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  1. RNA and DNA editing
    molecular mechanisms and their integration into biological systems
    Contributor: Smith, Harold C. (Hrsg.)
    Published: 2008
    Publisher:  Wiley, Hoboken, NJ

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    Universitätsbibliothek J. C. Senckenberg, Zentralbibliothek (ZB)
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    33.053.17
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    Universität Mainz, Zentralbibliothek
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    242.996
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    Content information
    Source: Union catalogues
    Contributor: Smith, Harold C. (Hrsg.)
    Language: English
    Media type: Book
    Format: Print
    ISBN: 9780470109915; 0470109912
    RVK Categories: WD 5355 ; WD 5360
    Subjects: RNS-Edierung; DNS
    Scope: XXIII, 426 S., Ill.
    Notes:

    Literaturangaben
  2. RNA and DNA editing
    molecular mechanisms and their integration into biological systems
    Contributor: Smith, Harold C.
    Published: 2008
    Publisher:  Wiley-Interscience, Hoboken

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    Universitätsbibliothek Gießen
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    Universitätsbibliothek Kassel, Landesbibliothek und Murhardsche Bibliothek der Stadt Kassel
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    Content information
    Source: Union catalogues
    Contributor: Smith, Harold C.
    Language: English
    Media type: Ebook
    Format: Online
    ISBN: 9780470109915; 0470109912
    Other identifier:
    RVK Categories: WD 5355 ; WG 1700 ; WG 1800 ; WD 5360
    Subjects: RNS-Edierung; DNS
    Scope: XXIII, 426 S., [12] Bl., Ill., graph. Darst., 25 cm
    Notes:

    Includes bibliographical references and index.

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  3. RNA and DNA Editing
    Molecular Mechanisms and Their Integration into Biological Systems
    Author: Smith, Harold C.
    Published: 2008; ©2008.
    Publisher:  John Wiley & Sons, Incorporated, Hoboken

    Harold C. Smith, PhD, is Professor in the Department of Biochemistry and Biophysics at the University of Rochester and the founder and Chief Scientific Officerof OyaGen, a biotech company that develops drugs that target editing enzymes. Dr. Smith... more

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    Universitätsbibliothek Erfurt / Forschungsbibliothek Gotha, Universitätsbibliothek Erfurt
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    Duale Hochschule Baden-Württemberg Heidenheim, Bibliothek
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    Bibliothek LIV HN Sontheim
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    Bibliothek LIV HN Sontheim
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    Deutsches Zentrum für Luft- und Raumfahrt, DLR-Bibliothek
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    Duale Hochschule Baden-Württemberg Lörrach, Zentralbibliothek
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    Hochschulbibliothek Friedensau
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    Kommunikations-, Informations- und Medienzentrum der Universität Hohenheim
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    Harold C. Smith, PhD, is Professor in the Department of Biochemistry and Biophysics at the University of Rochester and the founder and Chief Scientific Officerof OyaGen, a biotech company that develops drugs that target editing enzymes. Dr. Smith organized the first Gordon Research Conference on RNA Editing in 1997 and holds four patents. Intro -- RNA AND DNA EDITING -- CONTENTS -- PREFACE -- ACKNOWLEDGMENTS -- CONTRIBUTORS -- PART I DIVERSIFICATION OF THE PROTEOME THROUGH RNA AND DNA EDITING -- CHAPTER 1 DIVERSIFYING EXON CODE THROUGH A-TO-I RNA EDITING -- 1.1 Introduction and Background -- 1.1.1 Initial Discovery and Context of A-to-I RNA Editing and ADARs -- 1.1.2 Important Cases of Recoding by A-to-I Modification in Pre-mRNA -- 1.1.3 Cis-Acting Features for A-to-I Editing -- 1.1.4 Properties of the A-to-I Editing Machinery -- 1.2 Main Questions in the Field and Approaches -- 1.2.1 Biochemical Versus Computational Approaches -- 1.2.2 Editing of miRNA Sequences -- 1.3 Future Directions: Evolution of Editing Sites and Machinery -- References -- CHAPTER 2 ANTIBODY GENE DIVERSIFICATION BY AID-CATALYZED DNA EDITING -- 2.1 Introduction -- 2.2 Before AID -- 2.2.1 Without DNA (Darkness) and with DNA (Light) -- 2.2.2 Prominent Early Models for Antibody Diversification -- 2.2.3 How Protein Sequencing Technology Enabled an Understanding of Antibody Diversity -- 2.2.4 Somatic DNA Rearrangements Underpin V(D)J Joining and Create the Primary Antibody Repertoire -- 2.2.5 Additional Antibody Diversity by Somatic Hypermutation (and Gene Conversion in Some Animals) -- 2.2.6 Altering Antibody Function by Class Switch Recombination (Isotype Switching) -- 2.3 After AID -- 2.3.1 A Novel Deaminase Is Required for CSR, SHM, and IGC -- 2.3.2 AID Is a DNA Cytosine Deaminase that Directly Triggers Antibody Diversification -- 2.3.3 The Importance of Uracil Bases in DNA In Vivo -- 2.3.4 Processing of AID-induced Lesions: The Molecular Mechanism of Somatic-Hypermutation -- 2.3.5 Processing of AID-induced Lesions: The Molecular Mechanism of Immunoglobulin Gene Conversion -- 2.3.6 Processing of AID-induced Lesions: The Molecular Mechanism of Class Switch Recombination -- 2.4 Hot Areas and Speculations.

     
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    Volltext (lizenzpflichtig)
    Source: Union catalogues
    Language: English
    Media type: Ebook
    Format: Online
    ISBN: 9780470262252
    RVK Categories: WD 5355 ; WD 5360
    Edition: 1st ed.
    Subjects: Nucleotide sequence; DNA; Genetic transcription; Nucleotide sequence; RNA editing; Electronic books
    Scope: 1 online resource (464 pages)
    Notes:

    Description based on publisher supplied metadata and other sources
  4. RNA and DNA editing
    molecular mechanisms and their integration into biological systems
    Contributor: Smith, Harold C.
    Published: 2008
    Publisher:  Wiley-Interscience, Hoboken, N.J. ; EBSCO Industries, Inc., Birmingham, AL, USA

    Latest discoveries in RNA and DNA editing research, with expert forecasts of the field's future directions. RNA and DNA Editing assembles a team of leading experts who present the latestdiscoveries in the field alongside the latest models and met. more

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    Bibliothek der Hochschule Mainz, Untergeschoss
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    Latest discoveries in RNA and DNA editing research, with expert forecasts of the field's future directions. RNA and DNA Editing assembles a team of leading experts who present the latestdiscoveries in the field alongside the latest models and met.

     
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    Source: Union catalogues
    Contributor: Smith, Harold C.
    Language: English
    Media type: Ebook
    Format: Online
    ISBN: 9780470262252; 0470262257; 9780470262269; 0470262265; 1281237531; 9781281237538
    RVK Categories: WD 5355 ; WD 5360
    Subjects: RNS-Edierung; DNS
    Scope: 1 Online-Ressource (xxiii, 426 pages, [12] pages of plates), Illustrations (some color)
    Notes:

    Includes bibliographical references and index
  5. RNA and DNA editing
    molecular mechanisms and their integration into biological systems
    Contributor: Smith, Harold C. (Hrsg.)
    Published: c 2008
    Publisher:  Wiley-Interscience, Hoboken, NJ

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    Sächsische Landesbibliothek - Staats- und Universitätsbibliothek Dresden
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    Universitätsbibliothek Greifswald
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    660/WD 5300 S649
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    Publikations- und Informationsservice, Max-Planck-Institut für Multidisziplinäre Naturwissenschaften
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    E 16 c/70

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    Universitätsbibliothek Heidelberg
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    UBN/WD 5355 S649
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    Karlsruher Institut für Technologie, KIT-Bibliothek
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    2008 A 2491
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    Universitätsbibliothek Kiel, Zentralbibliothek
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    Universität Leipzig, Universitätsbibliothek, Bibliothek Medizin/Naturwissenschaften
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    Universitätsbibliothek Stuttgart
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    Universitätsbibliothek der Eberhard Karls Universität
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    Source: Union catalogues
    Contributor: Smith, Harold C. (Hrsg.)
    Language: English
    Media type: Book
    Format: Print
    ISBN: 0470109912; 9780470109915
    Other identifier:
    2007039289
    RVK Categories: WD 5360 ; WD 5355
    Subjects: RNA editing; DNA; Nucleotide sequence; Genetic transcription; RNA Editing; Base Sequence; Genomics; Transcription, Genetic; RNA editing; DNA; Nucleotide sequence; Genetic transcription
    Scope: XXIII, 426 S., Ill., graph. Darst., 25 cm
    Notes:

    Includes bibliographical references and index