Direkt zur Hauptnavigation springen Direkt zum Inhalt springen
info(at)avldigital.remove-this.de
Deutsch English
Filtern nach
Aktive Filter
Letzte Suchanfragen

Ergebnisse für *

Zeige Ergebnisse 126 bis 150 von 24992.

  1. Mobile Technology in Allergic Rhinitis: Evolution in Management or Revolution in Health and Care?
    Autor*in: Bousquet J.; Ansotegui I. J.; Anto J. M.; Arnavielhe S.; Bachert C.; Basagana X.; Bedard A.; Bedbrook A.; Bonini M.; Bosnic-Anticevich S.; Braido F.; Cardona V.; Czarlewski W.; Cruz A. A.; Demoly P.; De Vries G.; Dramburg S.; Mathieu-Dupas E.; Erhola M.; Fokkens W. J.; Fonseca J. A.; Haahtela T.; Hellings P. W.; Illario M.; Ivancevich J. C.; Jormanainen V.; Klimek L.; Kuna P.; Kvedariene V.; Laune D.; Larenas-Linnemann D.; Lourenco O.; Onorato G. L.; Matricardi P. M.; Melen E.; Mullol J.; Papadopoulos N. G.; Pfaar O.; Pham-Thi N.; Sheikh A.; Tan R.; To T.; Tomazic P. V.; Toppila-Salmi S.; Tripodi S.; Wallace D.; Valiulis A.; van Eerd M.; Ventura M. T.; Yorgancioglu A.; Zuberbier T.
    Erschienen: 2019

    Smart devices and Internet-based applications (apps) are largely used in allergic rhinitis and may help to address some unmet needs. However, these new tools need to first of all be tested for privacy rules, acceptability, usability, and... mehr

     

    Smart devices and Internet-based applications (apps) are largely used in allergic rhinitis and may help to address some unmet needs. However, these new tools need to first of all be tested for privacy rules, acceptability, usability, and cost-effectiveness. Second, they should be evaluated in the frame of the digital transformation of health, their impact on health care delivery, and health outcomes. This review (1) summarizes some existing mobile health apps for allergic rhinitis and reviews those in which testing has been published, (2) discusses apps that include risk factors of allergic rhinitis, (3) examines the impact of mobile health apps in phenotype discovery, (4) provides real-world evidence for care pathways, and finally (5) discusses mobile health tools enabling the digital transformation of health and care, empowering citizens, and building a healthier society.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Schlagworte: App; Digital transformation of health; MASK; mHealth; Mobile technology; Rhiniti; Delivery of Health Care; Europe; Human; Mobile Application; Phenotype; Rhinitis; Allergic; Risk Factor; Telemedicine; Smartphone
  2. Dietary polyphenols and type 2 diabetes: Human Study and Clinical Trial
    Autor*in: Cao H.; Ou J.; Chen L.; Zhang Y.; Szkudelski T.; Delmas D.; Daglia M.; Xiao J.
    Erschienen: 2019

    Significant evidence from epidemiological investigations showed that dietary polyphenols might manage and prevent type 2 diabetes (T2D). This review summarizes human studies and clinical trials of polyphenols as anti-diabetic agents. Polyphenols from... mehr

     

    Significant evidence from epidemiological investigations showed that dietary polyphenols might manage and prevent type 2 diabetes (T2D). This review summarizes human studies and clinical trials of polyphenols as anti-diabetic agents. Polyphenols from coffee, guava tea, whortleberry, olive oil, propolis, chocolate, red wine, grape seed, and cocoa have been reported to show anti-diabetic effects in T2D patients through increasing glucose metabolism, improving vascular function as well as reducing insulin resistance and HbA1c level. However, individual flavonoid or isoflavonoid compounds appear to have no therapeutic effect on diabetes, based on the limited clinical data. Preliminary clinical trials provided evidence that resveratrol had anti-diabetic activity in humans by improving glycemic control in subjects with insulin resistance. Besides, anthocyanins exhibited anti-diabetic properties by reducing blood glucose and HbA1c levels or the improvement of insulin secretion and resistance. The structure-activity relationship of polyphenols as anti-diabetic agents in humans has been rarely reported.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Schlagworte: clinical trial; Dietary polyphenol; human Study; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Human; Hypoglycemic Agent; Polyphenol; Diet; Insulin Resistance
  3. Shedding light on the migratory patterns of the Amazonian goliath catfish, Brachyplatystoma platynemum , using otolith 87 Sr/ 86 Sr analyses
    Autor*in: Hauser, Marilia; Doria, Carolina R.C.; Santos, Roberto; García-Vasquez, Aurea; Pouilly, Marc; Pécheyran, Christophe; Ponzevera, Emmanuel; Torrente-Vilara, Gislene; Bérail, Sylvain; Panfili, Jacques; Darnaude, Audrey,; Renno, Jean-François; García-Dávila, Carmen; Nuñez, Jesus; Ferraton, Franck; Vargas, Gladys; Duponchelle, Fabrice
    Erschienen: 2019
    Verlag:  HAL CCSD ; Wiley

    International audience ; In the Amazon, migratory catfishes of the genus Brachyplatystoma are apex predators that are important for fisheries and conservation. The life cycle of Brachyplatystoma platynemum Boulenger, 1898 is poorly known, although it... mehr

     

    International audience ; In the Amazon, migratory catfishes of the genus Brachyplatystoma are apex predators that are important for fisheries and conservation. The life cycle of Brachyplatystoma platynemum Boulenger, 1898 is poorly known, although it has been hypothesized to be very similar to that of Brachyplatystoma rousseauxii Castelnau, 1855, which uses the entire length of the Amazon basin to complete its life cycle (from the Andes to the estuary). This study provides the first data on the migratory patterns of B. platynemum at the individual level using otolith microchemistry. In total, 94 individuals were sampled close to major breeding areas in the Amazon basin (78 fish from the middle and upper Madeira River and 14 fish from the upper Amazon), and their lifetime movements were assessed by measuring variations in 87 Sr/ 86 Sr along transverse sections of their otoliths (ear stones), using laser ablation multi-collector mass spectrometry (LA-MC-ICP-MS). The migrations of B. platynemum are not as extensive as those of B. rousseauxii, and do not involve natal homing. Furthermore, the estuary is not a nursery area, at least for fish hatched in the Madeira. Nevertheless, B. platynemum migrates several thousand kilometres within the Amazon basin, with transboundary displacements between at least Bolivia, Brazil, and Peru. Current and planned hydroelectric development in the Amazon basin will severely disrupt both migration and access to breeding grounds, ultimately affecting the recruitment and population dynamics of these apex predators. The conservation of B. platynemum is crucial for the stability of the Amazonian aquatic food webs. This requires building effective fish passage on the two existing Madeira dams and considering alternative options to the large-scale hydropower development in the Amazon basin

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Übergeordneter Titel: ISSN: 1052-7613 ; EISSN: 1099-0755 ; Aquatic Conservation: Marine and Freshwater Ecosystems ; https://hal.science/hal-02055491 ; Aquatic Conservation: Marine and Freshwater Ecosystems, 2019, 29 (3), pp.397-408. ⟨10.1002/aqc.3046⟩
    Schlagworte: fish; conservation evaluation; catchment; fishing; hydroelectric dams; migration; river; [CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry; [CHIM.ANAL]Chemical Sciences/Analytical chemistry; [CHIM.POLY]Chemical Sciences/Polymers; [CHIM.MATE]Chemical Sciences/Material chemistry
  4. Multicenter Evaluation of a Novel Immunochromatographic Test for Anti-aspergillus IgG Detection
    Autor*in: Piarroux, Raphael P.; Romain, Thomas; Martin, Aurelie; Vainqueur, Damien; Vitte, Joana; Lachaud, Laurence; Gangneux, Jean-Pierre; Gabriel, Frédéric; Fillaux, Judith; Ranque, Stéphane
    Erschienen: 2019
    Verlag:  HAL CCSD ; Frontiers

    International audience ; Aspergillus sp. fungi cause various diseases in both immunocompetent and immunocompromised patients. The most frequent Aspergillus disorders include chronic pulmonary aspergillosis (CPA), a life-threatening disease that... mehr

     

    International audience ; Aspergillus sp. fungi cause various diseases in both immunocompetent and immunocompromised patients. The most frequent Aspergillus disorders include chronic pulmonary aspergillosis (CPA), a life-threatening disease that affects at least 3 million people worldwide, and allergic bronchopulmonary aspergillosis (ABPA), which affects approximately 4.8 million severe asthmatic patients globally. Diagnosis of such diseases involves IgG serological testing; however, the currently available anti-Aspergillus IgG detection assays are inappropriate for resource-poor laboratory settings, as they are expensive, rely on automated procedures, and require stable electrical power. Therefore, accurate CPA or ABPA diagnosis facilities are lacking in most low- and middle-income countries. We evaluated a novel anti-Aspergillus antibody immunochromatographic test (ICT) that requires minimal laboratory equipment. Two evaluations were performed a single-center 4-month prospective study in a French reference laboratory (44 cases/257 patients) and a retrospective study in five French reference laboratories (262 cases and 188 controls). We estimated the ICT indices for the diagnosis of chronic aspergillosis, and the test results were compared to those of anti-Aspergillus IgG immunoblot (IB) assay. Of the 713 patients included in the study, 306 had chronic aspergillosis. Test sensitivity and specificity were 88.9%(95% CI[85-92]) and 96.3%(95% CI[94-98]) for the ICT and 93.1% (95% CI[90-96]) and 94.3% (95% CI[92-96]) for the IB, respectively. Agreement between the two assays was almost perfect (kappa = 0.86). As this ICT displays good diagnostic performance and complies with the ASSURED (Affordable, Sensitive, Specific, User-friendly, Equipment-free, and Delivered) criteria, we concluded that this anti-Aspergillus antibody ICT can be used to diagnose Aspergillus diseases in resource-poor settings.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Übergeordneter Titel: ISSN: 2235-2988 ; Frontiers in Cellular and Infection Microbiology ; https://hal-univ-rennes1.archives-ouvertes.fr/hal-02061628 ; Frontiers in Cellular and Infection Microbiology, 2019, 9, pp.12. ⟨10.3389/fcimb.2019.00012⟩
    Schlagworte: immunochromatography; allergic broncho-pulmonary aspergillosis; sensitivity; Aspergillus serology; point-of-care; chronic pulmonary aspergillosis; specificity; [SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/Mycology; [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases
    Lizenz:

    creativecommons.org/licenses/by/ ; info:eu-repo/semantics/OpenAccess
  5. Cranial nerve involvement in patients with MOG antibody–associated disease
    Autor*in: Cobo-Calvo, Alvaro; Ayrignac, Xavier; Kerschen, Philippe; Horellou, Philippe; Cotton, François; Labauge, Pierre; Vukusic, Sandra; Deiva, Kumaran; Serguera, Che; Marignier, Romain
    Erschienen: 2019
    Verlag:  HAL CCSD

    International audience mehr

     

    International audience

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Übergeordneter Titel: Neurology - Neuroimmunology Neuroinflammation ; https://hal.science/hal-02063145 ; Neurology - Neuroimmunology Neuroinflammation, 2019, 6 (2), pp.e543. ⟨10.1212/NXI.0000000000000543⟩
    Schlagworte: [SDV]Life Sciences [q-bio]
  6. Comparison of Mycobacterium ulcerans (Buruli ulcer) and Leptospira sp. (Leptospirosis) dynamics in urban and rural settings
    Autor*in: Combe, Marine; Gozlan, Rodolphe Elie; Jagadesh, Soushieta; Velvin, Camilla Jensen; Ruffine, Rolland; Demar, Magalie Pierre; Couppié, Pierre; Djossou, Félix; Nacher, Mathieu; Epelboin, Loïc
    Erschienen: 2019
    Verlag:  HAL CCSD ; Public Library of Science

    International audience ; Background: Zoonotic pathogens respond to changes in host range and/or pathogen, vector and host ecology. Environmental changes (biodiversity, habitat changes, variability in climate), even at a local level, lead to... mehr

     

    International audience ; Background: Zoonotic pathogens respond to changes in host range and/or pathogen, vector and host ecology. Environmental changes (biodiversity, habitat changes, variability in climate), even at a local level, lead to variability in environmental pathogen dynamics and can facilitate their transmission from natural reservoirs to new susceptible hosts. Whilst the environmental dynamics of aquatic bacteria are directly linked to seasonal changes of their habitat they also rely on the ecological processes underpining their transmission. However data allowing the comparison of these ecological processes are lacking. Here we compared the environmental dynamics of generalist and vector-borne aquatic bacterial pathogens in the same unit of time and space, and across rural and urban habitats in French Guiana (South America).Principal findings: Using Leptospira sp. and Mycobacterium ulcerans we performed an environmental survey that allowed the detection of both pathogens in urban vs. rural areas, and during rainy vs. dry weather conditions. All samples were subjected to qPCR amplifications of LipL32 (Leptospira sp.) and IS2404 and KR (M. ulcerans) genetic markers. We found (i) a greater presence of M. ulcerans in rural areas compared with Leptospira sp., (ii) that modified urban environments were more favourable to the establishment of both pathogens, (iii) that Leptospira sp. presence was enhanced during the rainy season and M. ulcerans during the dry period, and (iv) differences in the spatial distribution of both bacteria across urban sites, probably due to the mode of dissemination of each pathogen in the environment.Conclusions: We propose that in French Guiana simplified and modified urban ecosystems might favour leptospirosis and Buruli ulcer emergence and transmission. Moreover, disease risk was also constrained by seasonality. We suggest that the prevention of aquatic bacterial disease emergence in impoverished urban areas of developing countries would benefit from seasonal diseases ...

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Übergeordneter Titel: ISSN: 1935-2727 ; EISSN: 1935-2735 ; PLoS Neglected Tropical Diseases ; https://hal.umontpellier.fr/hal-02063496 ; PLoS Neglected Tropical Diseases, 2019, 13 (1), pp.e0007074. ⟨10.1371/journal.pntd.0007074⟩
    Schlagworte: [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie; [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology; [SDV.EE.SANT]Life Sciences [q-bio]/Ecology; environment/Health; [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases
    Lizenz:

    info:eu-repo/semantics/OpenAccess
  7. Field evaluation of seasonal trends in relative population sizes and dispersal pattern of Aedes albopictus males in support of the design of a sterile male release strategy
    Autor*in: Le Goff, Gilbert; Damiens, David; Ruttee, Abdoul-Hamid; Payet, Laurent; Lebon, Cyrille; Dehecq, Jean-Sébastien; Gouagna, Louis-Clément
    Erschienen: 2019
    Verlag:  HAL CCSD ; BioMed Central

    International audience ; Background: To develop an efficient sterile insect technique (SIT) programme, the number of sterile males to release, along with the spatial and temporal pattern of their release, has to be determined. Such parameters could... mehr

     

    International audience ; Background: To develop an efficient sterile insect technique (SIT) programme, the number of sterile males to release, along with the spatial and temporal pattern of their release, has to be determined. Such parameters could be estimated from a reliable estimation of the wild population density (and its temporal variation) in the area to treat. Here, a series of mark-release-recapture experiments using laboratory-reared and field-derived Aedes albopictus males were carried out in Duparc, a selected pilot site for the future application of SIT in the north of La Reunion Island.Methods: The dispersal, longevity of marked males and seasonal fluctuations in the population size of native mosquitoes were determined from the ratio of marked to unmarked males caught in mice-baited BG-Sentinel traps. The study was conducted during periods of declining population abundance (April), lowest abundance (September) and highest abundance (December).Results: According to data collected in the first 4 days post-release, the Lincoln index estimated population size as quite variable, ranging from 5817 in April, to 639 in September and 5915 in December. Calculations of daily survival probability to 4 days after release for field and laboratory males were 0.91 and 0.98 in April, respectively, and 0.88 and 0.84 in September, respectively. The mean distance travelled (MDT) of released field males were 46 m, 67 m and 37 m for December, April and September experiments, respectively. For released laboratory males, the MDT was 65 m and 42 m in April and September, respectively.Conclusions: Theoretically, the most efficient release programme should be started in July/August when the mosquito population size is the lowest (c.600 wild males/ha relative to 5000 wild males estimated for December and April), with a weekly release of 6000 males/ha. The limited dispersal of Ae. albopictus males highlights the nessecity for the widespread release of sterile males over multiple sites and in a field setting to avoid ...

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Übergeordneter Titel: ISSN: 1756-3305 ; EISSN: 1756-3305 ; Parasites & Vectors ; https://hal.umontpellier.fr/hal-02063510 ; Parasites & Vectors, 2019, 12, pp.81. ⟨10.1186/s13071-019-3329-7⟩
    Schlagworte: Male mosquito; Sterile insect technique (SIT); Mark-release-recapture; [SDE.BE]Environmental Sciences/Biodiversity and Ecology; [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology
    Lizenz:

    info:eu-repo/semantics/OpenAccess
  8. Genome-wide profiling of human papillomavirus DNA integration in liquid-based cytology specimens from a Gabonese female population using HPV capture technology
    Autor*in: Nkili-Meyong, Andriniaina,; Moussavou-Boundzanga, Pamela; Labouba, Ingrid; Koumakpayi, Ismaël,; Jeannot, Emmanuelle; Descorps-Declere, Stéphane; Sastre-Garau, Xavier; M'Baïri, Djébé; Belembaogo, Ernest; Berthet, Nicolas
    Erschienen: 2019
    Verlag:  HAL CCSD ; Nature Publishing Group

    International audience ; Human papillomavirus (HPV) is recognised as the cause of precancerous and cancerous cervical lesions. Furthermore, in high-grade lesions, HPV is frequently integrated in the host cell genome and associated with the partial or... mehr

     

    International audience ; Human papillomavirus (HPV) is recognised as the cause of precancerous and cancerous cervical lesions. Furthermore, in high-grade lesions, HPV is frequently integrated in the host cell genome and associated with the partial or complete loss of the E1 and E2 genes, which regulate the activity of viral oncoproteins E6 and E7. In this study, using a double-capture system followed by high-throughput sequencing, we determined the HPV integration status present in liquid-based cervical smears in an urban Gabonese population. The main inclusion criteria were based on cytological grade and the detection of the HPV16 genotype using molecular assays. The rate of HPV integration in the host genome varied with cytological grade: 85.7% (6/7), 71.4% (5/7), 66.7% (2/3) 60% (3/5) and 30.8% (4/13) for carcinomas, HSIL, ASCH, LSIL and ASCUS, respectively. For high cytological grades (carcinomas and HSIL), genotypes HPV16 and 18 represented 92.9% of the samples (13/14). The integrated form of HPV16 genotype was mainly found in high-grade lesions in 71.4% of samples regardless of cytological grade. Minority genotypes (HPV33, 51, 58 and 59) were found in LSIL samples, except HPV59, which was identified in one HSIL sample. Among all the HPV genotypes identified after double capture, 10 genotypes (HPV30, 35, 39, 44, 45, 53, 56, 59, 74 and 82) were detected only in episomal form. Our study revealed that the degree of HPV integration varies with cervical cytological grade. The integration event might be a potential clinical prognostic biomarker for the prediction of the progression of neoplastic lesions.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Übergeordneter Titel: ISSN: 2045-2322 ; EISSN: 2045-2322 ; Scientific Reports ; https://hal.umontpellier.fr/hal-02063523 ; Scientific Reports, 2019, 9, pp.1504. ⟨10.1038/s41598-018-37871-2⟩
    Schlagworte: [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology
    Lizenz:

    info:eu-repo/semantics/OpenAccess
  9. Implications of insecticide resistance for malaria vector control with long-lasting insecticidal nets: evidence from health facility data from Benin
    Autor*in: Tokponnon, Filémon,; Sissinto, Yolande; Ogouyémi, Aurore,; Adéothy, Adicath,; Adechoubou, Alioun; Houansou, Télesphore; Oke, Mariam; Kindé-Gazard, Dorothée; Massougbodji, Achille; Akogbeto, Martin; Cornelie, Sylvie; Corbel, Vincent; Knox, Tessa,; Mnzava, Abraham,; Donnelly, Martin,; Kleinschmidt, Immo; Bradley, John
    Erschienen: 2019
    Verlag:  HAL CCSD ; BioMed Central

    International audience ; Background: Insecticide-based interventions have averted more than 500 million malaria cases since 2000, but insecticide resistance in mosquitoes could bring about a rebound in disease and mortality. This study investigated... mehr

     

    International audience ; Background: Insecticide-based interventions have averted more than 500 million malaria cases since 2000, but insecticide resistance in mosquitoes could bring about a rebound in disease and mortality. This study investigated whether insecticide resistance was associated with increased incidence of clinical malaria.Methods: In an area of southern Benin with insecticide resistance and high use of insecticide-treated nets (ITNs), malaria morbidity and insecticide resistance were measured simultaneously in 30 clusters (villages or collections of villages) multiple times over the course of 2 years. Insecticide resistance frequencies were measured using the standard World Health Organization bioassay test. Malaria morbidity was measured by cases recorded at health facilities both in the whole population using routinely collected data and in a passively followed cohort of children under 5 years old.Results: There was no evidence that incidence of malaria from routinely collected data was higher in clusters with resistance frequencies above the median, either in children aged under 5 (RR = 1.27 (95% CI 0.81-2.00) p = 0.276) or in individuals aged 5 or over (RR = 1.74 (95% CI 0.91-3.34) p = 0.093). There was also no evidence that incidence was higher in clusters with resistance frequencies above the median in the passively followed cohort (RR = 1.11 (0.52-2.35) p = 0.777).Conclusions: This study found no association between frequency of resistance and incidence of clinical malaria in an area where ITNs are the principal form of vector control. This may be because, as other studies have shown, ITNs continue to offer some protection from malaria even in the presence of insecticide resistance. Irrespective of resistance , nets provide only partial protection so the development of improved or supplementary vector control tools is required to reduce Africa's unacceptably high malaria burden.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Übergeordneter Titel: ISSN: 1475-2875 ; Malaria Journal ; https://hal.umontpellier.fr/hal-02063564 ; Malaria Journal, 2019, 18, pp.37. ⟨10.1186/s12936-019-2656-7⟩
    Schlagworte: Malaria; Insecticide; Resistance; Pyrethroid; Vector; [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie; [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases
    Lizenz:

    info:eu-repo/semantics/OpenAccess
  10. Detection of novel astroviruses among rodents of Gabon, Central Africa
    Autor*in: Mombo, Illich Manfred; Suquet, Eloïse; Boundenga, Larson; Mveang-Nzoghe, Amandine; Maganga-Mboga, Claude; Arnathau, Céline; Sidobre, Christine; M'Baïri, Djébé; Rougeron, Virginie
    Erschienen: 2019
    Verlag:  HAL CCSD ; Elsevier

    International audience mehr

     

    International audience

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Übergeordneter Titel: ISSN: 1567-1348 ; EISSN: 1567-7257 ; Infection, Genetics and Evolution ; https://hal.umontpellier.fr/hal-02063571 ; Infection, Genetics and Evolution, 2019, 68, pp.43-46. ⟨10.1016/j.meegid.2018.12.003⟩
    Schlagworte: [SDV.BID]Life Sciences [q-bio]/Biodiversity
  11. Surveillance in the field: Over-identification of Ebola suspect cases and its contributing factors in West African at-risk contexts
    Autor*in: Desclaux, Alice; Malan, Magne,; Egrot, Marc; Sow, Koudhia; Akindès, Francis
    Erschienen: 2018
    Verlag:  HAL CCSD ; Taylor & Francis (Routledge)

    International audience mehr

     

    International audience

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Übergeordneter Titel: ISSN: 1744-1692 ; EISSN: 1744-1706 ; Global Public Health ; https://hal.science/hal-02064481 ; Global Public Health, 2018, pp.1-13. ⟨10.1080/17441692.2018.1534255⟩
    Schlagworte: [SHS]Humanities and Social Sciences; [SHS.ANTHRO-SE]Humanities and Social Sciences/Social Anthropology and ethnology
  12. Li-and Na-ion Storage Performance of Natural Graphite via Simple Flotation Process
    Autor*in: Ait Laziz, Noureddine; Abou-Rjeily, John; Darwiche, Ali; Toufaily, Joumana; Outzourhit,, Abdelkader; Ghamouss, Fouad; Sougrati, Moulay Tahar
    Erschienen: 2018
    Verlag:  HAL CCSD ; The Korean Electrochemical Society

    International audience ; Natural graphite is obtained from an abandoned open-cast mine and purified by a simple, eco-friendly and affordable beneficiation process including ball milling and flotation process. Both raw graphite (55 wt %) and its... mehr

     

    International audience ; Natural graphite is obtained from an abandoned open-cast mine and purified by a simple, eco-friendly and affordable beneficiation process including ball milling and flotation process. Both raw graphite (55 wt %) and its concentrate (85 wt %) were electrochemically tested in order to evaluate these materials as anode materials for Li-ion and Na ion batteries. It was found that both raw and purified graphites exhibit good electrochemical activities with respect to lithium and sodium ions through completely different reaction mechanisms. The encouraging results demonstrated in this work suggest that both raw and graphite concentrates after flotation could be used respectively for stationary and embedded applications. This strategy would help in developing local electrical storage systems with a significantly low environmental footprint.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Übergeordneter Titel: ISSN: 2093-8551 ; EISSN: 2288-9221 ; Journal of Electrochemical Science and Technology ; https://hal.science/hal-02065013 ; Journal of Electrochemical Science and Technology, 2018, 9 (4), pp.320-329. ⟨10.5229/JECST.2018.9.4.320⟩
    Schlagworte: Natural graphite; Na-ion batteries; Li-ion batteries; Energy storage; Stationary application; Froth flotation; [CHIM]Chemical Sciences; [CHIM.MATE]Chemical Sciences/Material chemistry
    Lizenz:

    creativecommons.org/licenses/by/ ; info:eu-repo/semantics/OpenAccess
  13. Computing and Explaining Query Answers over Inconsistent DL-Lite Knowledge Bases
    Autor*in: Bienvenu, Meghyn; Bourgaux, Camille; Goasdoué, François
    Erschienen: 2019
    Verlag:  HAL CCSD ; Association for the Advancement of Artificial Intelligence

    International audience ; Several inconsistency-tolerant semantics have been introduced for querying inconsistent description logic knowledge bases. The first contribution of this paper is a practical approach for computing the query answers under... mehr

     

    International audience ; Several inconsistency-tolerant semantics have been introduced for querying inconsistent description logic knowledge bases. The first contribution of this paper is a practical approach for computing the query answers under three well-known such semantics, namely the AR, IAR and brave semantics, in the lightweight description logic DL-Lite R. We show that query answering under the intractable AR semantics can be performed efficiently by using IAR and brave semantics as tractable approximations and encoding the AR entail-ment problem as a propositional satisfiability (SAT) problem. The second issue tackled in this work is explaining why a tuple is a (non-)answer to a query under these semantics. We define explanations for positive and negative answers under the brave, AR and IAR semantics. We then study the computational properties of explanations in DL-Lite R. For each type of explanation, we analyze the data complexity of recognizing (preferred) explanations and deciding if a given assertion is relevant or necessary. We establish tight connections between intractable explanation problems and variants of SAT, enabling us to generate explanations by exploiting solvers for Boolean satisfaction and optimization problems. Finally, we empirically study the efficiency of our query answering and explanation framework using a benchmark we built upon the well-established LUBM benchmark.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Übergeordneter Titel: ISSN: 1076-9757 ; Journal of Artificial Intelligence Research ; https://hal.inria.fr/hal-02066288 ; Journal of Artificial Intelligence Research, 2019, 64, pp.563-644. ⟨10.1613/jair.1.11395⟩
    Schlagworte: [INFO.INFO-AI]Computer Science [cs]/Artificial Intelligence [cs.AI]; [INFO.INFO-DB]Computer Science [cs]/Databases [cs.DB]
    Lizenz:

    info:eu-repo/semantics/OpenAccess
  14. Comparison of Anti-Viral Activity of Frog Skin Anti-Microbial Peptides Temporin-Sha and [K3]SHa to LL-37 and Temporin-Tb against Herpes Simplex Virus Type 1
    Autor*in: Roy, Maëva; Lebeau, Lucie; Chessa, Céline; Damour, Alexia; Ladram, Ali; Oury, Bruno; Boutolleau, David; Bodet, Charles; Lévêque, Nicolas
    Erschienen: 2019
    Verlag:  HAL CCSD ; MDPI

    International audience ; Temporins are anti-microbial peptides synthesized in the skin of frogs of the Ranidae family. The few studies to date that have examined their anti-viral properties have shown that they have potential as anti-viral therapies.... mehr

     

    International audience ; Temporins are anti-microbial peptides synthesized in the skin of frogs of the Ranidae family. The few studies to date that have examined their anti-viral properties have shown that they have potential as anti-viral therapies. In this work, we evaluated the anti-herpes simplex virus type 1 (HSV-1) activity of the temporin-SHa (SHa) and its synthetic analog [K³]SHa. Human cathelicidin LL-37 and temporin-Tb (Tb), previously demonstrated to have anti-HSV-1 properties, were used as positive controls. We observed that SHa and [K³]SHa significantly inhibit HSV-1 replication in human primary keratinocytes when used at micromolar concentrations. This anti-viral activity was equivalent to that of Tb, but lower than that of LL-37. Transcriptomic analyses revealed that SHa did not act through the modulation of the cell innate immune response, but rather, displayed virucidal properties by reducing infectious titer of HSV-1 in suspension. In contrast, pre-incubation of the virus with LL-37 suggests that this peptide does not act directly on the viral particle at non-cytotoxic concentrations tested. The anti-HSV-1 activity of LL-37 appears to be due to the potentiation of cellular anti-viral defenses through the induction of interferon stimulated gene expression in infected primary keratinocytes. This study demonstrated that SHa and [K³]SHa, in addition to their previously reported antibacterial and antiparasitic activities, are direct-acting anti-HSV-1 peptides. Importantly, this study extends the little studied anti-viral attributes of frog temporins and offers perspectives for the development of new anti-HSV-1 therapies.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Übergeordneter Titel: ISSN: 1999-4915 ; Viruses ; https://hal.sorbonne-universite.fr/hal-02066789 ; Viruses, 2019, 11 (1), pp.77. ⟨10.3390/v11010077⟩
    Schlagworte: Tb; temporin; SHa; keratinocyte; cytotoxicity; anti-viral; immunomodulation; [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology; [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology
    Lizenz:

    info:eu-repo/semantics/OpenAccess
  15. Epithelial stratification shapes infection dynamics
    Autor*in: Murall, Carmen Lia; Jackson, Robert; Zehbe, Ingeborg; Boulle, Nathalie; Segondy, Michel; Alizon, Samuel
    Erschienen: 2019
    Verlag:  HAL CCSD ; Public Library of Science

    International audience ; Infections of stratified epithelia contribute to a large group of common diseases, such as dermatological conditions and sexually transmitted diseases. To investigate how epithelial structure affects infection dynamics, we... mehr

     

    International audience ; Infections of stratified epithelia contribute to a large group of common diseases, such as dermatological conditions and sexually transmitted diseases. To investigate how epithelial structure affects infection dynamics, we develop a general ecology-inspired model for stratified epithelia. Our model allows us to simulate infections, explore new hypotheses and estimate parameters that are difficult to measure with tissue cell cultures. We focus on two contrasting pathogens: Chlamydia trachomatis and Human papillomaviruses (HPV). Using cervicovaginal parameter estimates, we find that key infection symptoms can be explained by differential interactions with the layers, while clearance and pathogen burden appear to be bottom-up processes. Cell protective responses to infections (e.g. mucus trapping) generally lowered pathogen load but there were specific effects based on infection strategies. Our modeling approach opens new perspectives for 3D tissue culture experimental systems of infections and, more generally, for developing and testing hypotheses related to infections of stratified epithelia. Author summary Many epithelia are stratified in layers of cells and their infection can result in many pathologies, from rashes to cancer. It is important to understand to what extent the epi-thelial structure determines infection dynamics and outcomes. To aid experimental and clinical studies, we develop a mathematical model that recreates epithelial and infection dynamics. By applying it to a virus, human papillomavirus (HPV), and a bacteria, chla-mydia, we show that considering stratification improves our general understanding of disease patterns. For instance, the duration of infection can be driven by the rate at which the stem cells of the epithelium divide. Having a general model also allows us to investigate and compare hypotheses. This ecological framework can be modified to study specific pathogens or to estimate parameters from data generated in 3D skin cell culture experiments. PLOS ...

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
  16. Mycobacterium chimaera Pulmonary Disease in Cystic Fibrosis Patients, France, 2010–2017
    Autor*in: Larcher, R.; Lounnas, Manon; Dumont, Yann; Michon, Anne-Laure; Bonzon, Lucas; Chiron, Raphaël; Carrière, Christian; Klouche, Kada; Godreuil, Sylvain
    Erschienen: 2019
    Verlag:  HAL CCSD ; Centers for Disease Control and Prevention

    International audience mehr

     

    International audience

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Übergeordneter Titel: ISSN: 1080-6040 ; EISSN: 1080-6059 ; Emerging Infectious Diseases ; https://hal.science/hal-02069924 ; Emerging Infectious Diseases, 2019, 25 (3), pp.611-613. ⟨10.3201/eid2503.181590⟩
    Schlagworte: respiratory infections; tuberculosis and other mycobacteria; France; Mycobacterium avium complex; Mycobacterium chimaera; NTM; bacteria; cystic fibrosis; forced expiratory volume; forced vital capacity; nontuberculosis mycobacteria; pulmonary disease; [SDV]Life Sciences [q-bio]
    Lizenz:

    info:eu-repo/semantics/OpenAccess
  17. Le dispositif français de transition vers l’économie circulaire institutionnalise-t-il un concept ? Une analyse transversale de discours
    Autor*in: Savy, Anne-Claire; N’diaye, Malick; Kessari, M.-E.
    Erschienen: 2019
    Verlag:  HAL CCSD ; ISTE OpenScience

    National audience ; This article, based on the theory of the social construction of reality, aims to understand if the construction of the plan of transition towards the circular economy (dispositif de transition vers l’économie circulaire – DTEC)... mehr

     

    National audience ; This article, based on the theory of the social construction of reality, aims to understand if the construction of the plan of transition towards the circular economy (dispositif de transition vers l’économie circulaire – DTEC) induces, in France, the institutionalization of a concept. The emerging concept of the circular economy (économie circulaire – EC) is situated in the context of debates on taking into account the impact of economic activity on nature (l’impact de l’activité économique sur la nature – IAEN). A corpus of French texts, participating in the DTEC since 2008, is the subject of a transversal contextualized analysis of discourse. The results show a diversified institutional job, in the theorization phase, without a common conceptualization of EC but converging on the need for a regulated territorial waste management policy. The institutionalization process is then discussed with the institutional change model. The interactions between institutional pressures to take the IAEN into account introduce the prospect of societal institutional change. ; Cet article vise à comprendre, avec les travaux issus de la théorie de la construction sociale du réel, si la construction du dispositif de transition vers l’économie circulaire (DTEC) induit, en France, l’institutionnalisation d’un concept. Les émergences du concept d’économie circulaire (EC) sont situées dans leur contexte de débats sur la prise en compte de l’impact de l’activité économique sur la nature (IAEN). Un corpus de textes français, participant au DTEC depuis 2008, fait l’objet d’une analyse de discours contextualisée transversale. Les résultats montrent un travail institutionnel diversifié, en phase de théorisation, sans conceptualisation commune sur l’EC mais convergeant sur la nécessité d’une politique territoriale régulée de gestion des déchets. Le processus d’institutionnalisation est ensuite discuté avec le modèle du changement institutionnel. Les interactions entre pressions institutionnelles de prise en compte de ...

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Französisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Übergeordneter Titel: ISSN: 2399-8571 ; Technologie et innovation ; https://hal.umontpellier.fr/hal-02070650 ; Technologie et innovation, 2019, 4 (2), pp.1-25. ⟨10.21494/ISTE.OP.2019.0341⟩
    Schlagworte: SPEECH ANALYSIS; CIRCULAR ECONOMY; INSTITUTIONAL FRAMEWORK; TERRITORY; ADAPTATION TO CHANGE; ENVIRONMENTAL IMPACT; WASTE MANAGEMENT; IMPACT SUR L'ENVIRONNEMENT; GESTION DES DECHETS; ANALYSE DU DISCOURS; ECONOMIE CIRCULAIRE; CADRE INSTITUTIONNEL; CONCEPT; TERRITOIRE; ADAPTATION AU CHANGEMENT; TRANSITION; FRANCE; [SHS.GESTION]Humanities and Social Sciences/Business administration
  18. The impact of thyroid hormone in seasonal breeding has a restricted transcriptional signature
    Autor*in: Lomet, D.; Cognie, Juliette; Chesneau, D.; Dubois, Emeric; Hazlerigg, D.; Dardente, Hugues
    Erschienen: 2018
    Verlag:  HAL CCSD ; Springer Verlag

    Remerciements : Plateforme CIRE, INRA, UMR PRC 0085, Centre Tours Val de Loire ; International audience ; Thyroid hormone (TH) directs seasonal breeding through reciprocal regulation of TH deiodinase (Dio2/Dio3) gene expression in tanycytes in the... mehr

     

    Remerciements : Plateforme CIRE, INRA, UMR PRC 0085, Centre Tours Val de Loire ; International audience ; Thyroid hormone (TH) directs seasonal breeding through reciprocal regulation of TH deiodinase (Dio2/Dio3) gene expression in tanycytes in the ependymal zone of the medio-basal hypothalamus (MBH). Thyrotropin secretion by the pars tuberalis (PT) is a major photoperiod-dependent upstream regulator of Dio2/Dio3 gene expression. Long days enhance thyrotropin production, which increases Dio2 expression and suppresses Dio3 expression, thereby heightening TH signaling in the MBH. Short days appear to exert the converse effect. Here, we combined endocrine profiling and transcriptomics to understand how photoperiod and TH control the ovine reproductive status through effects on hypothalamic function. Almost 3000 genes showed altered hypothalamic expression between the breeding- and non-breeding seasons, showing gene ontology enrichment for cell signaling, epigenetics and neural plasticity. In contrast, acute switching from a short (SP) to a long photoperiod (LP) affected the expression of a much smaller core of 134 LP-responsive genes, including a canonical group previously linked to photoperiodic synchronization. Reproductive switch-off at the end of the winter breeding season was completely blocked by thyroidectomy (THX), despite a very modest effect on the hypothalamic transcriptome. Only 49 genes displayed altered expression between intact and THX ewes, including less than 10% of the LP-induced gene set. Neuroanatomical mapping showed that many LP-induced genes were expressed in the PT, independently of the TH status. In contrast, TH-sensitive seasonal genes were principally expressed in the ependymal zone. These data highlight the distinctions between seasonal remodeling effects, which appear to be largely independent of TH, and TH-dependent localised effects which are permissive for transition to the non-breeding state.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Übergeordneter Titel: ISSN: 1420-682X ; EISSN: 1420-9071 ; Cellular and Molecular Life Sciences ; https://hal.umontpellier.fr/hal-02071096 ; Cellular and Molecular Life Sciences, 2018, 75 (5), pp.905-919. ⟨10.1007/s00018-017-2667-x⟩
    Schlagworte: biological rhythms; circannual clock; GnRH; photoperiod; pituitary; seasonality; sheep; tanycyte; thyrotropin; melatonin; Pars tuberalis; [SDV]Life Sciences [q-bio]
  19. Gaia Data Release 2. Variable stars in the colour-absolute magnitude diagram
    Autor*in: Collaboration, Gaia; Eyer, L.; Rimoldini, L.; Audard, M.; Anderson, R.,; Nienartowicz, K.; Glass, F.; Marchal, O.; Grenon, M.; Mowlavi, N.; Holl, B.; Clementini, G.; Aerts, C.; Mazeh, T.; Evans, D.,; Szabados, L.; Brown, A,; Vallenari, A.; Prusti, T.; de Bruijne, J.; Babusiaux, C.; Biermann, M.; Jansen, F.; Jordi, C.; Klioner, S,; Lammers, U.; Lindegren, L.; Luri, X.; Mignard, F.; Panem, C.; Pourbaix, D.; Randich, S.; Sartoretti, P.; Siddiqui, H.; Soubiran, C.; van Leeuwen, F.; Walton, N.,; Arenou, Frédéric; Bastian, U.; Cropper, M.; Drimmel, R.; Katz, D.; Lattanzi, M.; Bakker, J.; Cacciari, C.; Barache, C.; Barata, C.; Barbato, D.; Barblan, F.; Barklem, P.
    Erschienen: 2019
    Verlag:  HAL CCSD ; EDP Sciences

    International audience ; Context. The ESA Gaia mission provides a unique time-domain survey for more than 1.6 billion sources with G 21 mag. Aims. We showcase stellar variability in the Galactic colour-absolute magnitude diagram (CaMD). We focus on... mehr

     

    International audience ; Context. The ESA Gaia mission provides a unique time-domain survey for more than 1.6 billion sources with G 21 mag. Aims. We showcase stellar variability in the Galactic colour-absolute magnitude diagram (CaMD). We focus on pulsating, eruptive, and cataclysmic variables, as well as on stars that exhibit variability that is due to rotation and eclipses. Methods. We describe the locations of variable star classes, variable object fractions, and typical variability amplitudes throughout the CaMD and show how variability-related changes in colour and brightness induce "motions". To do this, we use 22 months of calibrated photometric, spectro-photometric, and astrometric Gaia data of stars with a significant parallax. To ensure that a large variety of variable star classes populate the CaMD, we crossmatched Gaia sources with known variable stars. We also used the statistics and variability detection modules of the Gaia variability pipeline. Corrections for interstellar extinction are not implemented in this article. Results. Gaia enables the first investigation of Galactic variable star populations in the CaMD on a similar, if not larger, scale as was previously done in the Magellanic Clouds. Although the observed colours are not corrected for reddening, distinct regions are visible in which variable stars occur. We determine variable star fractions to within the current detection thresholds of Gaia. Finally, we report the most complete description of variability-induced motion within the CaMD to date. Conclusions. Gaia enables novel insights into variability phenomena for an unprecedented number of stars, which will benefit the understanding of stellar astrophysics. The CaMD of Galactic variable stars provides crucial information on physical origins of variability in a way that has previously only been accessible for Galactic star clusters or external galaxies. Future Gaia data releases will enable significant improvements over this preview by providing longer time series, more accurate ...

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Übergeordneter Titel: ISSN: 0004-6361 ; EISSN: 1432-0756 ; Astronomy and Astrophysics - A&A ; https://hal.science/hal-02071443 ; Astronomy and Astrophysics - A&A, 2019, 623, pp.A110. ⟨10.1051/0004-6361/201833304⟩
    Schlagworte: [SDU.ASTR.GA]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Galactic Astrophysics [astro-ph.GA]; [SDU.ASTR.SR]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Solar and Stellar Astrophysics [astro-ph.SR]; [PHYS]Physics [physics]; [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]
    Lizenz:

    info:eu-repo/semantics/OpenAccess
  20. Selective sulfoxidation reactions with H2O2 catalyzed by Ti-containing SBA-15 materials
    Autor*in: Andrei, Radu Dorin; Cambruzzi, Nathan; Bonne, Magali; Bénédicte, Lebeau; Hulea, Vasile
    Erschienen: 2019
    Verlag:  HAL CCSD ; Springer Verlag

    International audience ; This contribution relates the behavior of Ti-SBA-15 catalysts in the sulfoxidation reaction with hydrogen peroxide under mild conditions (40–70 °C). Ti-SBA-15 samples with 1, 3 and 5 wt% of TiO2 have been prepared by grafting... mehr

     

    International audience ; This contribution relates the behavior of Ti-SBA-15 catalysts in the sulfoxidation reaction with hydrogen peroxide under mild conditions (40–70 °C). Ti-SBA-15 samples with 1, 3 and 5 wt% of TiO2 have been prepared by grafting SBA-15 silica with Ti(OiPr)4 in ethanol followed by calcination. Due to their mesopores, the Ti-containing catalysts accommodated large molecules like methyl-phenyl-sulfide, diphenylsulfide and dibenzothiophene, which were selectively oxidized into their corresponding sulfoxides and sulfones. The turnover frequency was correlated with the amount of the tetrahedral Ti atoms in the catalyst. During the oxidation process performed in batch mode, with acetonitrile or ethanol as solvent, the catalyst topology and texture were preserved, but the nature of the Ti species suffered some changes.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Übergeordneter Titel: ISSN: 1380-2224 ; EISSN: 1573-4854 ; Journal of Porous Materials ; https://hal.science/hal-02073786 ; Journal of Porous Materials, 2019, 26 (2), pp.533-539. ⟨10.1007/s10934-018-0640-1⟩
    Schlagworte: sulfoxidation; heterogeneous catalysis; [CHIM]Chemical Sciences; [CHIM.CATA]Chemical Sciences/Catalysis
  21. Does advertising the green benefits of products contribute to sustainable development goals? A quasi-experimental test of the dilution effect
    Autor*in: Grolleau, Gilles; Mzoughi, Naoufel; Sutan, Angela
    Erschienen: 2019
    Verlag:  HAL CCSD ; Wiley

    International audience ; Using two studies, we examine the dilution effect for green products, by testing whether advertising green benefits decreases their perceived instrumentality and thus harms sustainable development. We use a between‐subject... mehr

     

    International audience ; Using two studies, we examine the dilution effect for green products, by testing whether advertising green benefits decreases their perceived instrumentality and thus harms sustainable development. We use a between‐subject design and ask participants to evaluate the efficacy of a pen (Study 1) and a dish detergent (Study 2) with and without environmental attributes. Our results are inconsistent with the predictions of the dilution model because the perceived instrumentality of both products does not decrease when environmental benefits are added. Our findings are relevant for eco‐labeling given anecdotal evidence suggesting that adding green information can harm the perceived quality of products.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Übergeordneter Titel: ISSN: 0964-4733 ; EISSN: 1099-0836 ; Business Strategy and the Environment ; https://hal.science/hal-02074770 ; Business Strategy and the Environment, 2019, 28 (5), pp.786-793. ⟨10.1002/bse.2280⟩
    Schlagworte: green products; quality; behavioral economics; dilution model; eco-label; environmental information; [SHS.ECO]Humanities and Social Sciences/Economics and Finance; [SHS.GESTION]Humanities and Social Sciences/Business administration
  22. LSST: from Science Drivers to Reference Design and Anticipated Data Products
    Autor*in: Ivezić, Željko; Kahn, Steven M.; Tyson, J.Anthony; Abel, Bob; Acosta, Emily; Allsman, Robyn; Alonso, David; Alsayyad, Yusra; Anderson, Scott F.; Andrew, John; Angel, James Roger P.; Angeli, George Z.; Ansari, Reza; Antilogus, Pierre; Araujo, Constanza; Armstrong, Robert; Arndt, Kirk T.; Astier, Pierre; Aubourg, Éric; Auza, Nicole; Axelrod, Tim S.; Bard, Deborah J.; Barr, Jeff D.; Barrau, Aurelien; Bartlett, James G.; Bauer, Amanda E.; Bauman, Brian J.; Baumont, Sylvain; Bechtol, Ellen; Bechtol, Keith; Becker, Andrew C.; Becla, Jacek; Beldica, Cristina; Bellavia, Steve; Bianco, Federica B.; Biswas, Rahul; Blanc, Guillaume; Blazek, Jonathan; Blandford, Roger D.; Bloom, Josh S.; Bogart, Joanne; Bond, Tim W.; Booth, Michael T.; Borgland, Anders W.; Borne, Kirk; Bosch, James F.; Boutigny, Dominique; Brackett, Craig A.; Bradshaw, Andrew; Brandt, William Nielsen
    Erschienen: 2019
    Verlag:  HAL CCSD ; American Astronomical Society

    International audience ; We describe here the most ambitious survey currently planned in the optical, the Large Synoptic Survey Telescope (LSST). The LSST design is driven by four main science themes: probing dark energy and dark matter, taking an... mehr

     

    International audience ; We describe here the most ambitious survey currently planned in the optical, the Large Synoptic Survey Telescope (LSST). The LSST design is driven by four main science themes: probing dark energy and dark matter, taking an inventory of the solar system, exploring the transient optical sky, and mapping the Milky Way. LSST will be a large, wide-field ground-based system designed to obtain repeated images covering the sky visible from Cerro Pachón in northern Chile. The telescope will have an 8.4 m (6.5 m effective) primary mirror, a 9.6 deg2 field of view, a 3.2-gigapixel camera, and six filters (ugrizy) covering the wavelength range 320–1050 nm. The project is in the construction phase and will begin regular survey operations by 2022. About 90% of the observing time will be devoted to a deep-wide-fast survey mode that will uniformly observe a 18,000 deg2 region about 800 times (summed over all six bands) during the anticipated 10 yr of operations and will yield a co-added map to r ~ 27.5. These data will result in databases including about 32 trillion observations of 20 billion galaxies and a similar number of stars, and they will serve the majority of the primary science programs. The remaining 10% of the observing time will be allocated to special projects such as Very Deep and Very Fast time domain surveys, whose details are currently under discussion. We illustrate how the LSST science drivers led to these choices of system parameters, and we describe the expected data products and their characteristics.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Übergeordneter Titel: ISSN: 0004-637X ; EISSN: 1538-4357 ; The Astrophysical Journal ; https://hal.science/hal-02080729 ; The Astrophysical Journal, 2019, 873 (2), pp.111. ⟨10.3847/1538-4357/ab042c⟩
    Schlagworte: astrometry; cosmology: observations; Galaxy: general; methods: observational; stars: general; surveys; [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]
  23. Multicentre, prospective, double-blind, randomised controlled clinical trial comparing different non-opioid analgesic combinations with morphine for postoperative analgesia: the OCTOPUS study
    Autor*in: Beloeil, H; Albaladejo, A; Sion, A.; Durand, M.; Martinez, V.; Lasocki, S.; Futier, E.; Verzili, D.; Minville, V.; Fessenmeyer, C.; Belbachir, A.; Aubrun, F.; Renault, A.; Bellissant, E.; Bedague, D.; Blanié, A.; Casez, M.; Chanques, Gerald; Chaize, C.; Dessertaine, G.; Ferré, F.; Gaide Chevronnay, L.; Hébrard, A.; Hespel, A.; Jaber, Samir; de Jong, Audrey; Lahjaouzi, A.; Marino, M.; Moury, H.; Neau, A.; Protar, D.; Rhem, D.; Rineau, E.; Robin, S.; Rossignol, E.; Soucemarianadin, M.; Veaceslav, S.
    Erschienen: 2019
    Verlag:  HAL CCSD ; Oxford University Press (OUP)

    International audience ; Background: Head-to-head comparisons of combinations of more than one non-opioid analgesic (NOA) with morphine alone, for postoperative analgesia, are lacking. The objective of this multicentre, randomised, double-blind... mehr

     

    International audience ; Background: Head-to-head comparisons of combinations of more than one non-opioid analgesic (NOA) with morphine alone, for postoperative analgesia, are lacking. The objective of this multicentre, randomised, double-blind controlled trial was to compare the morphine-sparing effects of different combinations of three NOAs-paracetamol (P), nefopam (N), and ketoprofen (K)-for postoperative analgesia. Methods: Patients from 10 hospitals were randomised to one of eight groups: control (C) received saline as placebo, P, N, K, PN, PK, NK, and PNK. Treatments were given intravenously four times a day during the first 48 h after surgery, and morphine patient-controlled analgesia was used as rescue analgesia. The outcome measures were morphine consumption, pain scores, and morphine-related side-effects evaluated 24 and 48 h after surgery. Results: Two hundred and thirty-seven patients undergoing a major surgical procedure were included between July 2013 and November 2016. Despite a failure to reach a calculated sample size, 24 h morphine consumption [median (interquartile range)] was significantly reduced in the PNK group [5 (1-11) mg] compared with either the C group [27 (11-42) mg; P<0.05] or the N group [21 (12-29) mg; P<0.05]. Results were similar 48 h after surgery. Patients experienced less pain in the PNK group compared with the C, N, and P groups. No difference was observed in the incidence of morphine-related side-effects. Conclusions: Combining three NOAs with morphine allows a significant morphine sparing for 48 h after surgery associated with superior analgesia the first 24 h when compared with morphine alone.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Übergeordneter Titel: ISSN: 0007-0912 ; EISSN: 1471-6771 ; British Journal of Anaesthesia ; https://hal.science/hal-02082182 ; British Journal of Anaesthesia, 2019, 122 (6), pp.e98-e106. &#x27E8;10.1016/j.bja.2018.10.058&#x27E9;
    Schlagworte: opioid sparing; ketoprofen; postoperative analgesia; morphine; non-opioid analgesics; nefopam; paracetamol; [SDV]Life Sciences [q-bio]
    Lizenz:

    info:eu-repo/semantics/OpenAccess
  24. Avian malaria alters the dynamics of blood feeding in Culex pipiens mosquitoes
    Autor*in: Cornet, Stéphane; Nicot, Antoine; Rivero, Ana,; Gandon, Sylvain
    Erschienen: 2019
    Verlag:  HAL CCSD ; BioMed Central

    International audience ; Background: Some Plasmodium species have the ability to modify the behaviour of their mosquito vectors. This is thought to be an adaptive strategy that maximizes the parasite's transmission.Methods: The effect of Plasmodium... mehr

     

    International audience ; Background: Some Plasmodium species have the ability to modify the behaviour of their mosquito vectors. This is thought to be an adaptive strategy that maximizes the parasite's transmission.Methods: The effect of Plasmodium relictum infections on the blood feeding behaviour of Culex pipiens quinquefas-ciatus mosquitoes was monitored.Results: Plasmodium infections did not alter the proportion of blood fed mosquitoes but they did affect the dynamics and the size of the blood meal. Sporozoite-infected mosquitoes completed their blood meal 1.3 times later than uninfected mosquitoes and ended up with smaller blood meals.Conclusion: The potential adaptive nature of this manipulation of mosquito behaviour is discussed in the light of previous studies on other malaria models.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Übergeordneter Titel: ISSN: 1475-2875 ; Malaria Journal ; https://hal.umontpellier.fr/hal-02082598 ; Malaria Journal, 2019, 18, pp.82. &#x27E8;10.1186/s12936-019-2690-5&#x27E9;
    Schlagworte: Blood feeding; Culex pipiens; Plasmodium relictum; Malaria; Vector behaviour; [SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoology; [SDV.EE.IEO]Life Sciences [q-bio]/Ecology; environment/Symbiosis; [SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology; [SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]
    Lizenz:

    info:eu-repo/semantics/OpenAccess
  25. Insecticide resistance modifies mosquito response to DEET and natural repellents
    Autor*in: Deletre, Emilie; Martin, Thibaud; Duménil, Claire; Chandre, Fabrice
    Erschienen: 2019
    Verlag:  HAL CCSD ; BioMed Central

    International audience ; Background: Pyrethroid and organophosphate resistance in the malaria vector Anopheles gambiae has led to the search for not only alternative insecticides, but also repellent chemical compounds. However, little is known about... mehr

     

    International audience ; Background: Pyrethroid and organophosphate resistance in the malaria vector Anopheles gambiae has led to the search for not only alternative insecticides, but also repellent chemical compounds. However, little is known about the potential actions of repellents and the cross-resistance risk between insecticide and repellent compounds.Methods: Here we show the action of permethrin, DEET, geraniol, carvacrol, culminaldehyde and cinnamaldehyde against three A. gambiae strains: 'Kis' (Kisumu susceptible strain), 'KdrKis' (pyrethroid resistant strain) and 'AcerKis' (organophosphate resistant strain), the last two differing from the first by a mutation on the kdr and ace1 genes, respectively.Conclusions: Results from the DEET assays show it induced repellency for the resistant KdrKis and AcerKis strains but maintained irritancy for the susceptible strain. More generally, we show resistance genes modify the behavior of An. gambiae, increasing or decreasing the effectiveness of DEET and natural compounds, depending on the mutation. These findings offer a new avenue for research on the target and mechanism of repellent compounds. We discuss these findings in the context of vector control strategies.

     
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Übergeordneter Titel: ISSN: 1756-3305 ; EISSN: 1756-3305 ; Parasites & Vectors ; https://hal.umontpellier.fr/hal-02082610 ; Parasites & Vectors, 2019, 12, pp.89. &#x27E8;10.1186/s13071-019-3343-9&#x27E9;
    Schlagworte: Mortality; Deterrent; Permethrin; Anopheles gambiae; Cinnamaldehyde; Geraniol; [SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoology; [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
    Lizenz:

    info:eu-repo/semantics/OpenAccess