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  1. Does retirement affect secondary preventive care use?
    evidence from breast cancer screening
    Autor*in: Eibich, Peter; Goldzahl, Léontine
    Erschienen: [2020]
    Verlag:  Max Planck Institute for Demographic Research, Rostock, Germany

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    Standort:
    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
    Signatur:
    VS 473
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    keine Fernleihe
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    Quelle: Verbundkataloge
    Sprache: Englisch
    Medientyp: Buch (Monographie)
    Format: Online
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    Schriftenreihe: MPIDR working paper ; WP 2020, 011 (March 2020)
    Schlagworte: Europe; retirement; health behavior; instrumental variables; preventive care; breast cancer
    Umfang: 1 Online-Ressource (circa 50 Seiten), Illustrationen
  2. The relative value of suicide prevention in health care priority setting
    Autor*in: Andrén, Daniela; Laitila, Thomas; Ryen, Linda; Vimefall, Elin
    Erschienen: [2023]
    Verlag:  Örebro University School of Business, Örebro, Sweden

    This article investigates how the Swedish population values a reduction in the number of suicides in relation to other life-saving interventions within the health care sector. An online discrete choice experiment was conducted with a sample of 1000... mehr

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    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
    Signatur:
    DS 776
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    This article investigates how the Swedish population values a reduction in the number of suicides in relation to other life-saving interventions within the health care sector. An online discrete choice experiment was conducted with a sample of 1000 Swedish members of the web panel Userneeds to elicit the relative importance placed on reducing the number of suicides in comparison to deaths due to pancreatic cancer, breast cancer, and acute heart attack. The choice set consisted of three attributes: number of lives saved, cause of death, and age group affected. We found that respondents valued saving lives by suicide prevention lower than saving lives from pancreatic cancer, breast cancer, or acute heart attack.

     
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    Quelle: Verbundkataloge
    Sprache: Englisch
    Medientyp: Buch (Monographie)
    Format: Online
    Schriftenreihe: Array ; 2023, 10
    Schlagworte: relative value of suicide prevention; health care; priority setting; saving lives; discrete choice experiment; pancreatic cancer; breast cancer; acute heart attack
    Umfang: 1 Online-Ressource (circa 19 Seiten), Illustrationen
  3. AB186 inhibits migration of triple-negative breast cancer cells and interacts with α-tubulin
    Autor*in: Geoffroy, Marine; Lemesle, Marine; Kleinclauss, Alexandra; Mazerbourg, Sabine; Batista, Levy; Barberi-Heyob, Muriel; Bastogne, Thierry; Boireau, Wilfrid; Rouleau, Alain; Dupommier, Dorian; Boisbrun, Michel; Comoy, Corinne; Flament, Stéphane; Grillier-Vuissoz, Isabelle; Kuntz, Sandra
    Erschienen: 2022
    Verlag:  HAL CCSD ; MDPI

    International audience ; Breast cancer is one of the leading causes of cancer-related death among females worldwide. A major challenge is to develop innovative therapy in order to treat breast cancer subtypes resistant to current treatment. In the... mehr

     

    International audience ; Breast cancer is one of the leading causes of cancer-related death among females worldwide. A major challenge is to develop innovative therapy in order to treat breast cancer subtypes resistant to current treatment. In the present study, we examined the effects of two Troglitazone derivatives Δ2-TGZ and AB186. Previous studies showed that both compounds induce apoptosis, nevertheless AB186 was a more potent agent. The kinetic of cellular events was investigated by real-time cell analysis system (RTCA) in MCF-7 (hormone dependent) and MDA-MB-231 (triple negative) breast cancer (TNBC) cells, followed by cell morphology analysis by immuno-localization. Both compounds induced a rapid modification of both impedance-based signals and cellular morphology. This process was associated with an inhibition of cell migration measured by wound healing and transwell assays in TNBC MDA-MB-231 and Hs578T cells. In order to identify cytoplasmic targets of AB186, we performed surface plasmon resonance (SPR) and pull-down analyses. Subsequently, 6 cytoskeleton components were identified as potential targets. We further validated α-tubulin as one of the direct targets of AB186. In conclusion, our results suggested that AB186 could be promising to develop novel therapeutic strategies to treat aggressive forms of breast cancer such as TNBC.

     
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    Quelle: BASE Fachausschnitt AVL
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Übergeordneter Titel: ISSN: 1661-6596 ; EISSN: 1422-0067 ; International Journal of Molecular Sciences ; https://hal.science/hal-04238267 ; International Journal of Molecular Sciences, 2022, 23 (12), pp.6859. ⟨10.3390/ijms23126859⟩
    Schlagworte: cytoskeleton; tubulin; cell migration; breast cancer; troglitazone derivatives; apoptosis; [SDV.CAN]Life Sciences [q-bio]/Cancer; [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC]; [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology
    Lizenz:

    info:eu-repo/semantics/OpenAccess
  4. Improving breast cancer diagnosis pathways in Quebec
    Autor*in: Corkum, Eleanor; Perrault, Tiffanie; Strumpf, Erin
    Erschienen: [2023]
    Verlag:  CIRANO, [Montréal]

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    Standort:
    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
    Signatur:
    VS 904
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    Quelle: Verbundkataloge
    Sprache: Englisch
    Medientyp: Buch (Monographie)
    Format: Online
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    Schriftenreihe: Rapport de projet / CIRANO ; 2023RP, 22
    Schlagworte: cancer; health; public health; breast cancer; screening; healthcare performance; diagnosis
    Umfang: 1 Online-Ressource (circa 42 Seiten), Illustrationen
  5. Do medical treatments work for work?
    evidence from breast cancer patients
    Autor*in: Daysal, N. Meltem; Evans, William N.; Pedersen, Mikkel Hasse; Trandafir, Mircea
    Erschienen: February 2024
    Verlag:  CESifo, Munich, Germany

    We investigate the effects of radiation therapy on the mortality and economic outcomes of breast cancer patients. We implement a 2SLS strategy within a difference-in-difference framework exploiting variation in treatment stemming from a medical... mehr

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    DS 63
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    We investigate the effects of radiation therapy on the mortality and economic outcomes of breast cancer patients. We implement a 2SLS strategy within a difference-in-difference framework exploiting variation in treatment stemming from a medical guideline change in Denmark. Using administrative data, we reproduce results from an RCT showing the lifesaving benefits of radiotherapy. We then show therapy also has economic returns: ten years after diagnosis, treatment increases employment by 37% and earnings by 45%. Mortality and economic results are driven by results for more educated women, indicating that equalizing access to treatment may not be sufficient to reduce health inequalities.

     
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    Quelle: Verbundkataloge
    Sprache: Englisch
    Medientyp: Buch (Monographie)
    Format: Online
    Weitere Identifier:
    hdl: 10419/296051
    Schriftenreihe: CESifo working papers ; 10962 (2024)
    Schlagworte: breast cancer; medical treatments; employment; mortality
    Umfang: 1 Online-Ressource (circa 76 Seiten), Illustrationen
  6. Do medical treatments work for work?
    evidence from breast cancer patients
    Autor*in: Daysal, N. Meltem; Evans, William N.; Pedersen, Mikkel Hasse; Trandafir, Mircea
    Erschienen: February 2024
    Verlag:  IZA - Institute of Labor Economics, Bonn, Germany

    We investigate the effects of radiation therapy on the mortality and economic outcomes of breast cancer patients.We implement a 2SLS strategy within a difference-in-difference framework exploiting variation in treatment stemming from a medical... mehr

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    Verlag (kostenfrei)
    Verlag (kostenfrei)

    Standort:
    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
    Signatur:
    DS 4
    Fernleihe:
    keine Fernleihe

     

    We investigate the effects of radiation therapy on the mortality and economic outcomes of breast cancer patients.We implement a 2SLS strategy within a difference-in-difference framework exploiting variation in treatment stemming from a medical guideline change in Denmark. Using administrative data, we reproduce results from an RCT showing the lifesaving benefits of radiotherapy. We then show therapy also has economic returns: ten years after diagnosis, treatment increases employment by 37% and earnings by 45%. Mortality and economic results are driven by results for more educated women, indicating that equalizing access to treatment may not be sufficient to reduce health inequalities.

     
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    Quelle: Verbundkataloge
    Sprache: Englisch
    Medientyp: Buch (Monographie)
    Format: Online
    Schriftenreihe: Discussion paper series / IZA ; no. 16810
    Schlagworte: breast cancer; medical treatments; employment; mortality
    Umfang: 1 Online-Ressource (circa 76 Seiten), Illustrationen
  7. Affordable care act and disparities in health services utilization among ethnic minoritiy breast cancer survivors
    evidence from longitudinal medical expenditure panel surveys 2008-2015
    Autor*in: White-Means, Shelley I.; Osmani, Ahmad Reshad
    Erschienen: [2018]
    Verlag:  ZBW, [Kiel

    Breast cancer is the most prevalent female cancer in the US. Incidence rates are similar for white and black women, but mortality rates are higher for black women. Scant evidence exists on how heath care reform policies differentially affect the use... mehr

    Standort:
    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
    Signatur:
    DSM
    Fernleihe:
    keine Fernleihe

     

    Breast cancer is the most prevalent female cancer in the US. Incidence rates are similar for white and black women, but mortality rates are higher for black women. Scant evidence exists on how heath care reform policies differentially affect the use of health care services among racial/ethnic minority breast cancer survivors in the US. This study draws on rich, nationally representative data, the 2008-2015 Medical Expenditure Panel Surveys, to estimate effects of the Affordable Care Act (ACA) on reducing disparities in and access to use of diagnostic and medical services for black and Hispanic breast cancer survivors. Random effects multinomial logit, flexible hurdle, and Box-Cox estimation techniques are used. The robust estimates indicate that the ACA narrowed the racial/ethnic disparity in health insurance among breast cancer survivors. Gaps in mammography use significantly declined post-ACA for Hispanic breast cancer survivors compared with white and black survivors. The ACA did not significantly impact disparities in physician utilization. Out-of-pocket prescription drug expenditures declined, narrowing the gap for black and Hispanic survivors. The paper concludes with a discussion of the strengths and limitations of the ACA for reducing disparities and improving health outcomes for a growing population of breast cancer survivors in the US.

     
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    Hinweise zum Inhalt
    Volltext (kostenfrei)
    Volltext (kostenfrei)
    Quelle: Verbundkataloge
    Sprache: Englisch
    Medientyp: Buch (Monographie)
    Format: Online
    Weitere Identifier:
    hdl: 10419/184648
    Übergeordneter Titel: Sonderdruck aus: International journal of environmental research and public health; Basel : MDPI AG, 2004-; volume 15 (2018) issue 9, 26 Seiten
    Schlagworte: disparities; breast cancer; box-cox transformation; flexible hurdle model; health care system influence
    Umfang: 1 Online-Ressource (circa 27 Seiten), Illustrationen