Narrow Search
Search narrowed by
Last searches

Results for *

Displaying results 1 to 25 of 44.

  1. Pandemics and firms
    drawing lessons from history
    Published: December 2020
    Publisher:  International Monetary Fund, [Washington, DC]

    The global economy is in the midst of an unprecedented slump caused by the COVID-19 pandemic. To assess the likely evolution of nonfinancial corporate performance going forward, this paper investigates empirically the impact of past pandemics using... more

    Access:
    Verlag (kostenfrei)
    Verlag (kostenfrei)
    Resolving-System (kostenfrei)
    Staatsbibliothek zu Berlin - Preußischer Kulturbesitz, Haus Unter den Linden
    Unlimited inter-library loan, copies and loan

     

    The global economy is in the midst of an unprecedented slump caused by the COVID-19 pandemic. To assess the likely evolution of nonfinancial corporate performance going forward, this paper investigates empirically the impact of past pandemics using firm-level data on more than 537,000 companies from 14 developing countries during the period 1998-2018. The analysis indicates that the prevalence of infectious diseases has an economically and statistically significant negative effect on nonfinancial corporate performance. This adverse impact is particularly pronounced on smaller and younger firms, compared to larger and more established corporations. We also find that a higher number of infectious-disease cases in population increases the probability of failure among nonfinancial firms, particularly for small and young firms. In the case of COVID-19, the magnitude of these effects will be much greater, given the unprecedented scale of the outbreak and strict policy responses to contain its spread

     

    Export to reference management software   RIS file
      BibTeX file
    Source: Staatsbibliothek zu Berlin
    Language: English
    Media type: Ebook
    Format: Online
    ISBN: 9781513563893
    Other identifier:
    Series: IMF working paper ; WP/20, 276
    Subjects: Pandemics; nonfinancial corporate performance; firm-level
    Scope: 1 Online-Ressource (circa 25 Seiten), Illustrationen
  2. Pandemics and automation
    will the lost jobs come back?
    Published: January 2021
    Publisher:  International Monetary Fund, [Washington, DC]

    Access:
    Verlag (kostenfrei)
    Resolving-System (kostenfrei)
    Staatsbibliothek zu Berlin - Preußischer Kulturbesitz, Haus Unter den Linden
    Unlimited inter-library loan, copies and loan
    Export to reference management software   RIS file
      BibTeX file
    Source: Staatsbibliothek zu Berlin
    Language: English
    Media type: Ebook
    Format: Online
    ISBN: 9781513566849
    Other identifier:
    Series: IMF working paper ; WP/21, 11
    Subjects: COVID-19; Pandemics; Robots; Inequality
    Scope: 1 Online-Ressource (circa 27 Seiten), Illustrationen
  3. Do religious people cope better in a crisis?
    evidence from the uk pandemic lockdowns
    Published: 13 February 2024
    Publisher:  Centre for Economic Policy Research, London

    We measure whether religious people in the UK cope better during a large negative shock - the nationwide pandemic lockdowns. We use data from the Understanding Society longitudinal dataset, including self-reports on religion and religiosity taken... more

    Access:
    Verlag (Deutschlandweit zugänglich)
    Verlag (Deutschlandweit zugänglich)
    Universität Potsdam, Universitätsbibliothek
    Unlimited inter-library loan, copies and loan

     

    We measure whether religious people in the UK cope better during a large negative shock - the nationwide pandemic lockdowns. We use data from the Understanding Society longitudinal dataset, including self-reports on religion and religiosity taken before the pandemic, and mental health data on unhappiness and depression, collected both before and during the lockdown periods. We find evidence that religious people coped better during the lockdowns. In terms of magnitude, we found that religious people (in that it makes a difference to their life) were around one-fifth less likely to suffer an increase in unhappiness or depression. Our results for those who belong to a religion (regardless if it makes a difference to their life) were higher in magnitude, but lower in significance. We found little difference in coping across religions; with the results for Christians, Muslims and Hindus all being broadly similar. However, we did find some difference within Christian denominations, with ‘Christian Other’ (those belonging to mainly Protestant churches other than the Church of England) coping relatively worse among those who belong to a religion. We also found that when places of worship were closed, religious Muslims and Catholics suffered disproportionately - the two religious groups in our study which normally require weekly communal attendance from their followers.

     

    Export to reference management software   RIS file
      BibTeX file
    Source: Union catalogues
    Language: English
    Media type: Book
    Format: Online
    Series: Array ; DP18830
    Subjects: Religion; Pandemics; Depression
    Scope: 1 Online-Ressource (circa 30 Seiten), Illustrationen
  4. Second United Nations survey on Latin American and Caribbean youth within the context of the COVID-19 pandemic
    report of results
    Published: 2022
    Publisher:  United Nations, Santiago

    In 2021, the entities of the United Nations system in Latin America and the Caribbean that are members of the Working Group on Youth of the Regional Collaborative Platform for Latin America and the Caribbean launched a second online survey. The aim... more

    Access:
    Verlag (kostenfrei)
    Resolving-System (kostenfrei)
    Ibero-Amerikanisches Institut Preußischer Kulturbesitz, Bibliothek
    Unlimited inter-library loan, copies and loan

     

    In 2021, the entities of the United Nations system in Latin America and the Caribbean that are members of the Working Group on Youth of the Regional Collaborative Platform for Latin America and the Caribbean launched a second online survey. The aim was to assess how young people were living a year after the outbreak of the COVID-19 pandemic and what were their concerns about the present and the future. The survey was conducted between August and October 2021 among young people aged 15–29, with more than 46,000 respondents from 42 countries and territories in the region. The main findings of the survey are presented in this report. Introduction .-- I. Description of sample .-- II. Survey results. A. Life during the pandemic. B. Education. C. Paid and unpaid work. D. Use of time and consumer practices. E. Health. F. Community, citizen participation and governance. G. Outlook for the future .-- III. Conclusion.

     

    Export to reference management software   RIS file
      BibTeX file
  5. La inclusión de pueblos indígenas y afrodescendientes en los sistemas de información de salud en el marco de la pandemia de COVID-19
    Published: 2022
    Publisher:  Comisión Económica para América Latina y el Caribe (CEPAL), Santiago

    Reunión virtual El presente documento contiene los principales resultados del Seminario Regional “La inclusión de pueblos indígenas y afrodescendientes en los sistemas de información en salud en el marco de la pandemia por COVID-19”, realizado de... more

    Access:
    Verlag (kostenfrei)
    Resolving-System (kostenfrei)
    Ibero-Amerikanisches Institut Preußischer Kulturbesitz, Bibliothek
    Unlimited inter-library loan, copies and loan

     

    Reunión virtual El presente documento contiene los principales resultados del Seminario Regional “La inclusión de pueblos indígenas y afrodescendientes en los sistemas de información en salud en el marco de la pandemia por COVID-19”, realizado de manera virtual entre los días 8 y 9 de septiembre de 2021. El evento fue organizado por el Centro Latinoamericano y Caribeño de Demografía (CELADE)-División de Población de la Comisión Económica para América Latina y el Caribe (CEPAL), la Organización Panamericana de la Salud (OPS) y el Fondo de Población de Naciones Unidas (UNFPA). Dicho Seminario tuvo por objetivo hacer una revisión de la información en salud con enfoque étnico-racial, teniendo en cuenta los actuales desafíos que enfrentan los países de la región para la superación de la crisis sanitaria y el logro de una igualdad efectiva, acorde con los derechos individuales y colectivos de los pueblos indígenas y afrodescendientes. Resumen .-- Introducción .-- I. Antecedentes y justificación .-- II. Desarrollo del seminario. A. Síntesis de las palabras inaugurales. B. La inclusión de la identificación de pueblos indígenas y afrodescendientes en las estadísticas vitales. C. La inclusión de la identificación de pueblos indígenas y afrodescendientesen los sistemas de información en salud .-- III. Desafíos y recomendaciones.

     

    Export to reference management software   RIS file
      BibTeX file
  6. Profits, pandemics, and lockdown effectiveness in nursing home networks
    Published: 2022
    Publisher:  Global Labor Organization (GLO), Essen

    How do pandemics affect for-profit and not-for-profit organizations differently? To address this question, we analyze optimal lockdowns in a two-sector continuous-time individual-based mean-field epidemiological model. We uncover a unique solution... more

    Access:
    Verlag (kostenfrei)
    Resolving-System (kostenfrei)
    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
    DS 565
    No inter-library loan

     

    How do pandemics affect for-profit and not-for-profit organizations differently? To address this question, we analyze optimal lockdowns in a two-sector continuous-time individual-based mean-field epidemiological model. We uncover a unique solution that depends on network structure, lockdown effectiveness, and the planner's tolerable infection incidence. Using unique data on nursing home networks in the United States, we calibrate the model and jointly quantify state-level lockdown effectiveness and preference for enforcing stringent containment strategies during the COVID-19 pandemic. We also empirically validate simulation results derived from the theoretical analyses. We find that for-profit nursing homes experience higher COVID-19 death rates than not-for-profit nursing homes. In addition, this differential health effect increases with lockdown effectiveness.

     

    Export to reference management software   RIS file
      BibTeX file
    Source: Union catalogues
    Language: English
    Media type: Book
    Format: Online
    Other identifier:
    hdl: 10419/261322
    Series: GLO discussion paper ; no. 1131
    Subjects: Pandemics; Profits; Social networks; Lockdown effectiveness; Nursing Homes
    Scope: 1 Online-Ressource (circa 57 Seiten), Illustrationen
  7. Network exposure in the propagation of the COVID-19 pandemic
    Published: September 10, 2021
    Publisher:  Verein für Socialpolitik, [Köln]

    This paper develops a parsimonious model of individual exposure and of public health policy that can be used to study the evolution of an epidemic and the optimal use of lockdown policies and other non-pharmaceutical interventions. At the heart of... more

    Access:
    Resolving-System (kostenfrei)
    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
    DSM 13
    No inter-library loan

     

    This paper develops a parsimonious model of individual exposure and of public health policy that can be used to study the evolution of an epidemic and the optimal use of lockdown policies and other non-pharmaceutical interventions. At the heart of individual exposure choices are the trade-offs between private utility derived from exposure and the risks of infection. Agents' utilities from private exposure are amplified by network benefits from social and economic activities, which amplifies the infection externality and constitutes a role for coordination policies due to multiple equilibria. We find that lockdowns do not prevail endogenously in equilibrium and that containment policy can significantly enhance welfare. Unpopularity of such contact restrictions imply that policy might face time inconsistency problems.

     

    Export to reference management software   RIS file
      BibTeX file
    Source: Union catalogues
    Language: English
    Media type: Book
    Format: Online
    Other identifier:
    hdl: 10419/242465
    Series: Jahrestagung 2021 / Verein für Socialpolitik ; 124
    Subjects: Pandemics; Endogenous exposure; SIR-macro; Network effects;Externality; Time inconsistency
    Scope: 1 Online-Ressource (circa 26 Seiten), Illustrationen
  8. Profits, pandemics, and lockdown effectiveness in nursing home networks
    Published: September 2022
    Publisher:  National Institute of Economic and Social Research, London

    Access:
    Verlag (kostenfrei)
    Verlag (kostenfrei)
    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
    VS 538
    No inter-library loan
    Export to reference management software   RIS file
      BibTeX file
    Source: Union catalogues
    Language: English
    Media type: Book
    Format: Online
    Series: NIESR discussion paper ; no. 540 (15 September 2022)
    Subjects: Pandemics; Profits; Social networks; Lockdown effectiveness; Nursing Homes
    Scope: 1 Online-Ressource (circa 59 Seiten), Illustrationen
  9. Structural breaks in global stock markets
    are they caused by pandemics, protests or other factors?
    Published: [2022]
    Publisher:  African Governance and Development Institute, [Yaoundé]

    The aim of this study is to examine the impact of the COVID-19 pandemic and other similar global events on the global stock market. The data used covers 16 countries of the world and a series of quarterly data ranging from 1919Q1 to 2020Q2 for major... more

    Access:
    Verlag (kostenfrei)
    Verlag (kostenfrei)
    Resolving-System (kostenfrei)
    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
    DS 524
    No inter-library loan

     

    The aim of this study is to examine the impact of the COVID-19 pandemic and other similar global events on the global stock market. The data used covers 16 countries of the world and a series of quarterly data ranging from 1919Q1 to 2020Q2 for major stock market index was used. The Bai and Perron's multiple structural break approach were adopted. Different number of break dates is noticed across several regions. While selected sample countries in Europe have at least ten break dates under the period of investigation, we observe for US, Canada and Australia, only twelve break dates. Asia and the other bloc of countries report ten and twelve break dates respectively. Notably, one most prominent causes of structural changes in stock markets (with the exclusion of Germany) appears to be from the GFC, which had inverse effects on major market around the world. The most prominent source of structural breaks in the Asian markets appears to be from the 2008-2009 GFC. In addition, we found evidence of structural breaks in several stock markets in the world, resulting from the 2009-2010 Global Pandemic, that is, the H1N1 virus/pigs Swine Flu; 2003 SARS; MERS; and EBOLA. In addition, as explained above, events have the tendency of unfolding over time; hence matching exact breaks in stock market data to precise events is very unlikely.

     

    Export to reference management software   RIS file
      BibTeX file
    Source: Union catalogues
    Language: English
    Media type: Book
    Format: Online
    Other identifier:
    hdl: 10419/269077
    Series: AGDI working paper ; WP/22, 076
    Subjects: Pandemics; Stock Market Index; Structural Breaks; Bai and Perron multiple break; Global events
    Scope: 1 Online-Ressource (circa 49 Seiten)
  10. Quarantine
    Published: 2022
    Publisher:  Swift, London

    "It's ten years since a deadly pandemic swept the globe, and five years since the last new recorded case. Society came close to collapse, but now there's a vaccine - though not a cure - people are only dying in the usual ways. Lukas, along with... more

    Universitätsbibliothek der Eberhard Karls Universität
    62 A 5334
    Unlimited inter-library loan, copies and loan

     

    "It's ten years since a deadly pandemic swept the globe, and five years since the last new recorded case. Society came close to collapse, but now there's a vaccine - though not a cure - people are only dying in the usual ways. Lukas, along with several hundred other infected people, is quarantined in a camp on a mountain of Central Asia. With nothing to do, and no future to speak of, the inmates pass the time drinking, taking drugs, joining a cult, making art or having sex with whoever they can. Rebecca is a scientist who worked on the vaccine that saved the world. Having lost her partner in the years of chaos, she keeps testing the vaccine against mutations of the virus, because it seems inevitable that there will be a next time."--Publisher

     

    Export to reference management software   RIS file
      BibTeX file
  11. Southeast Asia rising from the pandemic
    Published: March 2022
    Publisher:  Asian Development Bank, Mandaluyong City, Metro Manila, Philippines

    Access:
    Verlag (kostenfrei)
    Resolving-System (kostenfrei)
    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
    No inter-library loan
    Export to reference management software   RIS file
      BibTeX file
    Source: Union catalogues
    Language: English
    Media type: Ebook
    Format: Online
    ISBN: 9789292694067; 9789292694074
    Other identifier:
    Subjects: Coronavirus; Coping-Strategie; Entwicklung; Südostasien; COVID-19 (Disease); COVID-19 (Disease); COVID-19 (Disease); Pandemics
    Scope: 1 Online-Ressource (circa 126 Seiten), Illustrationen
  12. Determinants of Covid-19 vaccine rollouts and their effects on health outcomes
    Published: 31 October 2021
    Publisher:  Centre for Economic Policy Research, London

    Access:
    Verlag (lizenzpflichtig)
    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
    LZ 161
    No inter-library loan
    Universitätsbibliothek Mannheim
    No inter-library loan
    Export to reference management software   RIS file
      BibTeX file
    Source: Union catalogues
    Language: English
    Media type: Book
    Format: Online
    Series: Array ; DP16681
    Subjects: COVID-19; Pandemics; vaccinations; containment measures
    Scope: 1 Online-Ressource (circa 53 Seiten), Illustrationen
  13. The effects of Covid-19 vaccines on economic activity
    Published: 31 October 2021
    Publisher:  Centre for Economic Policy Research, London

    Access:
    Verlag (lizenzpflichtig)
    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
    LZ 161
    No inter-library loan
    Universitätsbibliothek Mannheim
    No inter-library loan
    Export to reference management software   RIS file
      BibTeX file
    Source: Union catalogues
    Language: English
    Media type: Book
    Format: Online
    Series: Array ; DP16682
    Subjects: COVID-19; Pandemics; vaccinations; containment measures; COVID-19; Pandemics; vaccinations; containment measures
    Scope: 1 Online-Ressource (circa 49 Seiten), Illustrationen
  14. Religion, Covid-19 and mental health
    Published: 6 January 2023
    Publisher:  University of Cambridge, Faculty of Economics, [Cambridge]

    Access:
    Verlag (kostenfrei)
    Resolving-System (kostenfrei)
    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
    VSP 1362
    No inter-library loan
    Export to reference management software   RIS file
      BibTeX file
    Source: Union catalogues
    Language: English
    Media type: Book
    Format: Online
    Other identifier:
    Series: Cambridge working paper in economics ; 2302
    Subjects: Religion; Religiosity; Mental health; Covid-19; Pandemics
    Scope: 1 Online-Ressource (circa 39 Seiten), Illustrationen
  15. Covid-19 vaccines, innovation, and intellectual property rights
    Published: 2022
    Publisher:  Global Labor Organization (GLO), Essen

    Should the intellectual property rights on the first Covid-19 vaccines be temporarily lifted in applying the Trade-Related Aspect of Intellectual Property (TRIPS) flexibility? Is it right to grant the first generation of Covid-19 vaccines a special... more

    Access:
    Verlag (kostenfrei)
    Resolving-System (kostenfrei)
    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
    DS 565
    No inter-library loan

     

    Should the intellectual property rights on the first Covid-19 vaccines be temporarily lifted in applying the Trade-Related Aspect of Intellectual Property (TRIPS) flexibility? Is it right to grant the first generation of Covid-19 vaccines a special treatment from an IPR perspective? On what grounds? By extensively reviewing the available medical and economic literature on the subject, this chapter will guide the reader step-by-step to the leading scientific, political, and cultural challenges in granting broad worldwide access to vaccination. The accumulated delays in providing effective Covid-19 vaccine intervention in the low- and middle-income countries are ultimately responsible for the virus circulation at the global level and the proliferation of immunity-escaping variants. Therefore governmental rationality around the world would suggest any possible active policy tool to scale up the current vaccines supply. However, not to prevent future investment in R&D, the governments should bear the cost of the expected increased industry obsolescence determined by a temporary patent waiver; this includes public patent-buy-outs and regulated public-private R&D partnerships.

     

    Export to reference management software   RIS file
      BibTeX file
    Source: Union catalogues
    Language: English
    Media type: Book
    Format: Online
    Other identifier:
    hdl: 10419/256807
    Series: GLO discussion paper ; no. 1095
    Subjects: Vaccines; Covid-19; Pandemics; Patents; Innovation
    Scope: 1 Online-Ressource (circa 38 Seiten)
  16. Religion, covid-19 and mental health
    Published: 09 January 2023
    Publisher:  Centre for Economic Policy Research, London

    Access:
    Verlag (lizenzpflichtig)
    Verlag (lizenzpflichtig)
    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
    LZ 161
    No inter-library loan
    Universitätsbibliothek Mannheim
    No inter-library loan
    Export to reference management software   RIS file
      BibTeX file
    Source: Union catalogues
    Language: English
    Media type: Book
    Format: Online
    Series: Array ; DP17791
    Subjects: Religion; Religiosity; Mental health; Covid-19; Pandemics
    Scope: 1 Online-Ressource (circa 41 Seiten), Illustrationen
  17. Global macroeconomic scenarios of the COVID-19 pandemic
    Published: [2020]
    Publisher:  CEPAR, ARC Centre of Excellence in Population Ageing Research, [Kensington, NSW]

    Access:
    Verlag (kostenfrei)
    Verlag (kostenfrei)
    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
    Keine Rechte
    No inter-library loan
    Export to reference management software   RIS file
      BibTeX file
    Source: Union catalogues
    Language: English
    Media type: Book
    Format: Online
    Series: Working paper / CEPAR, ARC Centre of Excellence in Population Ageing Research ; 2020, 19
    Subjects: Coronavirus; Epidemie; Infektionskrankheit; Szenariotechnik; Dynamisches Gleichgewicht; CGE-Modell; DSGE-Modell; Theorie; Pandemics; infectious diseases; risk; macroeconomics; DSGE; CGE; G-Cubed
    Scope: 1 Online-Ressource (circa 59 Seiten), Illustrationen
  18. Creative against the pandemic
    measuring creativity in rural India
    Published: 17 January 2022
    Publisher:  Centre for Economic Policy Research, London

    Access:
    Verlag (lizenzpflichtig)
    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
    LZ 161
    No inter-library loan
    Universitätsbibliothek Mannheim
    No inter-library loan
    Export to reference management software   RIS file
      BibTeX file
    Source: Union catalogues
    Language: English
    Media type: Book
    Format: Online
    Series: Array ; DP16915
    Subjects: Creativity; Soft skills; Mixed-methods; Pandemics; Social Connectedness; India
    Scope: 1 Online-Ressource (circa 41 Seiten)
  19. A time of great intensity
    the pandemic effect on work, care work and subjective wellbeing in MENA countries
    Published: [2021]
    Publisher:  Economic Research Forum (ERF), Dokki, Giza, Egypt

    Access:
    Verlag (kostenfrei)
    Verlag (kostenfrei)
    Verlag (kostenfrei)
    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
    VS 592
    No inter-library loan
    Export to reference management software   RIS file
      BibTeX file
    Source: Union catalogues
    Language: English
    Media type: Book
    Format: Online
    Series: ERF working papers series ; no. 1528 (December 2021)
    Subjects: Pandemics; care work; subjective wellbeing; unemployment; MENA region
    Scope: 1 Online-Ressource (circa 31 Seiten), Illustrationen
  20. Unequal mortality during the Spanish Flu
    Published: February 2021
    Publisher:  Economic History Department, London School of Economics and Political Science, London, UK

    Access:
    Verlag (kostenfrei)
    Verlag (kostenfrei)
    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
    VS 783
    No inter-library loan
    Export to reference management software   RIS file
      BibTeX file
    Source: Union catalogues
    Language: English
    Media type: Book
    Format: Online
    Series: Economic history working papers / London School of Economics and Political Science ; no: 325
    Subjects: Pandemics; Health Inequality; Socio-Economic Mortality Differences; Urban Penalty
    Scope: 1 Online-Ressource (circa 26 Seiten), Illustrationen
  21. Local institutions and pandemics
    city autonomy and the Black Death
    Published: 30 September 2021
    Publisher:  Centre for Economic Policy Research, London

    Access:
    Verlag (lizenzpflichtig)
    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
    LZ 161
    No inter-library loan
    Universitätsbibliothek Mannheim
    No inter-library loan
    Export to reference management software   RIS file
      BibTeX file
    Source: Union catalogues
    Language: English
    Media type: Book
    Format: Online
    Series: Array ; DP16593
    Subjects: Local institutions; Pandemics; city autonomy; Black Death; Europe
    Scope: 1 Online-Ressource (circa 40 Seiten), Illustrationen
  22. Accelerating Vaccine Innovation for Emerging Infectious Diseases via Parallel Discovery

    The portfolio approach of financing drug development has been proposed as a financial innovation to improve the risk/return tradeoff of investment in drug development projects through the use of diversification and securitization. By investing in a... more

    Access:
    Verlag (kostenfrei)
    Resolving-System (kostenfrei)
    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
    No inter-library loan

     

    The portfolio approach of financing drug development has been proposed as a financial innovation to improve the risk/return tradeoff of investment in drug development projects through the use of diversification and securitization. By investing in a sizable and well-diversified portfolio of novel drug candidates, and issuing equity and securitized debt based on this portfolio, the financial performance of such a biomedical “megafund” can be made attractive to a wide group of investors in the private sector. To analyze the viability of the portfolio approach in expediting vaccine development against emerging infectious diseases, we simulate the financial performance of a hypothetical vaccine megafund consisting of 120 mRNA vaccine candidates in the preclinical stage, which target 11 emerging infectious diseases, including a hypothetical “disease X,” which may cause the next global pandemic. We calibrate the simulation parameters with input from domain experts in mRNA technology and an extensive literature review. We find that this vaccine portfolio will generate an average annualized return on investment of −6.0% per annum and a negative net present value of −$9.5 billion, despite the scientific advantages of mRNA technology and the financial benefits of diversification. We also show that clinical trial costs account for 94% of the total investment, while vaccine manufacturing costs account for only 6%. The most important factor of the megafund's financial performance is the price per vaccine dose, while other factors, such as the increased probability of success due to mRNA technology, the size of the megafund portfolio, and the possibility of conducting human challenge trials do not significantly improve its financial performance. Our results illustrate the critical importance of government funding to ensure that vaccine development will be financially sustainable for the private sector and that effective vaccines will be available to prevent the next global pandemic

     

    Export to reference management software   RIS file
      BibTeX file
    Source: Union catalogues
    Language: English
    Media type: Book
    Format: Online
    Other identifier:
    Series: MIT Sloan Research Paper ; No. 6858-23
    Subjects: Vaccines; mRNA; Megafund; Pandemics; Epidemics; Infectious Diseases; Healthcare Finance
    Other subjects: Array
    Scope: 1 Online-Ressource (31 p)
    Notes:

    Nach Informationen von SSRN wurde die ursprüngliche Fassung des Dokuments March 16, 2023 erstellt

  23. The political effects of the 1918 influenza pandemic in Weimar Germany
    Published: June 2023
    Publisher:  ECONtribute, [Bonn]

    How do health crises affect election results? We combine a panel of election results from 1893-1933 with spatial heterogeneity in excess mortality due to the 1918 Influenza to assess the pandemic's effect on voting behavior across German... more

    Access:
    Verlag (kostenfrei)
    Verlag (kostenfrei)
    Resolving-System (kostenfrei)
    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
    DS 711
    No inter-library loan

     

    How do health crises affect election results? We combine a panel of election results from 1893-1933 with spatial heterogeneity in excess mortality due to the 1918 Influenza to assess the pandemic's effect on voting behavior across German constituencies. Applying a dynamic differences-in-differences approach, we find that areas with higher influenza mortality saw a lasting shift towards left-wing parties. We argue that pandemic intensity increased the salience of public health policy, prompting voters to reward parties signaling competence in health issues. Alternative explanations such as pandemic-induced economic hardship, punishment of incumbents for inadequate policy responses, or polarization of the electorate towards more extremist parties are not supported by our findings.

     

    Export to reference management software   RIS file
      BibTeX file
    Source: Union catalogues
    Language: English
    Media type: Book
    Format: Online
    Other identifier:
    hdl: 10419/278536
    Series: ECONtribute discussion paper ; no. 241
    Subjects: Pandemics; Elections; Health; Voting behavior; Issue salience; Issue ownership; Weimar Republic
    Scope: 1 Online-Ressource (circa 61 Seiten), Illustrationen
  24. La inclusión de pueblos indígenas y afrodescendientes en los sistemas de información de salud en el marco de la pandemia de COVID-19
    Published: 2022
    Publisher:  Comisión Económica para América Latina y el Caribe (CEPAL), Santiago

    Reunión virtual El presente documento contiene los principales resultados del Seminario Regional “La inclusión de pueblos indígenas y afrodescendientes en los sistemas de información en salud en el marco de la pandemia por COVID-19”, realizado de... more

    Access:
    Verlag (kostenfrei)
    Resolving-System (kostenfrei)
    Ibero-Amerikanisches Institut Preußischer Kulturbesitz, Bibliothek
    No inter-library loan
    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
    VS 404
    No inter-library loan

     

    Reunión virtual El presente documento contiene los principales resultados del Seminario Regional “La inclusión de pueblos indígenas y afrodescendientes en los sistemas de información en salud en el marco de la pandemia por COVID-19”, realizado de manera virtual entre los días 8 y 9 de septiembre de 2021. El evento fue organizado por el Centro Latinoamericano y Caribeño de Demografía (CELADE)-División de Población de la Comisión Económica para América Latina y el Caribe (CEPAL), la Organización Panamericana de la Salud (OPS) y el Fondo de Población de Naciones Unidas (UNFPA). Dicho Seminario tuvo por objetivo hacer una revisión de la información en salud con enfoque étnico-racial, teniendo en cuenta los actuales desafíos que enfrentan los países de la región para la superación de la crisis sanitaria y el logro de una igualdad efectiva, acorde con los derechos individuales y colectivos de los pueblos indígenas y afrodescendientes. Resumen .-- Introducción .-- I. Antecedentes y justificación .-- II. Desarrollo del seminario. A. Síntesis de las palabras inaugurales. B. La inclusión de la identificación de pueblos indígenas y afrodescendientes en las estadísticas vitales. C. La inclusión de la identificación de pueblos indígenas y afrodescendientesen los sistemas de información en salud .-- III. Desafíos y recomendaciones.

     

    Export to reference management software   RIS file
      BibTeX file
  25. Second United Nations survey on Latin American and Caribbean youth within the context of the COVID-19 pandemic
    report of results
    Published: 2022
    Publisher:  United Nations, Santiago

    In 2021, the entities of the United Nations system in Latin America and the Caribbean that are members of the Working Group on Youth of the Regional Collaborative Platform for Latin America and the Caribbean launched a second online survey. The aim... more

    Access:
    Verlag (kostenfrei)
    Resolving-System (kostenfrei)
    Ibero-Amerikanisches Institut Preußischer Kulturbesitz, Bibliothek
    No inter-library loan
    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
    No inter-library loan

     

    In 2021, the entities of the United Nations system in Latin America and the Caribbean that are members of the Working Group on Youth of the Regional Collaborative Platform for Latin America and the Caribbean launched a second online survey. The aim was to assess how young people were living a year after the outbreak of the COVID-19 pandemic and what were their concerns about the present and the future. The survey was conducted between August and October 2021 among young people aged 15–29, with more than 46,000 respondents from 42 countries and territories in the region. The main findings of the survey are presented in this report. Introduction .-- I. Description of sample .-- II. Survey results. A. Life during the pandemic. B. Education. C. Paid and unpaid work. D. Use of time and consumer practices. E. Health. F. Community, citizen participation and governance. G. Outlook for the future .-- III. Conclusion.

     

    Export to reference management software   RIS file
      BibTeX file