Ergebnisse für *

Zeige Ergebnisse 1 bis 3 von 3.

  1. Repeated kidney re-transplantation - the Eurotransplant experience: a retrospective multicenter outcome analysis
    Erschienen: 2020
    Verlag:  Wiley-Blackwell, Oxford [u.a.] ; Albert-Ludwigs-Universität Freiburg, Freiburg

    Zugang:
    Resolving-System (kostenfrei)
    Resolving-System (kostenfrei)
    Universitätsbibliothek Freiburg
    keine Fernleihe
    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: Verbundkataloge
    Sprache: Englisch
    Medientyp: Aufsatz aus einer Zeitschrift
    Format: Online
    Weitere Identifier:
    FRUB-opus-166472
    Übergeordneter Titel: Sonderdruck aus: Transplant international; 33, 6 (2020), 617-631
    Schlagworte: Zuteilung; Kind; Transplantat; Niere; Transplantatabstoßung; Wiederholung; Überleben
    Umfang: 1 Online-Ressource (15 Seiten), Diagramme
    Bemerkung(en):

    Enthält eine pdf-Datei und eine zip-Datei

  2. Repeated kidney re-transplantation - the Eurotransplant experience: a retrospective multicenter outcome analysis
    Erschienen: 2020
    Verlag:  Universität, Freiburg

    Abstract: In Eurotransplant kidney allocation system (ETKAS), candidates can be considered unlimitedly for repeated re‐transplantation. Data on outcome and benefit are indeterminate. We performed a retrospective 15‐year patient and graft outcome data... mehr

     

    Abstract: In Eurotransplant kidney allocation system (ETKAS), candidates can be considered unlimitedly for repeated re‐transplantation. Data on outcome and benefit are indeterminate. We performed a retrospective 15‐year patient and graft outcome data analysis from 1464 recipients of a third or fourth or higher sequential deceased donor renal transplantation (DDRT) from 42 transplant centers. Repeated re‐DDRT recipients were younger (mean 43.0 vs. 50.2 years) compared to first DDRT recipients. They received grafts with more favorable HLA matches (89.0% vs. 84.5%) but thereby no statistically significant improvement of patient and graft outcome was found as comparatively demonstrated in 1st DDRT. In the multivariate modeling accounting for confounding factors, mortality and graft loss after 3rd and ≥4th DDRT (P < 0.001 each) and death with functioning graft (DwFG) after 3rd DDRT (P = 0.001) were higher as compared to 1st DDRT. The incidence of primary nonfunction (PNF) was also significantly higher in re‐DDRT (12.7%) than in 1st DDRT (7.1%; P < 0.001). Facing organ shortage, increasing waiting time, and considerable mortality on dialysis, we question the current policy of repeated re‐DDRT. The data from this survey propose better HLA matching in first DDRT and second DDRT and careful selection of candidates, especially for ≥4th DDRT

     

    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: Verbundkataloge
    Sprache: Englisch
    Medientyp: Buch (Monographie)
    Format: Online
    Weitere Identifier:
    Schlagworte: Zuteilung; Kind; Transplantat; Niere; Transplantatabstoßung; Wiederholung; Überleben
    Weitere Schlagworte: Fourth; Re‐transplantation; Third; (local)article
    Umfang: Online-Ressource
    Bemerkung(en):

    Transplant international. - 33, 6 (2020) , 617-631, ISSN: 1432-2277

  3. Repeated kidney re-transplantation - the Eurotransplant experience: a retrospective multicenter outcome analysis
    Erschienen: 2020
    Verlag:  Universität, Freiburg

    Abstract: In Eurotransplant kidney allocation system (ETKAS), candidates can be considered unlimitedly for repeated re‐transplantation. Data on outcome and benefit are indeterminate. We performed a retrospective 15‐year patient and graft outcome data... mehr

    Technische Hochschule Bingen, Bibliothek
    keine Fernleihe
    Bibliothek der Hochschule Darmstadt, Zentralbibliothek
    keine Fernleihe
    TU Darmstadt, Universitäts- und Landesbibliothek - Stadtmitte
    keine Fernleihe
    Bibliothek der Frankfurt University of Applied Sciences
    keine Fernleihe
    Universitätsbibliothek J. C. Senckenberg, Zentralbibliothek (ZB)
    keine Fernleihe
    Hochschul- und Landesbibliothek Fulda, Standort Heinrich-von-Bibra-Platz
    keine Fernleihe
    Technische Hochschule Mittelhessen, Hochschulbibliothek Gießen
    keine Fernleihe
    Universitätsbibliothek Gießen
    keine Fernleihe
    Universitätsbibliothek Kassel, Landesbibliothek und Murhardsche Bibliothek der Stadt Kassel
    keine Fernleihe
    Universität Mainz, Zentralbibliothek
    keine Fernleihe
    Universität Marburg, Universitätsbibliothek
    keine Fernleihe
    Hochschul- und Landesbibliothek RheinMain, Rheinstraße
    keine Fernleihe

     

    Abstract: In Eurotransplant kidney allocation system (ETKAS), candidates can be considered unlimitedly for repeated re‐transplantation. Data on outcome and benefit are indeterminate. We performed a retrospective 15‐year patient and graft outcome data analysis from 1464 recipients of a third or fourth or higher sequential deceased donor renal transplantation (DDRT) from 42 transplant centers. Repeated re‐DDRT recipients were younger (mean 43.0 vs. 50.2 years) compared to first DDRT recipients. They received grafts with more favorable HLA matches (89.0% vs. 84.5%) but thereby no statistically significant improvement of patient and graft outcome was found as comparatively demonstrated in 1st DDRT. In the multivariate modeling accounting for confounding factors, mortality and graft loss after 3rd and ≥4th DDRT (P < 0.001 each) and death with functioning graft (DwFG) after 3rd DDRT (P = 0.001) were higher as compared to 1st DDRT. The incidence of primary nonfunction (PNF) was also significantly higher in re‐DDRT (12.7%) than in 1st DDRT (7.1%; P < 0.001). Facing organ shortage, increasing waiting time, and considerable mortality on dialysis, we question the current policy of repeated re‐DDRT. The data from this survey propose better HLA matching in first DDRT and second DDRT and careful selection of candidates, especially for ≥4th DDRT

     

    Export in Literaturverwaltung   RIS-Format
      BibTeX-Format
    Quelle: Verbundkataloge
    Sprache: Englisch
    Medientyp: Buch (Monographie)
    Format: Online
    Weitere Identifier:
    DDC Klassifikation: Medizin und Gesundheit (610)
    Schlagworte: Zuteilung; Kind; Transplantat; Niere; Transplantatabstoßung; Wiederholung; Überleben
    Umfang: Online-Ressource
    Bemerkung(en):

    Transplant international

    33, 6 (2020) , 617-631, ISSN: 1432-2277