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  1. The World’s Oldest Living Proverb Discovered Thriving in Ethiopia
    Autor*in: Unseth, Peter
    Erschienen: 2019
    Verlag:  Universität Hamburg, Hiob Ludolf Centre for Ethiopian and Eritrean Studies

    The world’s oldest living proverb, from around 3,800 years ago, is found on a tablet from the Assyrian empire. The proverb has been documented from later eras, northwest from the Middle East up into Europe, as far northwestas Britain. Evidence is... mehr

     

    The world’s oldest living proverb, from around 3,800 years ago, is found on a tablet from the Assyrian empire. The proverb has been documented from later eras, northwest from the Middle East up into Europe, as far northwestas Britain. Evidence is given here now demonstrating that the proverb is also found to the south of the Middle East, in Ethiopia. In some places, a cat is substituted for the dog, but the Ethiopian evidence indicates that the dog version of the proverb is original.

     
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    Übergeordneter Titel: Aethiopica; Bd. 21 (2018); 226–236 ; Aethiopica; Vol. 21 (2018); 226–236 ; 2194-4024 ; 1430-1938 ; 10.15460/aethiopica.21.0
    DDC Klassifikation: Sprache (400); Hellenische Literaturen; Klassische griechische Literatur (880)
    Schlagworte: hasty bitch; Alaaba; Guji Oromo; Nuer
    Lizenz:

    Copyright (c) 2019 Peter Unseth
  2. A Fifteenth-Century Ethiopian Homily on the Archangel Uriel
    Autor*in: Tefera, Amsalu
    Erschienen: 2019
    Verlag:  Universität Hamburg, Hiob Ludolf Centre for Ethiopian and Eritrean Studies

    The text presented in this article is the earliest homily in honour of the Archangel Uriel. The homily is attested in two copies: the earlier is EMML 1835 (fols 166ra–181vb) copied during the time of Emperor Zärʾa Yaʿǝqob (r 1434–1468), and the other... mehr

     

    The text presented in this article is the earliest homily in honour of the Archangel Uriel. The homily is attested in two copies: the earlier is EMML 1835 (fols 166ra–181vb) copied during the time of Emperor Zärʾa Yaʿǝqob (r 1434–1468), and the other is EMML 1841 (fols 137vb–151ra) dated to the seventeenth century. The text makes significant use of 4 Ezra and 1 Enoch, depicting Uriel as angelus interpres and helper of Enoch and Ezra.

     
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    Übergeordneter Titel: Aethiopica; Bd. 21 (2018); 87–119 ; Aethiopica; Vol. 21 (2018); 87–119 ; 2194-4024 ; 1430-1938 ; 10.15460/aethiopica.21.0
    DDC Klassifikation: Literatur und Rhetorik (800); Literaturen anderer Sprachen (890); Christentum, Christliche Theologie (230); Handschriften, seltene Bücher (090); Bräuche, Etikette, Folklore (390)
    Schlagworte: angelology; edition; Sabbath; angelological literature; philology
    Lizenz:

    Copyright (c) 2019 Amsalu Tefera Alemu
  3. A Short Apocalyptic Text Based on the Prophecy of Ezra (Esdras Salathiel)
    Autor*in: Haile, Getatchew
    Erschienen: 2019
    Verlag:  Universität Hamburg, Hiob Ludolf Centre for Ethiopian and Eritrean Studies

    The main themes of the text, occasionally ascribed to Ezra (Salathiel), are the Second Coming of Jesus Christ, the end of the world, the future rulers of Ethiopia, and the honouring of the Sabbaths. It is cast in the spirit of 4 Ezra, quoting it and... mehr

     

    The main themes of the text, occasionally ascribed to Ezra (Salathiel), are the Second Coming of Jesus Christ, the end of the world, the future rulers of Ethiopia, and the honouring of the Sabbaths. It is cast in the spirit of 4 Ezra, quoting it and Jubilees occasionally and extensively. As in 4 Ezra, its author is interested in knowing and declaring the future to call the faithful to observe the law and the ordinances. Reckoning the time by cycles, aqmar, provides him the revelation of future events ‘with exact dates’. The text, composed before the sixteenth century, is one more source of Gǝʿǝz apocalyptic literature. The article is an edition and translation of it as preserved in EMML 6429, fols 9v–39r.

     
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    Übergeordneter Titel: Aethiopica; Bd. 21 (2018); 28–86 ; Aethiopica; Vol. 21 (2018); 28–86 ; 2194-4024 ; 1430-1938 ; 10.15460/aethiopica.21.0
    DDC Klassifikation: Literatur und Rhetorik (800); Literaturen anderer Sprachen (890); Christentum, Christliche Theologie (230); Handschriften, seltene Bücher (090); Bibel (220)
    Schlagworte: Bible; edition; eschatology; Sabbath; Zāgwe; philology
    Lizenz:

    Copyright (c) 2019 Getatchew Haile
  4. A New Witness to the Chronicle of John of Nikiu: EMML 7919
    Autor*in: Brown, Jeremy R.; Elagina, Daria
    Erschienen: 2019
    Verlag:  Universität Hamburg, Hiob Ludolf Centre for Ethiopian and Eritrean Studies

    This article introduces a new witness to the Chronicle of John of Nikiu (EMML 7919). It analyses the text of this witness alongside the four previously known Ethiopic manuscripts of this work. The article considers the current state of research on... mehr

     

    This article introduces a new witness to the Chronicle of John of Nikiu (EMML 7919). It analyses the text of this witness alongside the four previously known Ethiopic manuscripts of this work. The article considers the current state of research on the Chronicle of John of Nikiu, including an examination of the textual witnesses, the language of the original composition, and the biographical and historical information of the chronicler. The textual analysis of EMML 7919 demonstrates a strong relation with the text attested in ANL Conti Rossini 27, which suggests that EMML 7919 is highly valuable for the reconstruction of the Ethiopic version of the Chronicle of John of Nikiu. Finally, there is a catalogue entry for EMML 7919, which details the textual and codicological features of the manuscript.

     
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    Übergeordneter Titel: Aethiopica; Bd. 21 (2018); 120–136 ; Aethiopica; Vol. 21 (2018); 120–136 ; 2194-4024 ; 1430-1938 ; 10.15460/aethiopica.21.0
    DDC Klassifikation: Literaturen anderer Sprachen (890); Handschriften, seltene Bücher (090); Geschichte des Altertums bis ca. 499, Archäologie (930); Allgemeine Organisationen, Museumswissenschaft (060); Bibliotheks- und Informationswissenschaften (020)
    Schlagworte: manuscript studies; philology; chronography; catalogue; Egypt
    Lizenz:

    Copyright (c) 2019 Jeremy R. Brown, Daria Elagina
  5. Getatchew Haile, Ethiopian Studies in Honour of Amha Asfaw
    Autor*in: Villa, Massimo
    Erschienen: 2019
    Verlag:  Universität Hamburg, Hiob Ludolf Centre for Ethiopian and Eritrean Studies

    Review mehr

     

    Review

     
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    Übergeordneter Titel: Aethiopica; Bd. 21 (2018); 247–249 ; Aethiopica; Vol. 21 (2018); 247–249 ; 2194-4024 ; 1430-1938 ; 10.15460/aethiopica.21.0
    DDC Klassifikation: Literaturen anderer Sprachen (890); Christentum, Christliche Theologie (230); Handschriften, seltene Bücher (090)
    Schlagworte: Old Amharic; anaphoras; Ethiopian liturgy; Säqoqawä Näfs; Yared; Apocalypse of Baruch; edition; tabot
    Lizenz:

    Copyright (c) 2019 Massimo Villa
  6. Abraham J. Drewes and Jacques Ryckmans, Les inscriptions sudarabes sur bois dans la collection de l’Oosters Instituut conservée dans la bibliothèque universitaire de Leiden
    Autor*in: Bausi, Alessandro
    Erschienen: 2019
    Verlag:  Universität Hamburg, Hiob Ludolf Centre for Ethiopian and Eritrean Studies

    Review mehr

     

    Review

     
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    Übergeordneter Titel: Aethiopica; Bd. 21 (2018); 243–246 ; Aethiopica; Vol. 21 (2018); 243–246 ; 2194-4024 ; 1430-1938 ; 10.15460/aethiopica.21.0
    DDC Klassifikation: Literaturen anderer Sprachen (890); Handschriften, seltene Bücher (090); Andere Sprachen (490); Geschichte des Altertums bis ca. 499, Archäologie (930); Allgemeine Organisationen, Museumswissenschaft (060)
    Schlagworte: epigraphy; inscription; South Arabia
    Lizenz:

    Copyright (c) 2019 Alessandro Bausi
  7. <<A>> connection not made
    the Chapel Point Historic Site Project
    Autor*in: Tennyson, Brian Douglas
    Erschienen: 2003
    Verlag:  The Association for Living History, Farm and Agricultural Museums, North Bloomfield, Ohio

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    Übergeordneter Titel: Enthalten in: Proceedings of the ... Conference and Annual Meeting / ALHFAM - The Association for Living History, Farm and Agricultural Museums; North Bloomfield, Ohio, 2003; 25.2003: Seite 89-93
    Schlagworte: Array
  8. Keys to the Future
    Autor*in: Rentzhog, Sten
    Erschienen: 2007
    Verlag:  The Association for Living History, Farm and Agricultural Museums, North Bloomfield, Ohio

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    Übergeordneter Titel: Enthalten in: Proceedings of the ... Conference and Annual Meeting / ALHFAM - The Association for Living History, Farm and Agricultural Museums; North Bloomfield, Ohio, 2007; 29.2007: Seite 115-121
    Schlagworte: Array
  9. Frederick Beiser: German Idealism. The Struggle against Subjectivism, 1781-1801
    Autor*in: Millán-Zaibert, Elizabeth
    Erschienen: 2004
    Verlag:  Humboldt-Universität zu Berlin

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    Sprache: Englisch
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    DDC Klassifikation: Literatur und Rhetorik (800)
    Schlagworte: Rhetorik; Literaturwissenschaft
  10. Transcendental or Material Oscillation? An Alternative Reading of Friedrich Schlegel's Alternating Principle (Wechselerweis)
    Autor*in: Leventhal, Robert S.
    Erschienen: 2007
    Verlag:  Humboldt-Universität zu Berlin

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    DDC Klassifikation: Literatur und Rhetorik (800)
    Schlagworte: Rhetorik; Literaturwissenschaft
  11. What's Gender Got to do With it?: A Phenomenology of Romantic Love
    Autor*in: Elkholy, Sharin N.
    Erschienen: 1999
    Verlag:  Humboldt-Universität zu Berlin

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    DDC Klassifikation: Literatur und Rhetorik (800)
    Schlagworte: Rhetorik; Literaturwissenschaft
  12. Ralf Klausnitzer: Blaue Blume unterm Hakenkreuz. Die Rezeption der deutschen literarischen Romantik im Dritten Reich
    Autor*in: Millán-Zaibert, Elisabeth
    Erschienen: 2003
    Verlag:  Humboldt-Universität zu Berlin

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    DDC Klassifikation: Literatur und Rhetorik (800)
    Schlagworte: Rhetorik; Literaturwissenschaft
  13. „Und wer bin ich denn?” Wordplay and Identity in Tieck's William Lovell
    Autor*in: Tucker, Brian
    Erschienen: 2004
    Verlag:  Humboldt-Universität zu Berlin

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    DDC Klassifikation: Literatur und Rhetorik (800)
    Schlagworte: Rhetorik; Literaturwissenschaft
  14. Influences of postural alterations on the hemodynamic of the gait in patients with saphenous incompetence. A preliminary study
    Autor*in: Bernardini M.; Quarto G.; Del Sole D.; Bernardini E.
    Erschienen: 2019

    OBJECTIVES: The aim of this study is to verify whether the postural alterations can influence the development of the varicose disease with unilateral and bilateral saphenous incompetence. MATERIALS AND METHODS: 39 patients suffering from saphenous... mehr

    Zitierfähiger Link:
    http://hdl.handle.net/11588/826603

     

    OBJECTIVES: The aim of this study is to verify whether the postural alterations can influence the development of the varicose disease with unilateral and bilateral saphenous incompetence. MATERIALS AND METHODS: 39 patients suffering from saphenous incompetence diagnosed by hemodynamic study with eco-color doppler (20 patients with bilateral venous insufficiency (VI), 19 patients with unilateral VI) have performed the gait analysis though wireless inertial sensor and baropodometry to assess the plantar pressure distribution both statically and dynamically. RESULTS: The 68% and the 60% of subjects suffering from unilateral or bilateral VI present a plantar pressure dysfunction a single foot or both feet in static and/or in dynamic. In 63% of subjects with unilateral VI the propulsion is reduced on the lower limb damaged. The number of asymmetries in walking and dysfunctions in planar pressure in both groups has been calculated. The average number of asymmetries in walking in the group of patients with unilateral VI is significantly greater (p-value=0.0075) compared to the group of patients with bilateral VI. CONCLUSIONS: Plantar pressure and increased valvo-muscular pump pressure (VMPP) are not the main etiological factors that modify the hemodynamic in walking. In unilateral cases the postural alterations may contribute to worsening or to appearance of the varicose veins. Postural disorders treatment in children of phlebopaths during the childhood could maintain the mild condition of varicose disease silent. The treatment in adults suffering from unilateral VI may reduce or prevent the appearance of relapses KEY WORDS: Gait analysis, Hemodynamic of the gait, Postural alterations, Saphenous incompetence, Venous insufficiency.

     
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  15. Next-generation care pathways for allergic rhinitis and asthma multimorbidity: A model for multimorbid non-communicable diseases—Meeting Report (Part 2)
    Autor*in: Bousquet J.; Pham-Thi N.; Bedbrook A.; Agache I.; Annesi-Maesano I.; Ansotegui I.; Anto J. M.; Bachert C.; Benveniste S.; Bewick M.; Billo N.; Bosnic-Anticevich S.; Bosse I.; Brusselle G.; Calderon M. A.; Canonica G. W.; Caraballo L.; Cardona V.; Carriazo A. M.; Cash E.; Cecchi L.; Chu D. K.; Colgan E.; Costa E.; Cruz A. A.; Czarlewski W.; Durham S.; Ebisawa M.; Erhola M.; Fauquert J. -L.; Fokkens W. J.; Fonseca J. A.; Guldemond N.; Iinuma T.; Illario M.; Klimek L.; Kuna P.; Kvedariene V.; Larenas-Linneman D.; Laune D.; Le L. T. T.; Lourenco O.; Malva J. O.; Marien G.; Menditto E.; Mullol J.; Munter L.; Okamoto Y.; Onorato G. L.; Papadopoulos N. G.; Perala M.; Pfaar O.; Phillips A.; Phillips J.; Pinnock H.; Portejoie F.; Quinones-Delgado P.; Rolland C.; Rodts U.; Samolinski B.; Sanchez-Borges M.; Schunemann H. J.; Shamji M.; Somekh D.; Togias A.; Toppila-Salmi S.; Tsiligianni I.; Usmani O.; Walker S.; Wallace D.; Valiulis A.; Van der Kleij R.; Ventura M. T.; Williams S.; Yorgancioglu A.; Zuberbier T.
    Erschienen: 2019

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  16. Next-generation care pathways for allergic rhinitis and asthma multimorbidity: A model for multimorbid non-communicable diseases—Meeting Report (Part 1)
    Autor*in: Bousquet J.; Pham-Thi N.; Bedbrook A.; Agache I.; Annesi-Maesano I.; Ansotegui I.; Anto J. M.; Bachert C.; Benveniste S.; Bewick M.; Billo N.; Bosnic-Anticevich S.; Bosse I.; Brusselle G.; Calderon M. A.; Canonica G. W.; Caraballo L.; Cardona V.; Carriazo A. M.; Cash E.; Cecchi L.; Chu D. K.; Colgan E.; Costa E.; Cruz A. A.; Czarlewski W.; Durham S.; Ebisawa M.; Erhola M.; Fauquert J. -L.; Fokkens W. J.; Fonseca J. A.; Guldemond N.; Iinuma T.; Illario M.; Klimek L.; Kuna P.; Kvedariene V.; Larenas-Linneman D.; Laune D.; Le L. T. T.; Lourenco O.; Malva J. O.; Marien G.; Menditto E.; Mullol J.; Munter L.; Okamoto Y.; Onorato G. L.; Papadopoulos N. G.; Perala M.; Pfaar O.; Phillips A.; Phillips J.; Pinnock H.; Portejoie F.; Quinones-Delgado P.; Rolland C.; Rodts U.; Samolinski B.; Sanchez-Borges M.; Schunemann H. J.; Shamji M.; Somekh D.; Togias A.; Toppila-Salmi S.; Tsiligianni I.; Usmani O.; Walker S.; Wallace D.; Valiulis A.; Van Der Kleij R.; Ventura M. T.; Williams S.; Yorgancioglu A.; Zuberbier T.
    Erschienen: 2019

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  17. Mobile Technology in Allergic Rhinitis: Evolution in Management or Revolution in Health and Care?
    Autor*in: Bousquet J.; Ansotegui I. J.; Anto J. M.; Arnavielhe S.; Bachert C.; Basagana X.; Bedard A.; Bedbrook A.; Bonini M.; Bosnic-Anticevich S.; Braido F.; Cardona V.; Czarlewski W.; Cruz A. A.; Demoly P.; De Vries G.; Dramburg S.; Mathieu-Dupas E.; Erhola M.; Fokkens W. J.; Fonseca J. A.; Haahtela T.; Hellings P. W.; Illario M.; Ivancevich J. C.; Jormanainen V.; Klimek L.; Kuna P.; Kvedariene V.; Laune D.; Larenas-Linnemann D.; Lourenco O.; Onorato G. L.; Matricardi P. M.; Melen E.; Mullol J.; Papadopoulos N. G.; Pfaar O.; Pham-Thi N.; Sheikh A.; Tan R.; To T.; Tomazic P. V.; Toppila-Salmi S.; Tripodi S.; Wallace D.; Valiulis A.; van Eerd M.; Ventura M. T.; Yorgancioglu A.; Zuberbier T.
    Erschienen: 2019

    Smart devices and Internet-based applications (apps) are largely used in allergic rhinitis and may help to address some unmet needs. However, these new tools need to first of all be tested for privacy rules, acceptability, usability, and... mehr

     

    Smart devices and Internet-based applications (apps) are largely used in allergic rhinitis and may help to address some unmet needs. However, these new tools need to first of all be tested for privacy rules, acceptability, usability, and cost-effectiveness. Second, they should be evaluated in the frame of the digital transformation of health, their impact on health care delivery, and health outcomes. This review (1) summarizes some existing mobile health apps for allergic rhinitis and reviews those in which testing has been published, (2) discusses apps that include risk factors of allergic rhinitis, (3) examines the impact of mobile health apps in phenotype discovery, (4) provides real-world evidence for care pathways, and finally (5) discusses mobile health tools enabling the digital transformation of health and care, empowering citizens, and building a healthier society.

     
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    Schlagworte: App; Digital transformation of health; MASK; mHealth; Mobile technology; Rhiniti; Delivery of Health Care; Europe; Human; Mobile Application; Phenotype; Rhinitis; Allergic; Risk Factor; Telemedicine; Smartphone
  18. Percolation transition in a dynamically clustered network
    Autor*in: Zen A.; Kabakcioglu A.; Stella A. L.
    Erschienen: 2007

    We consider a percolationlike phenomenon on a generalization of the Barabási-Albert model, where a modification of the growth dynamics directly allows formation of disconnected clusters. The transition is located with high precision by an original... mehr

     

    We consider a percolationlike phenomenon on a generalization of the Barabási-Albert model, where a modification of the growth dynamics directly allows formation of disconnected clusters. The transition is located with high precision by an original numerical technique based on the comparison of the largest and second largest clusters. A careful investigation focusing on finite size scaling allows us to highlight properties which would hardly be accessible by an analytical solution of cluster growth equations in the stationary limit. Our analysis shows that some critical features of the percolation transition are different from those observed in the case of dilution in fully grown networks. At variance with other models of percolation on growing networks we also find evidence that the order parameter approaches zero as a power of the field p- pc driving the transition, rather than as a stretched exponential. This behavior does not agree with the Berezinskii-Kosterlitz- Thouless scenario found in other similar models. For describing the phase in which a giant cluster develops, a key role is played by the crossover number of nodes Nx ∼ (p- pc) -ζ with ζ 4. This power law behavior and that of other quantities are conjectured on the basis of scaling arguments and numerical evidence. © 2007 The American Physical Society.

     
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  19. Dietary polyphenols and type 2 diabetes: Human Study and Clinical Trial
    Autor*in: Cao H.; Ou J.; Chen L.; Zhang Y.; Szkudelski T.; Delmas D.; Daglia M.; Xiao J.
    Erschienen: 2019

    Significant evidence from epidemiological investigations showed that dietary polyphenols might manage and prevent type 2 diabetes (T2D). This review summarizes human studies and clinical trials of polyphenols as anti-diabetic agents. Polyphenols from... mehr

     

    Significant evidence from epidemiological investigations showed that dietary polyphenols might manage and prevent type 2 diabetes (T2D). This review summarizes human studies and clinical trials of polyphenols as anti-diabetic agents. Polyphenols from coffee, guava tea, whortleberry, olive oil, propolis, chocolate, red wine, grape seed, and cocoa have been reported to show anti-diabetic effects in T2D patients through increasing glucose metabolism, improving vascular function as well as reducing insulin resistance and HbA1c level. However, individual flavonoid or isoflavonoid compounds appear to have no therapeutic effect on diabetes, based on the limited clinical data. Preliminary clinical trials provided evidence that resveratrol had anti-diabetic activity in humans by improving glycemic control in subjects with insulin resistance. Besides, anthocyanins exhibited anti-diabetic properties by reducing blood glucose and HbA1c levels or the improvement of insulin secretion and resistance. The structure-activity relationship of polyphenols as anti-diabetic agents in humans has been rarely reported.

     
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    Schlagworte: clinical trial; Dietary polyphenol; human Study; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Human; Hypoglycemic Agent; Polyphenol; Diet; Insulin Resistance
  20. Shedding light on the migratory patterns of the Amazonian goliath catfish, Brachyplatystoma platynemum , using otolith 87 Sr/ 86 Sr analyses
    Autor*in: Hauser, Marilia; Doria, Carolina R.C.; Santos, Roberto; García-Vasquez, Aurea; Pouilly, Marc; Pécheyran, Christophe; Ponzevera, Emmanuel; Torrente-Vilara, Gislene; Bérail, Sylvain; Panfili, Jacques; Darnaude, Audrey,; Renno, Jean-François; García-Dávila, Carmen; Nuñez, Jesus; Ferraton, Franck; Vargas, Gladys; Duponchelle, Fabrice
    Erschienen: 2019
    Verlag:  HAL CCSD ; Wiley

    International audience ; In the Amazon, migratory catfishes of the genus Brachyplatystoma are apex predators that are important for fisheries and conservation. The life cycle of Brachyplatystoma platynemum Boulenger, 1898 is poorly known, although it... mehr

     

    International audience ; In the Amazon, migratory catfishes of the genus Brachyplatystoma are apex predators that are important for fisheries and conservation. The life cycle of Brachyplatystoma platynemum Boulenger, 1898 is poorly known, although it has been hypothesized to be very similar to that of Brachyplatystoma rousseauxii Castelnau, 1855, which uses the entire length of the Amazon basin to complete its life cycle (from the Andes to the estuary). This study provides the first data on the migratory patterns of B. platynemum at the individual level using otolith microchemistry. In total, 94 individuals were sampled close to major breeding areas in the Amazon basin (78 fish from the middle and upper Madeira River and 14 fish from the upper Amazon), and their lifetime movements were assessed by measuring variations in 87 Sr/ 86 Sr along transverse sections of their otoliths (ear stones), using laser ablation multi-collector mass spectrometry (LA-MC-ICP-MS). The migrations of B. platynemum are not as extensive as those of B. rousseauxii, and do not involve natal homing. Furthermore, the estuary is not a nursery area, at least for fish hatched in the Madeira. Nevertheless, B. platynemum migrates several thousand kilometres within the Amazon basin, with transboundary displacements between at least Bolivia, Brazil, and Peru. Current and planned hydroelectric development in the Amazon basin will severely disrupt both migration and access to breeding grounds, ultimately affecting the recruitment and population dynamics of these apex predators. The conservation of B. platynemum is crucial for the stability of the Amazonian aquatic food webs. This requires building effective fish passage on the two existing Madeira dams and considering alternative options to the large-scale hydropower development in the Amazon basin

     
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    Übergeordneter Titel: ISSN: 1052-7613 ; EISSN: 1099-0755 ; Aquatic Conservation: Marine and Freshwater Ecosystems ; https://hal.science/hal-02055491 ; Aquatic Conservation: Marine and Freshwater Ecosystems, 2019, 29 (3), pp.397-408. &#x27E8;10.1002/aqc.3046&#x27E9;
    Schlagworte: fish; conservation evaluation; catchment; fishing; hydroelectric dams; migration; river; [CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry; [CHIM.ANAL]Chemical Sciences/Analytical chemistry; [CHIM.POLY]Chemical Sciences/Polymers; [CHIM.MATE]Chemical Sciences/Material chemistry
  21. Multicenter Evaluation of a Novel Immunochromatographic Test for Anti-aspergillus IgG Detection
    Autor*in: Piarroux, Raphael P.; Romain, Thomas; Martin, Aurelie; Vainqueur, Damien; Vitte, Joana; Lachaud, Laurence; Gangneux, Jean-Pierre; Gabriel, Frédéric; Fillaux, Judith; Ranque, Stéphane
    Erschienen: 2019
    Verlag:  HAL CCSD ; Frontiers

    International audience ; Aspergillus sp. fungi cause various diseases in both immunocompetent and immunocompromised patients. The most frequent Aspergillus disorders include chronic pulmonary aspergillosis (CPA), a life-threatening disease that... mehr

     

    International audience ; Aspergillus sp. fungi cause various diseases in both immunocompetent and immunocompromised patients. The most frequent Aspergillus disorders include chronic pulmonary aspergillosis (CPA), a life-threatening disease that affects at least 3 million people worldwide, and allergic bronchopulmonary aspergillosis (ABPA), which affects approximately 4.8 million severe asthmatic patients globally. Diagnosis of such diseases involves IgG serological testing; however, the currently available anti-Aspergillus IgG detection assays are inappropriate for resource-poor laboratory settings, as they are expensive, rely on automated procedures, and require stable electrical power. Therefore, accurate CPA or ABPA diagnosis facilities are lacking in most low- and middle-income countries. We evaluated a novel anti-Aspergillus antibody immunochromatographic test (ICT) that requires minimal laboratory equipment. Two evaluations were performed a single-center 4-month prospective study in a French reference laboratory (44 cases/257 patients) and a retrospective study in five French reference laboratories (262 cases and 188 controls). We estimated the ICT indices for the diagnosis of chronic aspergillosis, and the test results were compared to those of anti-Aspergillus IgG immunoblot (IB) assay. Of the 713 patients included in the study, 306 had chronic aspergillosis. Test sensitivity and specificity were 88.9%(95% CI[85-92]) and 96.3%(95% CI[94-98]) for the ICT and 93.1% (95% CI[90-96]) and 94.3% (95% CI[92-96]) for the IB, respectively. Agreement between the two assays was almost perfect (kappa = 0.86). As this ICT displays good diagnostic performance and complies with the ASSURED (Affordable, Sensitive, Specific, User-friendly, Equipment-free, and Delivered) criteria, we concluded that this anti-Aspergillus antibody ICT can be used to diagnose Aspergillus diseases in resource-poor settings.

     
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    Übergeordneter Titel: ISSN: 2235-2988 ; Frontiers in Cellular and Infection Microbiology ; https://hal-univ-rennes1.archives-ouvertes.fr/hal-02061628 ; Frontiers in Cellular and Infection Microbiology, 2019, 9, pp.12. &#x27E8;10.3389/fcimb.2019.00012&#x27E9;
    Schlagworte: immunochromatography; allergic broncho-pulmonary aspergillosis; sensitivity; Aspergillus serology; point-of-care; chronic pulmonary aspergillosis; specificity; [SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/Mycology; [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases
    Lizenz:

    creativecommons.org/licenses/by/ ; info:eu-repo/semantics/OpenAccess
  22. Cranial nerve involvement in patients with MOG antibody–associated disease
    Autor*in: Cobo-Calvo, Alvaro; Ayrignac, Xavier; Kerschen, Philippe; Horellou, Philippe; Cotton, François; Labauge, Pierre; Vukusic, Sandra; Deiva, Kumaran; Serguera, Che; Marignier, Romain
    Erschienen: 2019
    Verlag:  HAL CCSD

    International audience mehr

     

    International audience

     
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    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Übergeordneter Titel: Neurology - Neuroimmunology Neuroinflammation ; https://hal.science/hal-02063145 ; Neurology - Neuroimmunology Neuroinflammation, 2019, 6 (2), pp.e543. &#x27E8;10.1212/NXI.0000000000000543&#x27E9;
    Schlagworte: [SDV]Life Sciences [q-bio]
  23. Comparison of Mycobacterium ulcerans (Buruli ulcer) and Leptospira sp. (Leptospirosis) dynamics in urban and rural settings
    Autor*in: Combe, Marine; Gozlan, Rodolphe Elie; Jagadesh, Soushieta; Velvin, Camilla Jensen; Ruffine, Rolland; Demar, Magalie Pierre; Couppié, Pierre; Djossou, Félix; Nacher, Mathieu; Epelboin, Loïc
    Erschienen: 2019
    Verlag:  HAL CCSD ; Public Library of Science

    International audience ; Background: Zoonotic pathogens respond to changes in host range and/or pathogen, vector and host ecology. Environmental changes (biodiversity, habitat changes, variability in climate), even at a local level, lead to... mehr

     

    International audience ; Background: Zoonotic pathogens respond to changes in host range and/or pathogen, vector and host ecology. Environmental changes (biodiversity, habitat changes, variability in climate), even at a local level, lead to variability in environmental pathogen dynamics and can facilitate their transmission from natural reservoirs to new susceptible hosts. Whilst the environmental dynamics of aquatic bacteria are directly linked to seasonal changes of their habitat they also rely on the ecological processes underpining their transmission. However data allowing the comparison of these ecological processes are lacking. Here we compared the environmental dynamics of generalist and vector-borne aquatic bacterial pathogens in the same unit of time and space, and across rural and urban habitats in French Guiana (South America).Principal findings: Using Leptospira sp. and Mycobacterium ulcerans we performed an environmental survey that allowed the detection of both pathogens in urban vs. rural areas, and during rainy vs. dry weather conditions. All samples were subjected to qPCR amplifications of LipL32 (Leptospira sp.) and IS2404 and KR (M. ulcerans) genetic markers. We found (i) a greater presence of M. ulcerans in rural areas compared with Leptospira sp., (ii) that modified urban environments were more favourable to the establishment of both pathogens, (iii) that Leptospira sp. presence was enhanced during the rainy season and M. ulcerans during the dry period, and (iv) differences in the spatial distribution of both bacteria across urban sites, probably due to the mode of dissemination of each pathogen in the environment.Conclusions: We propose that in French Guiana simplified and modified urban ecosystems might favour leptospirosis and Buruli ulcer emergence and transmission. Moreover, disease risk was also constrained by seasonality. We suggest that the prevention of aquatic bacterial disease emergence in impoverished urban areas of developing countries would benefit from seasonal diseases ...

     
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    Übergeordneter Titel: ISSN: 1935-2727 ; EISSN: 1935-2735 ; PLoS Neglected Tropical Diseases ; https://hal.umontpellier.fr/hal-02063496 ; PLoS Neglected Tropical Diseases, 2019, 13 (1), pp.e0007074. &#x27E8;10.1371/journal.pntd.0007074&#x27E9;
    Schlagworte: [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie; [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology; [SDV.EE.SANT]Life Sciences [q-bio]/Ecology; environment/Health; [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases
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    info:eu-repo/semantics/OpenAccess
  24. Field evaluation of seasonal trends in relative population sizes and dispersal pattern of Aedes albopictus males in support of the design of a sterile male release strategy
    Autor*in: Le Goff, Gilbert; Damiens, David; Ruttee, Abdoul-Hamid; Payet, Laurent; Lebon, Cyrille; Dehecq, Jean-Sébastien; Gouagna, Louis-Clément
    Erschienen: 2019
    Verlag:  HAL CCSD ; BioMed Central

    International audience ; Background: To develop an efficient sterile insect technique (SIT) programme, the number of sterile males to release, along with the spatial and temporal pattern of their release, has to be determined. Such parameters could... mehr

     

    International audience ; Background: To develop an efficient sterile insect technique (SIT) programme, the number of sterile males to release, along with the spatial and temporal pattern of their release, has to be determined. Such parameters could be estimated from a reliable estimation of the wild population density (and its temporal variation) in the area to treat. Here, a series of mark-release-recapture experiments using laboratory-reared and field-derived Aedes albopictus males were carried out in Duparc, a selected pilot site for the future application of SIT in the north of La Reunion Island.Methods: The dispersal, longevity of marked males and seasonal fluctuations in the population size of native mosquitoes were determined from the ratio of marked to unmarked males caught in mice-baited BG-Sentinel traps. The study was conducted during periods of declining population abundance (April), lowest abundance (September) and highest abundance (December).Results: According to data collected in the first 4 days post-release, the Lincoln index estimated population size as quite variable, ranging from 5817 in April, to 639 in September and 5915 in December. Calculations of daily survival probability to 4 days after release for field and laboratory males were 0.91 and 0.98 in April, respectively, and 0.88 and 0.84 in September, respectively. The mean distance travelled (MDT) of released field males were 46 m, 67 m and 37 m for December, April and September experiments, respectively. For released laboratory males, the MDT was 65 m and 42 m in April and September, respectively.Conclusions: Theoretically, the most efficient release programme should be started in July/August when the mosquito population size is the lowest (c.600 wild males/ha relative to 5000 wild males estimated for December and April), with a weekly release of 6000 males/ha. The limited dispersal of Ae. albopictus males highlights the nessecity for the widespread release of sterile males over multiple sites and in a field setting to avoid ...

     
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    Übergeordneter Titel: ISSN: 1756-3305 ; EISSN: 1756-3305 ; Parasites & Vectors ; https://hal.umontpellier.fr/hal-02063510 ; Parasites & Vectors, 2019, 12, pp.81. &#x27E8;10.1186/s13071-019-3329-7&#x27E9;
    Schlagworte: Male mosquito; Sterile insect technique (SIT); Mark-release-recapture; [SDE.BE]Environmental Sciences/Biodiversity and Ecology; [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology
    Lizenz:

    info:eu-repo/semantics/OpenAccess
  25. Genome-wide profiling of human papillomavirus DNA integration in liquid-based cytology specimens from a Gabonese female population using HPV capture technology
    Autor*in: Nkili-Meyong, Andriniaina,; Moussavou-Boundzanga, Pamela; Labouba, Ingrid; Koumakpayi, Ismaël,; Jeannot, Emmanuelle; Descorps-Declere, Stéphane; Sastre-Garau, Xavier; M'Baïri, Djébé; Belembaogo, Ernest; Berthet, Nicolas
    Erschienen: 2019
    Verlag:  HAL CCSD ; Nature Publishing Group

    International audience ; Human papillomavirus (HPV) is recognised as the cause of precancerous and cancerous cervical lesions. Furthermore, in high-grade lesions, HPV is frequently integrated in the host cell genome and associated with the partial or... mehr

     

    International audience ; Human papillomavirus (HPV) is recognised as the cause of precancerous and cancerous cervical lesions. Furthermore, in high-grade lesions, HPV is frequently integrated in the host cell genome and associated with the partial or complete loss of the E1 and E2 genes, which regulate the activity of viral oncoproteins E6 and E7. In this study, using a double-capture system followed by high-throughput sequencing, we determined the HPV integration status present in liquid-based cervical smears in an urban Gabonese population. The main inclusion criteria were based on cytological grade and the detection of the HPV16 genotype using molecular assays. The rate of HPV integration in the host genome varied with cytological grade: 85.7% (6/7), 71.4% (5/7), 66.7% (2/3) 60% (3/5) and 30.8% (4/13) for carcinomas, HSIL, ASCH, LSIL and ASCUS, respectively. For high cytological grades (carcinomas and HSIL), genotypes HPV16 and 18 represented 92.9% of the samples (13/14). The integrated form of HPV16 genotype was mainly found in high-grade lesions in 71.4% of samples regardless of cytological grade. Minority genotypes (HPV33, 51, 58 and 59) were found in LSIL samples, except HPV59, which was identified in one HSIL sample. Among all the HPV genotypes identified after double capture, 10 genotypes (HPV30, 35, 39, 44, 45, 53, 56, 59, 74 and 82) were detected only in episomal form. Our study revealed that the degree of HPV integration varies with cervical cytological grade. The integration event might be a potential clinical prognostic biomarker for the prediction of the progression of neoplastic lesions.

     
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    Übergeordneter Titel: ISSN: 2045-2322 ; EISSN: 2045-2322 ; Scientific Reports ; https://hal.umontpellier.fr/hal-02063523 ; Scientific Reports, 2019, 9, pp.1504. &#x27E8;10.1038/s41598-018-37871-2&#x27E9;
    Schlagworte: [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology
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    info:eu-repo/semantics/OpenAccess