.; Caballero-Fonseca F.; Caillaud D.; Caimmi D.; Calderon M. A.; Camargos P. A. M.; Camuzat T.; Canfora G.; Canonica G. W.; Carlsen K. H.; Carreiro-Martins P.; Carriazo A. M.; Carr W.; Cartier C.; Casale T.; Castellano G.; Cecchi L.; Cepeda A. M.; Chavannes N. H.; Chen Y.; Chiron R.; Chivato T.; Chkhartishvili E.; Chuchalin A. G.; Chung K. F.; Ciaravolo M. M.; Ciceran A.; Cingi C.; Ciprandi G.; Carvalho Coehlo A. C.; Colas L.; Colgan E.; Coll J.; Conforti D.; Constantinidis J.; Correia de Sousa J.; Cortes-Grimaldo R. M.; Corti F.; Costa E.; Costa-Dominguez M. C.; Courbis A. L.; Cox L.; Crescenzo M.; Custovic A.; Czarlewski W.; Dahlen S. E.; D'Amato G.; Dario C.; da Silva J.; Dauvilliers Y.; Darsow U.; De Blay F.; De Carlo G.; Dedeu T.; de Fatima Emerson M.; De Feo G.; De Vries G.; De Martino B.; Motta Rubini N. P.; Deleanu D.; Denburg J. A.; Devillier P.; Di Capua Ercolano S.; Di Carluccio N.; Didier A.; Dokic D.; Dominguez-Silva M. G.; Douagui H.; Dray G.; Dubakiene R.; Durham S. R.; Du Toit G.; Dykewicz M. S.; El-Gamal Y.; Eklund P.; Eller E.; Emuzyte R.; Farrell J.; Farsi A.; Ferreira de Mello J.; Ferrero J.; Fink-Wagner A.; Fiocchi A.; Fontaine J. F.; Forti S.; Fuentes-Perez J. M.; Galvez-Romero J. L.; Gamkrelidze A.; Garcia-Cobas C. Y.; Garcia-Cruz M. H.; Gemicioglu B.; Genova S.; Christoff G.; Gereda J. E.; Gerth van Wijk R.; Gomez R. M.; Gomez-Vera J.; Gonzalez Diaz S.; Gotua M.; Grisle I.; Guidacci M.; Guldemond N. A.; Gutter Z.; Guzman M. A.; Haahtela T.; Hajjam J.; Hernandez L.; Hourihane J. O. '. B.; Huerta-Villalobos Y. R.; Humbert M.; Iaccarino G.; Illario M.; Ispayeva Z.; Jares E. J.; Jassem E.; Johnston S. L.; Joos G.; Jung K. S.; Just J.; Jutel M.; Kaidashev I.; Kalayci O.; Kalyoncu A. F.; Karjalainen J.; Kardas P.; Keil T.; Keith P. K.; Khaitov M.; Khaltaev N.; Kleine-Tebbe J.; Kowalski M. L.; Kuitunen M.; Kull I.; Kupczyk M.; Krzych-Falta E.; Lacwik P.; Laune D.; Lauri D.; Lavrut J.; Le L. T. T.; Lessa M.; Levato G.; Li J.; Lieberman P.; Lipiec A.; Lipworth B.; Lodrup Carlsen K. C.; Louis R.; Lourenco O.; Luna-Pech J. A.; Magnan A.; Mahboub B.; Maier D.; Mair A.; Majer I.; Malva J.; Mandajieva E.; Manning P.; De Manuel Keenoy E.; Marshall G. D.; Masjedi M. R.; Maspero J. F.; Mathieu-Dupas E.; Matta Campos J. J.; Matos A. L.; Maurer M.; Mavale-Manuel S.; Mayora O.; Meco C.; Medina-Avalos M. A.; Melo-Gomes E.; Meltzer E. O.; Menditto E.; Mercier J.; Miculinic N.; Mihaltan F.; Milenkovic B.; Moda G.; Mogica-Martinez M. D.; Mohammad Y.; Momas I.; Montefort S.; Mora Bogado D.; Morais-Almeida M.; Morato-Castro F. F.; Mota-Pinto A.; Moura Santo P.; Munter L.; Muraro A.; Murray R.; Naclerio R.; Nadif R.; Nalin M.; Napoli L.; Namazova-Baranova L.; Neffen H.; Niedeberger V.; Nekam K.; Neou A.; Nieto A.; Nogueira-Silva L.; Nogues M.; Novellino E.; Nyembue T. D.; O'Hehir R. E.; Odzhakova C.; Ohta K.; Okamoto Y.; Okubo K.; Onorato G. L.; Ortega Cisneros M.; Ouedraogo S.; Pali-Scholl I.; Palkonen S.; Panzner P.; Park H. S.; Papi A.; Passalacqua G.; Paulino E.; Pawankar R.; Pedersen S.; Pepin J. L.; Pereira A. M.; Persico M.; Phillips J.; Picard R.; Pigearias B.; Pin I.; Pitsios C.; Plavec D.; Pohl W.; Popov T. A.; Portejoie F.; Potter P.; Pozzi A. C.; Price D.; Prokopakis E. P.; Puy R.; Pugin B.; Pulido Ross R. E.; Przemecka M.; Rabe K. F.; Raciborski F.; Rajabian-Soderlund R.; Reitsma S.; Ribeirinho I.; Rimmer J.; Rivero-Yeverino D.; Rizzo J. A.; Rizzo M. C.; Robalo-Cordeiro C.; Rodenas F.; Rodo X.; Rodriguez Gonzalez M.; Rodriguez-Manas L.; Rolland C.; Rodrigues Valle S.; Roman Rodriguez M.; Romano A.; Rodriguez-Zagal E.; Rolla G.; Roller-Wirnsberger R. E.; Romano M.; Rosado-Pinto J.; Rosario N.; Rottem M.; Ryan D.; Sagara H.; Salimaki J.; Sanchez-Borges M.; Sastre-Dominguez J.; Scadding G. K.; Schunemann H. J.; Scichilone N.; Schmid-Grendelmeier P.; Sarquis Serpa F.; Shamai S.; Sheikh A.; Sierra M.; Simons F. E. R.; Siroux V.; Sisul J. C.; Skrindo I.; Sole D.; Somekh D.; Sondermann M.; Sooronbaev T.; Sova M.; Sorensen M.; Sorlini M.; Spranger O.; Stellato C.; Stelmach R.; Stukas R.; Sunyer J.; Strozek J.; Szylling A.; Tebyrica J. N.; Thibaudon M.; To T.; Todo-Bom A.; Trama U.; Triggiani M.; Suppli Ulrik C.; Urrutia-Pereira M.; Valenta R.; Valero A.; Valiulis A.; Valovirta E.; van Eerd M.; van Ganse E.; van Hage M.; Vandenplas O.; Vezzani G.; Vasankari T.; Vatrella A.; Verissimo M. T.; Viart F.; Viegi G.; Vicheva D.; Vontetsianos T.; Wagenmann M.; Walker S.; Wallace D.; Wang D. Y.; Waserman S.; Werfel T.; Westman M.; Wickman M.; Williams D. M.; Williams S.; Wilson N.; Wright J.; Wroczynski P.; Yakovliev P.; Yawn B. P.; Yiallouros P. K.; Yusuf O. M.; Zar H. J.; Zhang L.; Zhong N.; Zernotti M. E.; Zhanat I.; Zidarn M.; Zuberbier T.; Zubrinich C.; Zurkuhlen A.
    Erschienen: 2020

    Background: In allergic rhinitis, a relevant outcome providing information on the effectiveness of interventions is needed. In MASK-air (Mobile Airways Sentinel Network), a visual analogue scale (VAS) for work is used as a relevant outcome. This... mehr

     

    Background: In allergic rhinitis, a relevant outcome providing information on the effectiveness of interventions is needed. In MASK-air (Mobile Airways Sentinel Network), a visual analogue scale (VAS) for work is used as a relevant outcome. This study aimed to assess the performance of the work VAS work by comparing VAS work with other VAS measurements and symptom-medication scores obtained concurrently. Methods: All consecutive MASK-air users in 23 countries from 1 June 2016 to 31 October 2018 were included (14 189 users; 205 904 days). Geolocalized users self-assessed daily symptom control using the touchscreen functionality on their smart phone to click on VAS scores (ranging from 0 to 100) for overall symptoms (global), nose, eyes, asthma and work. Two symptom-medication scores were used: the modified EAACI CSMS score and the MASK control score for rhinitis. To assess data quality, the intra-individual response variability (IRV) index was calculated. Results: A strong correlation was observed between VAS work and other VAS. The highest levels for correlation with VAS work and variance explained in VAS work were found with VAS global, followed by VAS nose, eye and asthma. In comparison with VAS global, the mCSMS and MASK control score showed a lower correlation with VAS work. Results are unlikely to be explained by a low quality of data arising from repeated VAS measures. Conclusions: VAS work correlates with other outcomes (VAS global, nose, eye and asthma) but less well with a symptom-medication score. VAS work should be considered as a potentially useful AR outcome in intervention studies.

     
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    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Schlagworte: asthma; MASK; rhiniti; score; visual analogue scale
    Lizenz:

    info:eu-repo/semantics/openAccess
  6. Next-generation care pathways for allergic rhinitis and asthma multimorbidity: A model for multimorbid non-communicable diseases—Meeting Report (Part 1)
    Autor*in: Bousquet J.; Pham-Thi N.; Bedbrook A.; Agache I.; Annesi-Maesano I.; Ansotegui I.; Anto J. M.; Bachert C.; Benveniste S.; Bewick M.; Billo N.; Bosnic-Anticevich S.; Bosse I.; Brusselle G.; Calderon M. A.; Canonica G. W.; Caraballo L.; Cardona V.; Carriazo A. M.; Cash E.; Cecchi L.; Chu D. K.; Colgan E.; Costa E.; Cruz A. A.; Czarlewski W.; Durham S.; Ebisawa M.; Erhola M.; Fauquert J. -L.; Fokkens W. J.; Fonseca J. A.; Guldemond N.; Iinuma T.; Illario M.; Klimek L.; Kuna P.; Kvedariene V.; Larenas-Linneman D.; Laune D.; Le L. T. T.; Lourenco O.; Malva J. O.; Marien G.; Menditto E.; Mullol J.; Munter L.; Okamoto Y.; Onorato G. L.; Papadopoulos N. G.; Perala M.; Pfaar O.; Phillips A.; Phillips J.; Pinnock H.; Portejoie F.; Quinones-Delgado P.; Rolland C.; Rodts U.; Samolinski B.; Sanchez-Borges M.; Schunemann H. J.; Shamji M.; Somekh D.; Togias A.; Toppila-Salmi S.; Tsiligianni I.; Usmani O.; Walker S.; Wallace D.; Valiulis A.; Van Der Kleij R.; Ventura M. T.; Williams S.; Yorgancioglu A.; Zuberbier T.
    Erschienen: 2019

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    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
  7. Cabbage and fermented vegetables: From death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID-19
    Autor*in: Bousquet J.; Anto J. M.; Czarlewski W.; Haahtela T.; Fonseca S. C.; Iaccarino G.; Blain H.; Vidal A.; Sheikh A.; Akdis C. A.; Zuberbier T.; Hamzah Abdul Latiff A.; Abdullah B.; Aberer W.; Abusada N.; Adcock I.; Afani A.; Agache I.; Aggelidis X.; Agustin J.; Akdis M.; Al-Ahmad M.; Al-Zahab Bassam A.; Alburdan H.; Aldrey-Palacios O.; Alvarez Cuesta E.; Alwan Salman H.; Alzaabi A.; Amade S.; Ambrocio G.; Angles R.; Annesi-Maesano I.; Ansotegui I. J.; Anto J.; Ara Bardajo P.; Arasi S.; Arshad H.; Cristina Artesani M.; Asayag E.; Avolio F.; Azhari K.; Bachert C.; Bagnasco D.; Baiardini I.; Bajrovic N.; Bakakos P.; Bakeyala Mongono S.; Balotro-Torres C.; Barba S.; Barbara C.; Barbosa E.; Barreto B.; Bartra J.; Bateman E. D.; Battur L.; Bedbrook A.; Bedolla Barajas M.; Beghe B.; Bekere A.; Bel E.; Ben Kheder A.; Benson M.; Berghea E. C.; Bergmann K. -C.; Bernardini R.; Bernstein D.; Bewick M.; Bialek S.; Bialoszewski A.; Bieber T.; Billo N. E.; Bilo M. B.; Bindslev-Jensen C.; Bjermer L.; Bobolea I.; Bochenska Marciniak M.; Bond C.; Boner A.; Bonini M.; Bonini S.; Bosnic-Anticevich S.; Bosse I.; Botskariova S.; Bouchard J.; Boulet L. -P.; Bourret R.; Bousquet P.; Braido F.; Briggs A.; Brightling C. E.; Brozek J.; Brussino L.; Buhl R.; Bumbacea R.; Buquicchio R.; Burguete Cabanas M. -T.; Bush A.; Busse W. W.; Buters J.; Caballero-Fonseca F.; Calderon M. A.; Calvo M.; Camargos P.; Camuzat T.; Canevari F. R.; Cano A.; Canonica G. W.; Capriles-Hulett A.; Caraballo L.; Cardona V.; Carlsen K. -H.; Carmon Pirez J.; Caro J.; Carr W.; Carreiro-Martins P.; Carreon-Asuncion F.; Carriazo A. -M.; Casale T.; Castor M. -A.; Castro E.; Caviglia A. G.; Cecchi L.; Cepeda Sarabia A.; Chandrasekharan R.; Chang Y. -S.; Chato-Andeza V.; Chatzi L.; Chatzidaki C.; Chavannes N. H.; Chaves Loureiro C.; Chelninska M.; Chen Y.; Cheng L.; Chinthrajah S.; Chivato T.; Chkhartishvili E.; Christoff G.; Chrystyn H.; Chu D. K.; Chua A.; Chuchalin A.; Chung K. F.; Ciceran A.; Cingi C.; Ciprandi G.; Cirule I.; Coelho A. C.; Compalati E.; Constantinidis J.; Correia de Sousa J.; Costa E. M.; Costa D.; Costa Dominguez M. D. C.; Coste A.; Cottini M.; Cox L.; Crisci C.; Crivellaro M. A.; Cruz A. A.; Cullen J.; Custovic A.; Cvetkovski B.; D'Amato G.; da Silva J.; Dahl R.; Dahlen S. -E.; Daniilidis V.; DarjaziniNahhas L.; Darsow U.; Davies J.; de Blay F.; De Feo G.; De Guia E.; de los Santos C.; De Manuel Keenoy E.; De Vries G.; Deleanu D.; Demoly P.; Denburg J.; Devillier P.; Didier A.; Dimic Janjic S.; Dimou M.; Dinh-Xuan A. T.; Djukanovic R.; Do Ceu Texeira M.; Dokic D.; Dominguez Silva M. G.; Douagui H.; Douladiris N.; Doulaptsi M.; Dray G.; Dubakiene R.; Dupas E.; Durham S.; Duse M.; Dykewicz M.; Ebo D.; Edelbaher N.; Eiwegger T.; Eklund P.; El-Gamal Y.; El-Sayed Z. A.; El-Sayed S. S.; El-Seify M.; Emuzyte R.; Enecilla L.; Erhola M.; Espinoza H.; Espinoza Contreras J. G.; Farrell J.; Fernandez L.; Fink Wagner A.; Fiocchi A.; Fokkens W. J.; Lenia F.; Fonseca J. A.; Fontaine J. -F.; Forastiere F.; Fuentes Perez J. M.; Gaerlan-Resureccion E.; Gaga M.; Galvez Romero J. L.; Gamkrelidze A.; Garcia A.; Garcia Cobas C. Y.; Garcia Cruz M. D. L. L. H.; Gayraud J.; Gelardi M.; Gemicioglu B.; Gennimata D.; Genova S.; Gereda J.; Gerth van Wijk R.; Giuliano A.; Gomez M.; Gonzalez Diaz S.; Gotua M.; Grigoreas C.; Grisle I.; Gualteiro L.; Guidacci M.; Guldemond N.; Gutter Z.; Guzman A.; Halloum R.; Halpin D.; Hamelmann E.; Hammadi S.; Harvey R.; Heffler E.; Heinrich J.; Hejjaoui A.; Hellquist-Dahl B.; Hernandez Velazquez L.; Hew M.; Hossny E.; Howarth P.; Hrubisko M.; Huerta Villalobos Y. R.; Humbert M.; Salina H.; Hyland M.; Ibrahim M.; Ilina N.; Illario M.; Incorvaia C.; Infantino A.; Irani C.; Ispayeva Z.; Ivancevich J. -C.; E. J. Jares E.; Jarvis D.; Jassem E.; Jenko K.; Jimeneracruz Uscanga R. D.; Johnston S. L.; Joos G.; Jost M.; Julge K.; Jung K. -S.; Just J.; Jutel M.; Kaidashev I.; Kalayci O.; Kalyoncu F.; Kapsali J.; Kardas P.; Karjalainen J.; Kasala C. A.; Katotomichelakis M.; Kavaliukaite L.; Kazi B. S.; Keil T.; Keith P.; Khaitov M.; Khaltaev N.; Kim Y. -Y.; Kirenga B.; Kleine-Tebbe J.; Klimek L.; Koffi N'Goran B.; Kompoti E.; Kopac P.; Koppelman G.; KorenJeverica A.; Koskinen S.; Kosnik M.; Kostov K. V.; Kowalski M. L.; Kralimarkova T.; Kramer Vrscaj K.; Kraxner H.; Kreft S.; Kritikos V.; Kudlay D.; Kuitunen M.; Kull I.; Kuna P.; Kupczyk M.; Kvedariene V.; Kyriakakou M.; Lalek N.; Landi M.; Lane S.; Larenas-Linnemann D.; Lau S.; Laune D.; Lavrut J.; Le L.; Lenzenhuber M.; Lessa M.; Levin M.; Li J.; Lieberman P.; Liotta G.; Lipworth B.; Liu X.; Lobo R.; Lodrup Carlsen K. C.; Lombardi C.; Louis R.; Loukidis S.; Lourenco O.; Luna Pech J. A.; Madjar B.; Maggi E.; Magnan A.; Mahboub B.; Mair A.; Mais Y.; Maitland van der Zee A. -H.; Makela M.; Makris M.; Malling H. -J.; Mandajieva M.; Manning P.; Manousakis M.; Maragoudakis P.; Marseglia G.; Marshall G.; Reza Masjedi M.; Maspero J. F.; Matta Campos J. J.; Maurer M.; Mavale-Manuel S.; Meco C.; Melen E.; Melioli G.; Melo-Gomes E.; Meltzer E. O.; Menditto E.; Menzies-Gow A.; Merk H.; Michel J. -P.; Micheli Y.; Miculinic N.; Midao L.; Mihaltan F.; Mikos N.; Milanese M.; Milenkovic B.; Mitsias D.; Moalla B.; Moda G.; Mogica Martinez M. D.; Mohammad Y.; Moin M.; Molimard M.; Momas I.; Mommers M.; Monaco A.; Montefort S.; Mora D.; Morais-Almeida M.; Mosges R.; Mostafa B.; Mullol J.; Munter L.; Muraro A.; Murray R.; Musarra A.; Mustakov T.; Naclerio R.; Nadeau K. C.; Nadif R.; Nakonechna A.; Namazova-Baranova L.; Navarro-Locsin G.; Neffen H.; Nekam K.; Neou A.; Nettis E.; Neuberger D.; Nicod L.; Nicola S.; Niederberger-Leppin V.; Niedoszytko M.; Nieto A.; Novellino E.; Nunes E.; Nyembue D.; O'Hehir R.; Odjakova C.; Ohta K.; Okamoto Y.; Okubo K.; Oliver B.; Onorato G. L.; Pia Orru M.; Ouedraogo S.; Ouoba K.; Paggiaro P. L.; Pagkalos A.; Pajno G.; Pala G.; Palaniappan S. P.; Pali-Scholl I.; Palkonen S.; Palmer S.; Panaitescu Bunu C.; Panzner P.; Papadopoulos N. G.; Papanikolaou V.; Papi A.; Paralchev B.; Paraskevopoulos G.; Park H. -S.; Passalacqua G.; Patella V.; Pavord I.; Pawankar R.; Pedersen S.; Peleve S.; Pellegino S.; Pereira A.; Perez T.; Perna A.; Peroni D.; Pfaar O.; Pham-Thi N.; Pigearias B.; Pin I.; Piskou K.; Pitsios C.; Plavec D.; Poethig D.; Pohl W.; Poplas Susic A.; Popov T. A.; Portejoie F.; Potter P.; Poulsen L.; Prados-Torres A.; Prarros F.; Price D.; Prokopakis E.; Puggioni F.; Puig-Domenech E.; Puy R.; Rabe K.; Raciborski F.; Ramos J.; Recto M. T.; Reda S. M.; Regateiro F. S.; Reider N.; Reitsma S.; Repka-Ramirez S.; Ridolo E.; Rimmer J.; Rivero Yeverino D.; Angelo Rizzo J.; Robalo-Cordeiro C.; Roberts G.; Roche N.; Rodriguez Gonzalez M.; Rodriguez Zagal E.; Rolla G.; Rolland C.
    Erschienen: 2021

    Large differences in COVID-19 death rates exist between countries and between regions of the same country. Some very low death rate countries such as Eastern Asia, Central Europe, or the Balkans have a common feature of eating large quantities of... mehr

     

    Large differences in COVID-19 death rates exist between countries and between regions of the same country. Some very low death rate countries such as Eastern Asia, Central Europe, or the Balkans have a common feature of eating large quantities of fermented foods. Although biases exist when examining ecological studies, fermented vegetables or cabbage have been associated with low death rates in European countries. SARS-CoV-2 binds to its receptor, the angiotensin-converting enzyme 2 (ACE2). As a result of SARS-CoV-2 binding, ACE2 downregulation enhances the angiotensin II receptor type 1 (AT1R) axis associated with oxidative stress. This leads to insulin resistance as well as lung and endothelial damage, two severe outcomes of COVID-19. The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is the most potent antioxidant in humans and can block in particular the AT1R axis. Cabbage contains precursors of sulforaphane, the most active natural activator of Nrf2. Fermented vegetables contain many lactobacilli, which are also potent Nrf2 activators. Three examples are: kimchi in Korea, westernized foods, and the slum paradox. It is proposed that fermented cabbage is a proof-of-concept of dietary manipulations that may enhance Nrf2-associated antioxidant effects, helpful in mitigating COVID-19 severity.

     
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    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Schlagworte: cabbage; diet; fermented vegetable; kimchi; Lactobacillu; sulforaphane
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  8. Positioning the principles of precision medicine in care pathways for allergic rhinitis and chronic rhinosinusitis – A EUFOREA-ARIA-EPOS-AIRWAYS ICP statement
    Autor*in: Hellings P. W.; Fokkens W. J.; Bachert C.; Akdis C. A.; Bieber T.; Agache I.; Bernal-Sprekelsen M.; Canonica G. W.; Gevaert P.; Joos G.; Lund V.; Muraro A.; Onerci M.; Zuberbier T.; Pugin B.; Seys S. F.; Bousquet J.; Aberer W.; Akdis M.; Alobid I.; Ankri J.; Annesi-Maesano I.; Ansotegui I. J.; Anto J. M.; Arnavielhe S.; Arshad H.; Asarnoj A.; Avolio F.; Baiardini I.; Barbagallo M.; Barbara C.; Baroody F.; Bateman E. D.; Bedbrook A.; Beghe B.; Bel E. H.; Bennoor K. S.; Benson M.; Bergmann K. C.; Bewick M.; Bialoszewski A. Z.; Bindslev-Jensen C.; Bjermer L.; Blain H.; Blasi F.; Boner A. L.; Bonini M.; Bonini S.; Bosnic-Anticevich S.; Bosse I.; Bouchard J.; Boulet L. P.; Bourret R.; Bousquet P. J.; Braido F.; Briggs A. H.; Brightling C. E.; Brozek J.; Bucca C.; Buhl R.; Bunu C.; Burte E.; Bush A.; Caballero-Fonseca F.; Caimmi D. P.; Calderon M. A.; Camargos P. A.; Camuzat T.; Cardona V.; Carlsen K. H.; Carr W.; Carreiro-Martins P.; Carriazo A. M.; Casale T.; Cepeda Sarabia A. M.; Cervin A.; Cesari M.; Chatzi L.; Chavannes N. H.; Chiron R.; Chivato T.; Chkhartishvili E.; Chuchalin A. G.; Chung K. F.; Ciprandi G.; Cohen N.; Conzalez Diaz S.; Cox L.; Crooks G.; Cruz A. A.; Custovic A.; Dahl R.; Dahlen S. E.; Darsow U.; De Carlo G.; De Manuel Keenoy E.; de Sousa J. C.; De Vries G.; Dedeu T.; Deleanu D.; Demoly P.; Denburg J. A.; Devillier P.; Didier A.; Dinh-Xuan A. T.; Dokic D.; Douagui H.; Douglas R.; Dray G.; Du Toit G.; Dubakiene R.; Durham S. R.; Dykewicz M. S.; Eklund P.; El-Gamal Y.; Ellers E.; Emuzyte R.; Farrell J.; Fink Wagner A.; Fiocchi A.; Fletcher M.; Fonseca J.; Forastiere F.; Gaga M.; Gamkrelidze A.; Gemicioglu B.; Georgalas C.; Gereda J. E.; Goossens H.; Grisle I.; Guldemond N. A.; Gutter Z.; Guzman M. A.; Haahtela T.; Harvey R.; Heinrich J.; Hellquist-Dahl B.; Hopkins C.; Horak F.; Hourihane J. O.; Humbert M.; Hyland M.; Iaccarino G.; Illario M.; Jares E. J.; Jeandel C.; Johnston S. L.; Jonquet O.; Jung K. S.; Just J.; Jutel M.; Kaidashev I. P.; Kalayci O.; Kalogjera L.; Kalyoncu A. F.; Kardas P.; Keil T.; Keith P. K.; Kerkhof M.; Kern B.; Kerstjens H. A.; Khaitov M.; Khaltaev N.; Klimek L.; Kogevinas M.; Kolek V.; Koppelman G. H.; Kowalski M.; Kowalski M. L.; Kuitunen M.; Kull I.; Kuna P.; Kvedariene V.; Lambrecht B.; Larenas-Linnemann D.; Lau S.; Laune D.; Le L. T.; Li J.; Lieberman P.; Lipworth B.; Lodrup Carlsen K. C.; Louis R.; Lund V. J.; Lupinek C.; MacNee W.; Magar Y.; Magnan A.; Mahboub B.; Maier D.; Majer I.; Malva J.; Manning P.; Marshall G. D.; Masjedi M. R.; Mathieu-Dupas E.; Maurer M.; Mavale-Manuel S.; Melen E.; Melo-Gomes E.; Meltzer E. O.; Mercier J.; Merk H.; Miculinic N.; Mihaltan F.; Milenkovic B.; Millot-Keurinck J.; Mohammad Y.; Momas I.; Morais-Almeida M.; Mosges R.; Mullol J.; Murray R.; Naclerio R.; Nadif R.; Namazova-Baranova L.; Neffen H.; Nekam K.; Nieto A.; Nogues M.; Nyembue T. D.; O'Hehir R. E.; Ohta K.; Okamoto Y.; Okubo K.; Olive-Elias M.; Ouedraogo S.; Paggiaro P.; Pali-Scholl I.; Palkonen S.; Panzner P.; Papadopoulos N. G.; Papi A.; Park H. S.; Passalacqua G.; Niggemann B.; Nogueira-Silva L.; Pereira A. M.; Pfaar O.; Picard R.; Pigearias B.; Pin I.; Plavec D.; Pohl W.; Popov T. A.; Portejoie F.; Postma D.; Potter P.; Poulsen L. K.; Price D.; Rabe K. F.; Raciborski F.; Riechelmann H.; Robalo-Cordeiro C.; Roberts G.; Rodenas F.; Rodriguez-Manas L.; Rolland C.; Roman Rodriguez M.; Romano A.; Rosado-Pinto J.; Rosario N.; Rottem M.; Ryan D.; Samolinski B.; Sanchez-Borges M.; Sastre-Dominguez J.; Scadding G. K.; Schlosser R.; Schmid-Grendelmeier P.; Schunemann H. J.; Scichilone N.; Senior B.; Serrano E.; Sheikh A.; Shields M.; Simons F. E. R.; Siroux V.; Sisul J. C.; Skrindo I.; Smit H. A.; Sole D.; Sooronbaev T.; Spranger O.; Stellato C.; Stelmach R.; Sterk P. J.; Strandberg T.; Sunyer J.; Thijs C.; Thomas M.; Todo-Bom A.; Tomazic P. V.; Toskala E.; Triggiani M.; Valenta R.; Valero A.; Valiulis A.; Valovirta E.; van Eerd M.; van Ganse E.; van Hage M.; van Wick R. G.; Vandenplas O.; Varona L. L.; Vazankari T.; Vellas B.; Ventura M. T.; Vezzani G.; Viegi G.; Voegels R.; Vontetsianos T.; Wagenmann M.; Wahn U.; Walker S.; Wang D. Y.; Wang Y.; Werfel T.; Whalley B.; Wickman M.; Williams D. M.; Williams S.; Wilson N.; Wormald P. J.; Wright J.; Yawn B. P.; Yiallouros P. K.; Yorgancioglu A.; Young I.; Yusuf O. M.; Zaidi A.; Zar H. J.; Zernotti M. E.; Zhang L.; Zhong N.; Zidarn M.
    Erschienen: 2017

    Precision medicine (PM) is increasingly recognized as the way forward for optimizing patient care. Introduced in the field of oncology, it is now considered of major interest in other medical domains like allergy and chronic airway diseases, which... mehr

     

    Precision medicine (PM) is increasingly recognized as the way forward for optimizing patient care. Introduced in the field of oncology, it is now considered of major interest in other medical domains like allergy and chronic airway diseases, which face an urgent need to improve the level of disease control, enhance patient satisfaction and increase effectiveness of preventive interventions. The combination of personalized care, prediction of treatment success, prevention of disease and patient participation in the elaboration of the treatment plan is expected to substantially improve the therapeutic approach for individuals suffering from chronic disabling conditions. Given the emerging data on the impact of patient stratification on treatment outcomes, European and American regulatory bodies support the principles of PM and its potential advantage over current treatment strategies. The aim of the current document was to propose a consensus on the position and gradual implementation of the principles of PM within existing adult treatment algorithms for allergic rhinitis (AR) and chronic rhinosinusitis (CRS). At the time of diagnosis, prediction of success of the initiated treatment and patient participation in the decision of the treatment plan can be implemented. The second-level approach ideally involves strategies to prevent progression of disease, in addition to prediction of success of therapy, and patient participation in the long-term therapeutic strategy. Endotype-driven treatment is part of a personalized approach and should be positioned at the tertiary level of care, given the efforts needed for its implementation and the high cost of molecular diagnosis and biological treatment.

     
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    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Schlagworte: allergic rhiniti; integrated care pathway; precision medicine; rhinosinusitis