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  1. Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing
    Erschienen: 2012
    Verlag:  Springer-Verlag Berlin Heidelberg, Berlin, Heidelberg

    The objective of this CTMI volume is to provide readers with a foundation for understanding what ADARs are and how they act to affect gene expression and function. Because A-to-I editing may affect base-pairing and RNA structure, processes including... mehr

    Universität Potsdam, Universitätsbibliothek
    uneingeschränkte Fernleihe, Kopie und Ausleihe

     

    The objective of this CTMI volume is to provide readers with a foundation for understanding what ADARs are and how they act to affect gene expression and function. Because A-to-I editing may affect base-pairing and RNA structure, processes including translation, splicing, RNA replication, and miR and siRNA silencing may be affected.¡ It also is becoming increasingly apparent that ADARs may possess roles not only as enzymes that deaminate adenosine to produce inosine in RNA substrates with double-stranded character, but also as proteins independent of their catalytic property. Future studies of ADARs no doubt will provide us with additional surprises and new insights into the modulation of biological processes by the ADAR family of proteins The objective of this "CTMI" volume is to provide readers with a foundation for understanding what ADARs are and how they act to affect gene expression and function. It is becoming increasingly apparent that ADARs may possess roles not only as enzymes that deaminate adenosine to produce inosine in RNA substrates with double-stranded character, but also as proteins independent of their catalytic property. Because A-to-I editing may affect base-pairing and RNA structure, processes including translation, splicing, RNA replication, and miR and siRNA silencing may be affected. Future stud

     

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    Hinweise zum Inhalt
    Volltext (lizenzpflichtig)
    Quelle: Verbundkataloge
    Sprache: Englisch
    Medientyp: Ebook
    Format: Online
    ISBN: 9783642228018
    Weitere Identifier:
    RVK Klassifikation: WD 5065
    Schriftenreihe: Current Topics in Microbiology and Immunology ; 353
    Schlagworte: Medicine; Human physiology; Adenosine Deaminase; RNA Editing; RNA, Double-Stranded
    Umfang: Online-Ressource, v.: digital
    Bemerkung(en):

    Description based upon print version of record

    Electronic reproduction; Available via World Wide Web

    Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing; Preface; Contents; Contributors; 144 ADAR Proteins: Structure and Catalytic Mechanism; Abstract; 1…The Reaction Catalyzed by ADARs; 2…The ADAR Protein Structure is Modular; 3…Overview of Structure of ADAR2 Deaminase Domain; 4…H394, C451, C516: Zn2+ Binding; 4.1 E396; 4.2 T375; 4.3 R455; 5…Residues Involved in IP6 Binding; 6…Roles of Functional Groups in RNA Substrate at or Near the Deamination Site; 7…The Effect of Helix Defects; 8…Preferred Flanking Sequence; 9…A--C Mismatch at Editing Site

    10…2vprime-Hydroxyl of the Edited Nucleoside11…8-Aza Substitution at Edited Adenosine; 12…N7 of Substrate, C7 Substituents on Adenosine Analogs; 13…C6- and C2-Positions of the Edited Purine; 13.1 The ADAR Reaction Mechanism; 13.2 Dimerization; 13.3 Substrate Binding and Conformational Changes; 13.4 Deamination in the ADAR Active Site and Product Release; Acknowledgments; References; 145 ADAR Proteins: Double-stranded RNA and Z-DNA Binding Domains; Abstract; 1…Introduction; 2…Adenosine Deaminases Acting on RNA Family Members and Their Domain Organization; 3…RNA Editing Substrate

    3.1 Specificity of Editing3.2 What Makes a Good Editing Site?; 3.2.1 Preferences; 3.2.2 Selectivity; 3.3 Structures of Editing Substrates; 4…Adenosine Deaminases Acting on RNA Z-DNA Binding Domains; 4.1 Z-DNA Binding Domain: Structure and Substrate Recognition; 4.2 A Role for ADAR1 Z alpha Domain?; 4.3 How Does a Z-DNA Binding Domain Bind to Z-DNA?; 4.4 ADAR1 Z beta Domain: a Domain for Protein--Protein Interaction?; 5…Adenosine Deaminases Acting on RNA dsRNA Binding Domains; 5.1 Structural Characteristics of a dsRNA Binding Domain; 5.2 Sequence Specific Recognition with dsRBD

    5.3 How dsRBDs are Positioned on Substrate?5.4 Are the Binding Sites of ADAR dsRBDs Predictable?; 6…dsRBDs and Z-DNA Binding Domains Act on the Subcellular Localization of ADARs; 7…Concluding Remarks; Acknowledgments; References; 157 Editing of Neurotransmitter Receptor and Ion Channel RNAs in the Nervous System; Abstract; 1…Introduction; 2…Identification of A-to-I Editing Targets; 3…Mammalian ADAR Enzymes; 4…ADAR Substrates in the Central Nervous System; 4.1 Glutamate-Gated Ion Channels; 4.1.1 AMPA Receptors; 4.1.2 Kainate Receptors; 4.2 The Serotonin 2C Receptor (5HT2C)

    4.3 The alpha 3 Subunit of the GABAA Receptor (Gabra3)4.4 Voltage-gated Potassium Channel (Kv1.1); 5…Conclusions; References; 151 Modulation of MicroRNA Expression and Function by ADARs; Abstract; 1…Introduction; 2…MiRNA Biogenesis and Function; 3…Editing of MiRNAs; 3.1 Identification of Pri-MiRNA Editing Sites; 3.1.1 Systematic Surveys for MiRNA Editing Sites; 3.1.2 High-Throughput Sequencing of Mature MiRNAs; 3.2 Consequences of Pri-MiRNA Editing; 3.2.1 Effect on Drosha Cleavage; 3.2.2 Degradation of Inosine-Containing Pri-MiRNAs; 3.2.3 Effect on Dicer Cleavage; 3.2.4 Effect on RISC Loading

    3.2.5 Effect on Mature MiRNA Function

  2. Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing
    Erschienen: 2012
    Verlag:  Springer-Verlag Berlin Heidelberg, Berlin, Heidelberg

    Hochschule Rhein-Waal, Zweigbibliothek Kamp-Lintfort
    uneingeschränkte Fernleihe, Kopie und Ausleihe
    Hochschule Rhein-Waal, Bibliothek
    uneingeschränkte Fernleihe, Kopie und Ausleihe
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: Verbundkataloge
    Sprache: Englisch
    Medientyp: Ebook
    Format: Online
    ISBN: 9783642228018
    Weitere Identifier:
    Schriftenreihe: Current Topics in Microbiology and Immunology ; 353
    Schlagworte: Medicine; Human physiology; RNS-Edierung; Adenosindesaminase
  3. Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing
    Erschienen: 2012
    Verlag:  Springer-Verlag Berlin Heidelberg, Berlin, Heidelberg

    The objective of this CTMI volume is to provide readers with a foundation for understanding what ADARs are and how they act to affect gene expression and function. Because A-to-I editing may affect base-pairing and RNA structure, processes including... mehr

    Niedersächsische Staats- und Universitätsbibliothek Göttingen
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    Universitäts- und Landesbibliothek Sachsen-Anhalt / Zentrale
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    Bibliotheks-und Informationssystem der Carl von Ossietzky Universität Oldenburg (BIS)
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    Universität Potsdam, Universitätsbibliothek
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    The objective of this CTMI volume is to provide readers with a foundation for understanding what ADARs are and how they act to affect gene expression and function. Because A-to-I editing may affect base-pairing and RNA structure, processes including translation, splicing, RNA replication, and miR and siRNA silencing may be affected.¡ It also is becoming increasingly apparent that ADARs may possess roles not only as enzymes that deaminate adenosine to produce inosine in RNA substrates with double-stranded character, but also as proteins independent of their catalytic property. Future studies of ADARs no doubt will provide us with additional surprises and new insights into the modulation of biological processes by the ADAR family of proteins The objective of this "CTMI" volume is to provide readers with a foundation for understanding what ADARs are and how they act to affect gene expression and function. It is becoming increasingly apparent that ADARs may possess roles not only as enzymes that deaminate adenosine to produce inosine in RNA substrates with double-stranded character, but also as proteins independent of their catalytic property. Because A-to-I editing may affect base-pairing and RNA structure, processes including translation, splicing, RNA replication, and miR and siRNA silencing may be affected. Future stud

     

    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Hinweise zum Inhalt
    Volltext (lizenzpflichtig)
    Quelle: Verbundkataloge
    Sprache: Englisch
    Medientyp: Ebook
    Format: Online
    ISBN: 9783642228018
    Weitere Identifier:
    RVK Klassifikation: WD 5065
    Schriftenreihe: Current Topics in Microbiology and Immunology ; 353
    Schlagworte: Medicine; Human physiology; Adenosine Deaminase; RNA Editing; RNA, Double-Stranded
    Umfang: Online-Ressource, v.: digital
    Bemerkung(en):

    Description based upon print version of record

    Electronic reproduction; Available via World Wide Web

    Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing; Preface; Contents; Contributors; 144 ADAR Proteins: Structure and Catalytic Mechanism; Abstract; 1…The Reaction Catalyzed by ADARs; 2…The ADAR Protein Structure is Modular; 3…Overview of Structure of ADAR2 Deaminase Domain; 4…H394, C451, C516: Zn2+ Binding; 4.1 E396; 4.2 T375; 4.3 R455; 5…Residues Involved in IP6 Binding; 6…Roles of Functional Groups in RNA Substrate at or Near the Deamination Site; 7…The Effect of Helix Defects; 8…Preferred Flanking Sequence; 9…A--C Mismatch at Editing Site

    10…2vprime-Hydroxyl of the Edited Nucleoside11…8-Aza Substitution at Edited Adenosine; 12…N7 of Substrate, C7 Substituents on Adenosine Analogs; 13…C6- and C2-Positions of the Edited Purine; 13.1 The ADAR Reaction Mechanism; 13.2 Dimerization; 13.3 Substrate Binding and Conformational Changes; 13.4 Deamination in the ADAR Active Site and Product Release; Acknowledgments; References; 145 ADAR Proteins: Double-stranded RNA and Z-DNA Binding Domains; Abstract; 1…Introduction; 2…Adenosine Deaminases Acting on RNA Family Members and Their Domain Organization; 3…RNA Editing Substrate

    3.1 Specificity of Editing3.2 What Makes a Good Editing Site?; 3.2.1 Preferences; 3.2.2 Selectivity; 3.3 Structures of Editing Substrates; 4…Adenosine Deaminases Acting on RNA Z-DNA Binding Domains; 4.1 Z-DNA Binding Domain: Structure and Substrate Recognition; 4.2 A Role for ADAR1 Z alpha Domain?; 4.3 How Does a Z-DNA Binding Domain Bind to Z-DNA?; 4.4 ADAR1 Z beta Domain: a Domain for Protein--Protein Interaction?; 5…Adenosine Deaminases Acting on RNA dsRNA Binding Domains; 5.1 Structural Characteristics of a dsRNA Binding Domain; 5.2 Sequence Specific Recognition with dsRBD

    5.3 How dsRBDs are Positioned on Substrate?5.4 Are the Binding Sites of ADAR dsRBDs Predictable?; 6…dsRBDs and Z-DNA Binding Domains Act on the Subcellular Localization of ADARs; 7…Concluding Remarks; Acknowledgments; References; 157 Editing of Neurotransmitter Receptor and Ion Channel RNAs in the Nervous System; Abstract; 1…Introduction; 2…Identification of A-to-I Editing Targets; 3…Mammalian ADAR Enzymes; 4…ADAR Substrates in the Central Nervous System; 4.1 Glutamate-Gated Ion Channels; 4.1.1 AMPA Receptors; 4.1.2 Kainate Receptors; 4.2 The Serotonin 2C Receptor (5HT2C)

    4.3 The alpha 3 Subunit of the GABAA Receptor (Gabra3)4.4 Voltage-gated Potassium Channel (Kv1.1); 5…Conclusions; References; 151 Modulation of MicroRNA Expression and Function by ADARs; Abstract; 1…Introduction; 2…MiRNA Biogenesis and Function; 3…Editing of MiRNAs; 3.1 Identification of Pri-MiRNA Editing Sites; 3.1.1 Systematic Surveys for MiRNA Editing Sites; 3.1.2 High-Throughput Sequencing of Mature MiRNAs; 3.2 Consequences of Pri-MiRNA Editing; 3.2.1 Effect on Drosha Cleavage; 3.2.2 Degradation of Inosine-Containing Pri-MiRNAs; 3.2.3 Effect on Dicer Cleavage; 3.2.4 Effect on RISC Loading

    3.2.5 Effect on Mature MiRNA Function

  4. Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing
    Erschienen: 2012
    Verlag:  Springer-Verlag Berlin Heidelberg, Berlin, Heidelberg

    The objective of this CTMI volume is to provide readers with a foundation for understanding what ADARs are and how they act to affect gene expression and function. Because A-to-I editing may affect base-pairing and RNA structure, processes including... mehr

    Universitätsbibliothek Freiburg
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    Niedersächsische Staats- und Universitätsbibliothek Göttingen
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    Universitäts- und Landesbibliothek Sachsen-Anhalt / Zentrale
    ebook
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    Bibliotheks-und Informationssystem der Carl von Ossietzky Universität Oldenburg (BIS)
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    Universität Potsdam, Universitätsbibliothek
    keine Fernleihe

     

    The objective of this CTMI volume is to provide readers with a foundation for understanding what ADARs are and how they act to affect gene expression and function. Because A-to-I editing may affect base-pairing and RNA structure, processes including translation, splicing, RNA replication, and miR and siRNA silencing may be affected.¡ It also is becoming increasingly apparent that ADARs may possess roles not only as enzymes that deaminate adenosine to produce inosine in RNA substrates with double-stranded character, but also as proteins independent of their catalytic property. Future studies of ADARs no doubt will provide us with additional surprises and new insights into the modulation of biological processes by the ADAR family of proteins The objective of this "CTMI" volume is to provide readers with a foundation for understanding what ADARs are and how they act to affect gene expression and function. It is becoming increasingly apparent that ADARs may possess roles not only as enzymes that deaminate adenosine to produce inosine in RNA substrates with double-stranded character, but also as proteins independent of their catalytic property. Because A-to-I editing may affect base-pairing and RNA structure, processes including translation, splicing, RNA replication, and miR and siRNA silencing may be affected. Future stud

     

    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Hinweise zum Inhalt
    Volltext (lizenzpflichtig)
    Quelle: Verbundkataloge
    Sprache: Englisch
    Medientyp: Ebook
    Format: Online
    ISBN: 9783642228018
    Weitere Identifier:
    RVK Klassifikation: WD 5065
    Schriftenreihe: Current Topics in Microbiology and Immunology ; 353
    Array
    Schlagworte: Medicine; Human physiology; Biomedicine; Medicine; Human physiology; Adenosine Deaminase; RNA Editing; RNA, Double-Stranded
    Weitere Schlagworte: Double-stranded RNA; Adenosine deaminase
    Umfang: Online-Ressource (X, 238p. 50 illus., 28 illus. in color, digital)
    Bemerkung(en):

    Description based upon print version of record

    Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing; Preface; Contents; Contributors; 144 ADAR Proteins: Structure and Catalytic Mechanism; Abstract; 1…The Reaction Catalyzed by ADARs; 2…The ADAR Protein Structure is Modular; 3…Overview of Structure of ADAR2 Deaminase Domain; 4…H394, C451, C516: Zn2+ Binding; 4.1 E396; 4.2 T375; 4.3 R455; 5…Residues Involved in IP6 Binding; 6…Roles of Functional Groups in RNA Substrate at or Near the Deamination Site; 7…The Effect of Helix Defects; 8…Preferred Flanking Sequence; 9…A--C Mismatch at Editing Site

    10…2vprime-Hydroxyl of the Edited Nucleoside11…8-Aza Substitution at Edited Adenosine; 12…N7 of Substrate, C7 Substituents on Adenosine Analogs; 13…C6- and C2-Positions of the Edited Purine; 13.1 The ADAR Reaction Mechanism; 13.2 Dimerization; 13.3 Substrate Binding and Conformational Changes; 13.4 Deamination in the ADAR Active Site and Product Release; Acknowledgments; References; 145 ADAR Proteins: Double-stranded RNA and Z-DNA Binding Domains; Abstract; 1…Introduction; 2…Adenosine Deaminases Acting on RNA Family Members and Their Domain Organization; 3…RNA Editing Substrate

    3.1 Specificity of Editing3.2 What Makes a Good Editing Site?; 3.2.1 Preferences; 3.2.2 Selectivity; 3.3 Structures of Editing Substrates; 4…Adenosine Deaminases Acting on RNA Z-DNA Binding Domains; 4.1 Z-DNA Binding Domain: Structure and Substrate Recognition; 4.2 A Role for ADAR1 Z alpha Domain?; 4.3 How Does a Z-DNA Binding Domain Bind to Z-DNA?; 4.4 ADAR1 Z beta Domain: a Domain for Protein--Protein Interaction?; 5…Adenosine Deaminases Acting on RNA dsRNA Binding Domains; 5.1 Structural Characteristics of a dsRNA Binding Domain; 5.2 Sequence Specific Recognition with dsRBD

    5.3 How dsRBDs are Positioned on Substrate?5.4 Are the Binding Sites of ADAR dsRBDs Predictable?; 6…dsRBDs and Z-DNA Binding Domains Act on the Subcellular Localization of ADARs; 7…Concluding Remarks; Acknowledgments; References; 157 Editing of Neurotransmitter Receptor and Ion Channel RNAs in the Nervous System; Abstract; 1…Introduction; 2…Identification of A-to-I Editing Targets; 3…Mammalian ADAR Enzymes; 4…ADAR Substrates in the Central Nervous System; 4.1 Glutamate-Gated Ion Channels; 4.1.1 AMPA Receptors; 4.1.2 Kainate Receptors; 4.2 The Serotonin 2C Receptor (5HT2C)

    4.3 The alpha 3 Subunit of the GABAA Receptor (Gabra3)4.4 Voltage-gated Potassium Channel (Kv1.1); 5…Conclusions; References; 151 Modulation of MicroRNA Expression and Function by ADARs; Abstract; 1…Introduction; 2…MiRNA Biogenesis and Function; 3…Editing of MiRNAs; 3.1 Identification of Pri-MiRNA Editing Sites; 3.1.1 Systematic Surveys for MiRNA Editing Sites; 3.1.2 High-Throughput Sequencing of Mature MiRNAs; 3.2 Consequences of Pri-MiRNA Editing; 3.2.1 Effect on Drosha Cleavage; 3.2.2 Degradation of Inosine-Containing Pri-MiRNAs; 3.2.3 Effect on Dicer Cleavage; 3.2.4 Effect on RISC Loading

    3.2.5 Effect on Mature MiRNA Function

  5. Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing
    Erschienen: 2012
    Verlag:  Springer-Verlag Berlin Heidelberg, Berlin, Heidelberg

    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: Verbundkataloge
    Sprache: Englisch
    Medientyp: Ebook
    Format: Online
    ISBN: 9783642228018
    Weitere Identifier:
    Schriftenreihe: Current Topics in Microbiology and Immunology ; 353
    Schlagworte: Medicine; Human physiology
  6. Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing
    Erschienen: 2012
    Verlag:  Springer-Verlag Berlin Heidelberg, Berlin, Heidelberg

    The objective of this CTMI volume is to provide readers with a foundation for understanding what ADARs are and how they act to affect gene expression and function. Because A-to-I editing may affect base-pairing and RNA structure, processes including... mehr

    Universität Potsdam, Universitätsbibliothek
    uneingeschränkte Fernleihe, Kopie und Ausleihe

     

    The objective of this CTMI volume is to provide readers with a foundation for understanding what ADARs are and how they act to affect gene expression and function. Because A-to-I editing may affect base-pairing and RNA structure, processes including translation, splicing, RNA replication, and miR and siRNA silencing may be affected.¡ It also is becoming increasingly apparent that ADARs may possess roles not only as enzymes that deaminate adenosine to produce inosine in RNA substrates with double-stranded character, but also as proteins independent of their catalytic property. Future studies of ADARs no doubt will provide us with additional surprises and new insights into the modulation of biological processes by the ADAR family of proteins The objective of this "CTMI" volume is to provide readers with a foundation for understanding what ADARs are and how they act to affect gene expression and function. It is becoming increasingly apparent that ADARs may possess roles not only as enzymes that deaminate adenosine to produce inosine in RNA substrates with double-stranded character, but also as proteins independent of their catalytic property. Because A-to-I editing may affect base-pairing and RNA structure, processes including translation, splicing, RNA replication, and miR and siRNA silencing may be affected. Future stud

     

    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Hinweise zum Inhalt
    Volltext (lizenzpflichtig)
    Quelle: Verbundkataloge
    Sprache: Englisch
    Medientyp: Ebook
    Format: Online
    ISBN: 9783642228018
    Weitere Identifier:
    RVK Klassifikation: WD 5065
    Schriftenreihe: Current Topics in Microbiology and Immunology ; 353
    Array
    Schlagworte: Medicine; Human physiology; Biomedicine; Medicine; Human physiology; Adenosine Deaminase; RNA Editing; RNA, Double-Stranded
    Weitere Schlagworte: Double-stranded RNA; Adenosine deaminase
    Umfang: Online-Ressource (X, 238p. 50 illus., 28 illus. in color, digital)
    Bemerkung(en):

    Description based upon print version of record

    Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing; Preface; Contents; Contributors; 144 ADAR Proteins: Structure and Catalytic Mechanism; Abstract; 1…The Reaction Catalyzed by ADARs; 2…The ADAR Protein Structure is Modular; 3…Overview of Structure of ADAR2 Deaminase Domain; 4…H394, C451, C516: Zn2+ Binding; 4.1 E396; 4.2 T375; 4.3 R455; 5…Residues Involved in IP6 Binding; 6…Roles of Functional Groups in RNA Substrate at or Near the Deamination Site; 7…The Effect of Helix Defects; 8…Preferred Flanking Sequence; 9…A--C Mismatch at Editing Site

    10…2vprime-Hydroxyl of the Edited Nucleoside11…8-Aza Substitution at Edited Adenosine; 12…N7 of Substrate, C7 Substituents on Adenosine Analogs; 13…C6- and C2-Positions of the Edited Purine; 13.1 The ADAR Reaction Mechanism; 13.2 Dimerization; 13.3 Substrate Binding and Conformational Changes; 13.4 Deamination in the ADAR Active Site and Product Release; Acknowledgments; References; 145 ADAR Proteins: Double-stranded RNA and Z-DNA Binding Domains; Abstract; 1…Introduction; 2…Adenosine Deaminases Acting on RNA Family Members and Their Domain Organization; 3…RNA Editing Substrate

    3.1 Specificity of Editing3.2 What Makes a Good Editing Site?; 3.2.1 Preferences; 3.2.2 Selectivity; 3.3 Structures of Editing Substrates; 4…Adenosine Deaminases Acting on RNA Z-DNA Binding Domains; 4.1 Z-DNA Binding Domain: Structure and Substrate Recognition; 4.2 A Role for ADAR1 Z alpha Domain?; 4.3 How Does a Z-DNA Binding Domain Bind to Z-DNA?; 4.4 ADAR1 Z beta Domain: a Domain for Protein--Protein Interaction?; 5…Adenosine Deaminases Acting on RNA dsRNA Binding Domains; 5.1 Structural Characteristics of a dsRNA Binding Domain; 5.2 Sequence Specific Recognition with dsRBD

    5.3 How dsRBDs are Positioned on Substrate?5.4 Are the Binding Sites of ADAR dsRBDs Predictable?; 6…dsRBDs and Z-DNA Binding Domains Act on the Subcellular Localization of ADARs; 7…Concluding Remarks; Acknowledgments; References; 157 Editing of Neurotransmitter Receptor and Ion Channel RNAs in the Nervous System; Abstract; 1…Introduction; 2…Identification of A-to-I Editing Targets; 3…Mammalian ADAR Enzymes; 4…ADAR Substrates in the Central Nervous System; 4.1 Glutamate-Gated Ion Channels; 4.1.1 AMPA Receptors; 4.1.2 Kainate Receptors; 4.2 The Serotonin 2C Receptor (5HT2C)

    4.3 The alpha 3 Subunit of the GABAA Receptor (Gabra3)4.4 Voltage-gated Potassium Channel (Kv1.1); 5…Conclusions; References; 151 Modulation of MicroRNA Expression and Function by ADARs; Abstract; 1…Introduction; 2…MiRNA Biogenesis and Function; 3…Editing of MiRNAs; 3.1 Identification of Pri-MiRNA Editing Sites; 3.1.1 Systematic Surveys for MiRNA Editing Sites; 3.1.2 High-Throughput Sequencing of Mature MiRNAs; 3.2 Consequences of Pri-MiRNA Editing; 3.2.1 Effect on Drosha Cleavage; 3.2.2 Degradation of Inosine-Containing Pri-MiRNAs; 3.2.3 Effect on Dicer Cleavage; 3.2.4 Effect on RISC Loading

    3.2.5 Effect on Mature MiRNA Function

  7. Beyond the body proper
    reading the anthropology of material life
    Beteiligt: Lock, Margaret M. (HerausgeberIn); Farquhar, Judith (HerausgeberIn)
    Erschienen: 2007
    Verlag:  Duke Univ. Press, Durham, N.C. [u.a.]

    An emergent canon, or putting bodies on the scholarly agenda -- Introduction -- Friedrich Engels on the part played by labor in the transition from ape to man / Robert Hertz -- The pre-eminence of the right hand / Marcel Granet --Right and left in... mehr

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    An emergent canon, or putting bodies on the scholarly agenda -- Introduction -- Friedrich Engels on the part played by labor in the transition from ape to man / Robert Hertz -- The pre-eminence of the right hand / Marcel Granet --Right and left in China / Marcel Mauss -- Techniques of the body / Victor Turner --Symbols in Ndembu ritual / Terence Turner -- The social skin -- Philosophical studies, or learning how to think embodiment -- Introduction -- Karl Marx and opposition of the materialist and idealist outlook / Friedrich Engels -- Walter Benjamin on the mimetic faculty / Maurice Merleau-Ponty -- From the phenomenology of perception / Ian Hacking -- Making up people / Judith Butler -- From bodies that matter / Bruno Latour -- Do you believe in reality? -- Fundamental processes, or denaturalizing the given -- Introduction / E. E. Evans-Pritchard -- Time and space / Caroline WalK Bynum -- Women mystics and eucharistic devotion in the thirteenth century / Kristofer M. Schipper -- On breath / Henry Abelove -- Some speculations on the history of "sexual intercourse" during the "long eighteenth century" in England / Margaret Lock -- Human body parts as therapeutic tools : contradictory discourses and transformed subjectivities / Anna Lowenhaupt -- Tsing Meratus embryology -- Everyday life, or exploring the body's times and spaces -- Introduction to Part IV / Michel de Certeau -- Walking in the city / Michael Taussig -- Tactility and distraction / Peter Stallybrass and Allon White -- The city, the gaze, and the contaminating touch -- Judith Farquhar -- Medicinal meals / Nancy K. Miller -- Rereading as a woman : the body in practice -- Colonized bodies, or analyzing the materiality of domination -- Introduction ./ Janice Boddy --Remembering Amal : on birth and the British in Northern Sudan / Susan Pedersen -- National bodies, unspeakable acts : the sexual politics of colonial policy making / Stuart Cosgrove -- The zoot suit and style warfare -- John D. O'Neil -- Cooptation and control : the reconstruction of Inuit birth / Patricia Leyland Kaufert, Jean Langford -- Dosic bodies/docile bodies -- Desires and identities, or negotiating sex and gender -- Introduction / John Boswell -- Men, beasts, and "nature" / Gregory M. Pflugfelder -- Cartographies of desire : male-male sexuality in Japanese discourse / Emily Martin -- The egg and the sperm : how science has constructed a romance based on stereotypical male-female roles / Gilles Deleuze -- We always make love with worlds / Felix Guattari -- Bodies at the margin, or attending to distress and difference -- Introduction / Barbara Duden -- The woman beneath the skin : a doctor's patients in eighteenth-century Germany / Mariella Pandolfi-- Memory within the body : women's narrative and identity in a Southern Italian village / Nancy Scheper-Hughes -- Nervoso / Arthur Kleinman -- Somatization : the interconnections in Chinese / Joan Kl/nman -- Society among culture, depressive experiences and the meanings of pain -- Alice Domurat Dreger-- Jarring bodies : thoughts on the display of -- Unusual anatomies -- Capitalist production, or accounting the commodification of bodily life -- Introduction / E. P. Thompson --Time, work-discipline, and industrial capitalism / Aihwa Ong --The production of possession : spirits and the multinational corporation in Malaysia / Brad Weiss plastic teeth extraction : the iconography of Haya gastro-sexual affliction -- Matthew Schmidt and constructing a "good catch," picking a winner / Lisa Jean Moore -- The development of technosemen and the deconstruction of the monolithic male / Margaret Lock -- Alienation of body parts and the biopolitics of immortalized cell lines -- Knowing systems, or tracking the bodies of the biosciences -- Introduction / Shigehisa Kuriyama -- Pulse diagnosis in the Greek and Chinese traditions / Rayna Rapp -- Real-time fetus : the role of the sonogram in the age of monitored reproduction / Charis Thompson -- Quit sniveling, cryo-baby, we'll work out which one's your mama! / Jos van Dijck -- Bodyworlds : the art of plastinated cadavers / Keith Wailoo -- Inventing the heterozygote : molecular biology, racial identity, and the narratives of sickle-cell disease / Tay-Sachs, and cystic fibrosis

     

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    Quelle: Staatsbibliothek zu Berlin
    Beteiligt: Lock, Margaret M. (HerausgeberIn); Farquhar, Judith (HerausgeberIn)
    Sprache: Englisch
    Medientyp: Buch (Monographie)
    Format: Druck
    ISBN: 9780822338307; 9780822338451; 0822338459; 0822338300
    Weitere Identifier:
    9780822338451
    RVK Klassifikation: EC 5410 ; MS 9350 ; LC 59000 ; LC 10000
    Schriftenreihe: Body, commodity, text
    Schlagworte: Human body; Human physiology; Physical anthropology; Human body; Medical anthropology; Körper; Anthropologie; Aufsatzsammlung; Body, Human; Human physiology; Physical anthropology; Body, Human; Medical anthropology
    Umfang: 688 S.
    Bemerkung(en):

    Includes bibliographical references and index

  8. Beyond the body proper
    reading the anthropology of material life
    Beteiligt: Lock, Margaret M. (HerausgeberIn); Farquhar, Judith (HerausgeberIn)
    Erschienen: 2007
    Verlag:  Duke Univ. Press, Durham, N.C. [u.a.]

    An emergent canon, or putting bodies on the scholarly agenda -- Introduction -- Friedrich Engels on the part played by labor in the transition from ape to man / Robert Hertz -- The pre-eminence of the right hand / Marcel Granet --Right and left in... mehr

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    An emergent canon, or putting bodies on the scholarly agenda -- Introduction -- Friedrich Engels on the part played by labor in the transition from ape to man / Robert Hertz -- The pre-eminence of the right hand / Marcel Granet --Right and left in China / Marcel Mauss -- Techniques of the body / Victor Turner --Symbols in Ndembu ritual / Terence Turner -- The social skin -- Philosophical studies, or learning how to think embodiment -- Introduction -- Karl Marx and opposition of the materialist and idealist outlook / Friedrich Engels -- Walter Benjamin on the mimetic faculty / Maurice Merleau-Ponty -- From the phenomenology of perception / Ian Hacking -- Making up people / Judith Butler -- From bodies that matter / Bruno Latour -- Do you believe in reality? -- Fundamental processes, or denaturalizing the given -- Introduction / E. E. Evans-Pritchard -- Time and space / Caroline WalK Bynum -- Women mystics and eucharistic devotion in the thirteenth century / Kristofer M. Schipper -- On breath / Henry Abelove -- Some speculations on the history of "sexual intercourse" during the "long eighteenth century" in England / Margaret Lock -- Human body parts as therapeutic tools : contradictory discourses and transformed subjectivities / Anna Lowenhaupt -- Tsing Meratus embryology -- Everyday life, or exploring the body's times and spaces -- Introduction to Part IV / Michel de Certeau -- Walking in the city / Michael Taussig -- Tactility and distraction / Peter Stallybrass and Allon White -- The city, the gaze, and the contaminating touch -- Judith Farquhar -- Medicinal meals / Nancy K. Miller -- Rereading as a woman : the body in practice -- Colonized bodies, or analyzing the materiality of domination -- Introduction ./ Janice Boddy --Remembering Amal : on birth and the British in Northern Sudan / Susan Pedersen -- National bodies, unspeakable acts : the sexual politics of colonial policy making / Stuart Cosgrove -- The zoot suit and style warfare -- John D. O'Neil -- Cooptation and control : the reconstruction of Inuit birth / Patricia Leyland Kaufert, Jean Langford -- Dosic bodies/docile bodies -- Desires and identities, or negotiating sex and gender -- Introduction / John Boswell -- Men, beasts, and "nature" / Gregory M. Pflugfelder -- Cartographies of desire : male-male sexuality in Japanese discourse / Emily Martin -- The egg and the sperm : how science has constructed a romance based on stereotypical male-female roles / Gilles Deleuze -- We always make love with worlds / Felix Guattari -- Bodies at the margin, or attending to distress and difference -- Introduction / Barbara Duden -- The woman beneath the skin : a doctor's patients in eighteenth-century Germany / Mariella Pandolfi-- Memory within the body : women's narrative and identity in a Southern Italian village / Nancy Scheper-Hughes -- Nervoso / Arthur Kleinman -- Somatization : the interconnections in Chinese / Joan Kl/nman -- Society among culture, depressive experiences and the meanings of pain -- Alice Domurat Dreger-- Jarring bodies : thoughts on the display of -- Unusual anatomies -- Capitalist production, or accounting the commodification of bodily life -- Introduction / E. P. Thompson --Time, work-discipline, and industrial capitalism / Aihwa Ong --The production of possession : spirits and the multinational corporation in Malaysia / Brad Weiss plastic teeth extraction : the iconography of Haya gastro-sexual affliction -- Matthew Schmidt and constructing a "good catch," picking a winner / Lisa Jean Moore -- The development of technosemen and the deconstruction of the monolithic male / Margaret Lock -- Alienation of body parts and the biopolitics of immortalized cell lines -- Knowing systems, or tracking the bodies of the biosciences -- Introduction / Shigehisa Kuriyama -- Pulse diagnosis in the Greek and Chinese traditions / Rayna Rapp -- Real-time fetus : the role of the sonogram in the age of monitored reproduction / Charis Thompson -- Quit sniveling, cryo-baby, we'll work out which one's your mama! / Jos van Dijck -- Bodyworlds : the art of plastinated cadavers / Keith Wailoo -- Inventing the heterozygote : molecular biology, racial identity, and the narratives of sickle-cell disease / Tay-Sachs, and cystic fibrosis

     

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    Hinweise zum Inhalt
    Quelle: Staatsbibliothek zu Berlin
    Beteiligt: Lock, Margaret M. (HerausgeberIn); Farquhar, Judith (HerausgeberIn)
    Sprache: Englisch
    Medientyp: Buch (Monographie)
    Format: Druck
    ISBN: 9780822338307; 9780822338451; 0822338459; 0822338300
    Weitere Identifier:
    9780822338451
    RVK Klassifikation: EC 5410 ; MS 9350 ; LC 59000 ; LC 10000
    Schriftenreihe: Body, commodity, text
    Schlagworte: Human body; Human physiology; Physical anthropology; Human body; Medical anthropology; Körper; Anthropologie; Aufsatzsammlung; Body, Human; Human physiology; Physical anthropology; Body, Human; Medical anthropology
    Umfang: 688 S.
    Bemerkung(en):

    Includes bibliographical references and index

  9. Das Gesicht der Welt
    physiognomisches Denken in der Goethezeit
    Erschienen: 1993
    Verlag:  Fink, München

    Freie Universität Berlin, Universitätsbibliothek
    uneingeschränkte Fernleihe, Kopie und Ausleihe
    TU Berlin, Universitätsbibliothek
    uneingeschränkte Fernleihe, Kopie und Ausleihe
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  10. Das Gesicht der Welt
    physiognomisches Denken in der Goethezeit
    Erschienen: 1993
    Verlag:  Fink, München

    Freie Universität Berlin, Universitätsbibliothek
    uneingeschränkte Fernleihe, Kopie und Ausleihe
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    uneingeschränkte Fernleihe, Kopie und Ausleihe
    TU Berlin, Universitätsbibliothek
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  11. Das Gesicht der Welt
    physiognomisches Denken in der Goethezeit
    Erschienen: 1993
    Verlag:  Fink, München

    Stadtarchiv Augsburg
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  12. Der menschliche Körper
    Erschienen: 2005
    Verlag:  Tessloff, Nürnberg

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    Quelle: Verbundkataloge
    Sprache: Deutsch
    Medientyp: Buch (Monographie)
    ISBN: 3788629002
    Schriftenreihe: Was ist was ; 50
    Schlagworte: Anatomie; Physiologie; Human anatomy; Human body; Human physiology; Körper
    Umfang: 48 S., zahlr. Ill.
  13. Head to toe science
    over 40 eye-popping, spine-tingling, heart-pounding activities that teach kids about the human body
    Autor*in: Wiese, Jim
    Erschienen: 2000
    Verlag:  Jossey-Bass, San Francisco, Calif.

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    Quelle: Verbundkataloge
    Sprache: Englisch
    Medientyp: Buch (Monographie)
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    ISBN: 0471332038
    Schlagworte: Human physiology; Body, Human; Science projects
    Umfang: VIII, 120 S., Ill., 26 cm.
  14. The body as interface
    dialogues between the disciplines ; [based on a conference ...took place at the Rheinische Friedrich-Wilhelms-Universität Bonn from 24 to 26 June 2003]
    Beteiligt: Sielke, Sabine (Hrsg.)
    Erschienen: 2007
    Verlag:  Winter, Heidelberg

    Staatsbibliothek zu Berlin - Preußischer Kulturbesitz, Haus Unter den Linden
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    Quelle: Staatsbibliothek zu Berlin
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    Sprache: Englisch
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    Format: Druck
    ISBN: 3825353915; 9783825353919
    Weitere Identifier:
    9783825353919
    RVK Klassifikation: EC 5410
    Schriftenreihe: American studies ; Vol.150
    Schlagworte: Human body; Mind and body; Human physiology
    Umfang: 338 S., Ill., graph. Darst., 22 cm
    Bemerkung(en):

    Literaturangaben

  15. The body as interface
    dialogues between the disciplines
    Erschienen: 2007
    Verlag:  Winter, Heidelberg

    Freie Universität Berlin, Universitätsbibliothek
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    Quelle: Philologische Bibliothek, FU Berlin; Staatsbibliothek zu Berlin
    Beteiligt: Sielke, Sabine (Hrsg.); Schäfer-Wünsche, Elisabeth (Hrsg.)
    Sprache: Englisch
    Medientyp: Buch (Monographie)
    ISBN: 9783825353919
    RVK Klassifikation: CC 6600 ; CC 7264 ; CC 7265 ; EC 1876 ; EC 5410
    Schriftenreihe: American studies ; 150
    Schlagworte: Gesellschaft; Human body; Human physiology; Mind and body; Interdisziplinäre Forschung; Körper
    Umfang: 338 S., Ill., graph. Darst.
  16. The body as interface
    dialogues between the disciplines
    Erschienen: 2007
    Verlag:  Winter, Heidelberg

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    Beteiligt: Sielke, Sabine (Hrsg.); Schäfer-Wünsche, Elisabeth (Hrsg.)
    Sprache: Englisch
    Medientyp: Buch (Monographie)
    ISBN: 9783825353919
    RVK Klassifikation: CC 6600 ; CC 7264 ; CC 7265 ; EC 1876 ; EC 5410
    Schriftenreihe: American studies ; 150
    Schlagworte: Gesellschaft; Human body; Human physiology; Mind and body; Interdisziplinäre Forschung; Körper
    Umfang: 338 S., Ill., graph. Darst.
  17. The body as interface
    dialogues between the disciplines ; [based on a conference ...took place at the Rheinische Friedrich-Wilhelms-Universität Bonn from 24 to 26 June 2003]
    Beteiligt: Sielke, Sabine (Hrsg.)
    Erschienen: 2007
    Verlag:  Winter, Heidelberg

    Max-Planck-Institut für Wissenschaftsgeschichte, Bibliothek
    128 B6685
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    Sprache: Englisch
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    ISBN: 3825353915; 9783825353919
    Weitere Identifier:
    9783825353919
    RVK Klassifikation: EC 5410
    Schriftenreihe: American studies ; Vol.150
    Schlagworte: Human body; Mind and body; Human physiology
    Umfang: 338 S., Ill., graph. Darst., 22 cm
    Bemerkung(en):

    Literaturangaben

  18. ˜Dasœ Gesicht der Welt : physiognomisches Denken in der Goethezeit
    Erschienen: 1993
    Verlag:  München : Fink

    Johannes Saltzwedel ; Volltext // Exemplar mit der Signatur: München, Bayerische Staatsbibliothek -- 2009.58266 mehr

     

    Johannes Saltzwedel ; Volltext // Exemplar mit der Signatur: München, Bayerische Staatsbibliothek -- 2009.58266

     

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    Medientyp: Buch (Monographie)
    Format: Online
    Weitere Identifier:
    ftbsbmuenchendc:oai:bdr.oai.bsb-muenchen.de:all:BDR-BV006194121-60963
    Weitere Schlagworte: Novalis; Goethe; Johann Wolfgang von; Lavater; Johann Caspar; Herder; Johann Gottfried von; Geschichte 1700-1800; Geschichte 1800-1900; Geschichte 1775-1825; Geschichte 1750-1869; Geschichte 1750-1830; Fysiognomiek; Geschichte; Body and soul in literature; Characters and characteristics in literature; German literature; History and criticism; 18th century; 19th century; Human physiology; History; Ästhetik; Physiognomik; Physiognomie; Deutschland
    Umfang: Online-Ressource
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    Datenlieferant: Bavarian Digital Repository (BDR - Bayerische Staatsbibliothek Munich, BSB)