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  1. Genes
    a very short introduction
    Author: Slack, Jonathan M. W.
    Published: 2014
    Publisher:  Oxford Univ. Press, Oxford

    Location:
    Universitäts- und Stadtbibliothek Köln, Hauptabteilung
    Signature:
    17B8442
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    Location:
    Landesbibliothekszentrum Rheinland-Pfalz / Pfälzische Landesbibliothek
    Signature:
    116-1322
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    04
  2. Genes
    a very short introduction
    Author: Slack, Jonathan M. W
    Published: 2014
    Publisher:  Oxford Univ. Press, Oxford

    Location:
    Universitäts- und Stadtbibliothek Köln, Hauptabteilung
    Inter-library loan:
    Unlimited inter-library loan, copies and loan

    Location:
    Landesbibliothekszentrum Rheinland-Pfalz / Pfälzische Landesbibliothek
    Inter-library loan:
    Unlimited inter-library loan, copies and loan
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    04
  3. Nucleotide modification and base conversion of RNA
    Contributor: Grosjean, Henri (Hrsg.)
    Published: 19XX-
    Publisher:  Elsevier, Paris

    Location:
    Kommunikations-, Informations- und Medienzentrum der Universität Hohenheim
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    Source: Union catalogues
    Contributor: Grosjean, Henri (Hrsg.)
    Language: English
    Media type: Book
    Format: Print
    Series: Biochimie ; ...
    Subjects: Nucleotide; Modifikation <Biochemie>; RNS-Edierung;
  4. Identification and analysis of patterns in DNA sequences, the genetic code and transcriptional gene regulation
    Author: Nikolajewa, Swetlana
    Published: 2006

    The present cumulative work consists of six articles linked by the topic ʺIdentification and Analysis of Patterns in DNA sequences, the Genetic Code and Transcriptional Gene Regulationʺ. We have applied a binary coding, to efficiently findpatterns... more

    Location:
    Universitätsbibliothek Braunschweig
    Signature:
    4554-7968
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    Location:
    Technische Informationsbibliothek (TIB) / Leibniz-Informationszentrum Technik und Naturwissenschaften und Universitätsbibliothek
    Signature:
    H 07 B 484
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    Location:
    Thüringer Universitäts- und Landesbibliothek
    Signature:
    2006 J 283
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    The present cumulative work consists of six articles linked by the topic ʺIdentification and Analysis of Patterns in DNA sequences, the Genetic Code and Transcriptional Gene Regulationʺ. We have applied a binary coding, to efficiently findpatterns within nucleotide sequences. In the first and second part of my work one single bit to encode all four nucleotides is used. The three possibilities of a one - bit coding are: keto (G,U) - amino (A,C) bases, strong (G,C) - weak (A,U) bases, and purines (G,A) - pyrimidines (C,U). We found out that the best pattern could be observed using the purine - pyrimidine coding. Applying this coding we have succeeded in finding a new representation of the genetic code which has been published under the title ʺA New Classification Scheme of the Genetic Codeʺ in ʺJournal of Molecular Biologyʺ and ʺA Purine-Pyrimidine Classification Scheme of the Genetic Codeʺ in ʺBIOForum Europeʺ. This new representation enables to reduce the common table of the genetic code from 64 to 32 fields maintaining the same information content. It turned out that all known and even new patterns of the genetic code can easily be recognized in this new scheme. Furthermore, our new representation allows us for speculations about the origin and evolution of the translation machinery and the genetic code. Thus, we found a possible explanation for the contemporary codon - amino acid assignment and wide support for an early doublet code. Those explanations have been published in ʺJournal of Bioinformatics and Computational Biologyʺ under the title ʺThe New Classification Scheme of the Genetic Code, its Early Evolution, and tRNA Usageʺ. Assuming to find these purine - pyrimidine patterns at the DNA level itself, we examined DNA binding sites for the occurrence of binary patterns. A comprehensive statistic about the largest class of restriction enzymes (type II) has shown a very distinctive purine - pyrimidine pattern. Moreover, we have observed a higher G+C content for the protein binding sequences. For both observations we have provided and discussed several explanations published under the title ʺCommon Patterns in Type II Restriction Enzyme Binding Sitesʺ in ʺNucleic Acid Researchʺ. The identified patterns may help to understand how a protein finds its binding site. In the last part of my work two submitted articles about the analysis of Boolean functions are presented. Boolean functions are used for the description and analysis of complex dynamic processes and make it easier to find binary patterns within biochemical interaction networks.

     
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    Source: Union catalogues
    Language: English
    Media type: Dissertation
    Format: Print
    Subjects: Molekulargenetik; Molekulare Evolution; Nucleotide; Genregulation; Nucleotidsequenz; Genregulation; Basenpaarung; Codierung; Genetischer Code <Motiv>; Molekulare Evolution; Boolesche Funktion;
    Scope: 102 Blätter, Illustrationen, Diagramme, 29 cm
    Notes:

    Dissertation, Friedrich-Schiller-Universität Jena, 2006